Gene detail

Detailed information of ENSQNNP00000023009.1 in Candelabrum cocksii

Genomic Location: chr1:4160831...4168628
NR annotation: XP_002158963.2, zinc finger MIZ domain-containing protein 1 isoform X1 [Hydra vulgaris]
Species Candelabrum cocksii · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQNNT00000023839

ATGGTAAACAATTTTCGTACTATGGATGAGTTTGGATTTGTCGGAGAAAATTTTCCTGGCAATGCTGCTGGTTTTAACAATGCTATGCCTACACAAATTCCACAGGGTCCTCAAATCCCTCACGGGCAAATGCCAGaAAACATACAGATTAGTATGGAGCAGCACATCCAGCAAACGAACGACCGTTTACAGTGCATTCGCAGGGATCTAAGTTCGCTAAATACATTTCAAAGCGCTGCTCGTGAACTTCTTGAATGGTGTGGCGATGCCAGAGCTTTTCAAATGTCTTACGAACAAAACCTCATGGCTTGTCTCACTATTGTGAGTAAAATTGCGCCAATGCAAGGGTATGACCTGGATCTAGGTTACAGATTGTTGGCCGTTTGCGCTGCTCACCGTGAAAAACTCTCTCGGAAGTCGTCAAGCATGCTCTCATGTTGGTGTGAGGAACTTGGTAGGTTACTTCTTATACGACGTCAACGAAAGTCAGATGTGAAGCCGTTTGCTAATTCAATGAAGAACGTTACAACTCCAATACCACATGGTGACAACACCATTATGTGGCAACCTAACAACCCGCAACAGACAAACGTTTCTGTTTCCGTATCCTCTGTCTGGGGAGTTTCCTCGGCTCAAACTAACGCCAACTCTATGATGACGATGCGGCAAGCAAACAATAACTCAATGGCGCCCGGCGTGAGCCCCCCAATGAACCAGTCTTTTGATCCGAACCTGGCACCAAATGGTATGCGTGGAAACGAAATGCCAAACATTCAAACTATGCACGGCATGAATAACTTCCAACGACAAAACAGCATGAACTTCAATCAACCGAACAATGGTCAGTCAAACCAGTCAAATAACTTTCAGCAAAACAATTCCAACTGTCCATTGCCCGCGGCTGCAGCAGCTGCTGCGGCTGTTGCTGCCGCCGCTGCTACAGCAACAGCCACTGCCACAGCAACTGCCACTCTTCATATGCAAGAACAGCCTGATCAGATGAACAATAAtgGCGAGTTTATGGATACGCAGCAATATCAAGTGCATGGTCAAACACAGTTTCAAGCTCGTGGTGGTATGAATAACAATATGAGCCGGCAAATGTACAAGCCAATGGGATCATACATGGGTGGAGCGCCCAACATGAACCCGTATATGACTCAGCAGAGAAACATGTATGGAATGGGACAACAGCAAATGCCAGGAAACTTAAGTGCACAAATGGCCCATCGCAATATGATGAGGTACCCAGTGCCTCAGATGAAACGTTCTCCTATGATGCCATTCAACCAGCCCATGATGGGGGGCAGTCCAATGACGCCGGAATCACCTTCATCACAGTTTGGGCCGTTTGGACCAGGAATGGGCAAAACCGGCCCCTTTCCAACTCATTATCAGCCTCACGGGTACAATGGCGGATTCGGACAAAATATGGGTGGTCCAATGAATATGAACAGTGTAGGTATGGCAGGCAACATTCCTAATAATATGGGGATGCCTCCTCAATACAACGCAGTGAATAACATGAACAATACCATGGGTAACATGATGGCGCAACAAACAGACGGAATACAACCAGTAGCTGTTCCACGGAGACCTAGCACGTTACAATATCCTCCAACCCAGTCCCCTAATAATAGGTATATGTCGATATGTGATTCGCCAGCCAGTACTGTGGATGTGAAACCGCAGATTGGCGGTGGTGGTGTGTCTCAACCAATGAAAAACATTCCTAACGTACCAAATATAGGCGCTAACACGCCTGATGTCAAACCGCAAATAAAACCAGACAAAGATTGTTTGCGTTTAACGTTCAGCGTTGCAAATGGCAGTGTTCTTTTGCCCTTCCGGCTAGAACACAACCTCGCGGTCAGCAACCACGCCTTCCTTTTGAAACCTGTTATATACCAGACACTCATGAGCAGACCGGACCTGGAACTTCAGTTTAAATGCTATCACCATGATGACAAGGCCATGACAACCAACTGGCCGAACAGTGTTAGTGTTAGTGTTAACAACAATCCGTTGACGCTGGAACGCGGCGAGAGCAAAAACTCCCATAAGCCGTTGCTTTTGAAGAACGTCTGCCGACCTGGAAGGAACACCATTCAAATAAACGtcgttgtttgttgttgttCTCATCTGTTCGTCCTGCAATTGGTGCATCGTCCCTCTGTCAACACAGTGTTGCAAGGGCTGCTCAAGAAGAGGCTCCTGCCAGCTGAACACTGTCTCAAAAAAATTAAGTATAACTTCAAGACGTCAGCCGCTAACGGCACGACGGTTTCAAACGACGAAGATGGTGTCGAGCAGACGGCCATCAAAGTGTCGTTGAAGTTCCGTATGAACAGTAAAGTGAGCAAGATCAGTATACCGGCCAGAGGTCCGGAATGCAAGCACATACAGTGTTTCGATCTGGAGACCTATTTAAAGTTGAACGTGGACGATGTAAACTGGAAATGTCCCGTGTGCAACAAAAGTGCTGTGTTAGAGGGACTGGAGGTTGATCAGTATCTATGGCAGATCATCACCACTTTGACCAAAACAGACGTAGAAGAAGTGACCATCGATTCCAGTGGCTCGTGGAAACCTGTTTCTGTGAAGcaggaaataaaacaagaagagATGAGTCCACCGTGTCCGGGCGGGCCATCTCCTAAGCGAATGAAATCAGTTGACATCGCCATATCGTCTCCGATGTCCATCACTAATCCATCGACGCCTGGTTCTTACAAGCCACCGACACCTGCATCGTGTAGCAGCGTTAAAACACCTGGCACGCCCGTTTCCAGTAGCGAGCTGAAGTTTATCGTGCCGTCCTCTTTAACATCGCAACCGCAGTTAATTCGCCAGCAGAGTCTACCAACCCCCGTCACCAACCGCCCTGATGCCGCGTGCCACTTAACGCCTCCTGCGGGCGGTCCTCCAACATTAGTTCGGTCACCAGAAGCTCCCCACCCTTCCGCCACCCCCACATCAACACCCTCCACCGAACCATCCGGTAAACCTTCCGATGATTGGACGAACGCCGAGTTCACTCTCGACACCATGTTTCCCGTGGCAGACGCTGATCCTGTCGTCGACAGTCAAGAGGAAAACAATTTAGACGTTATACCTGGCAGCCTCGACACGAACGAGCTCCTATCGTATTTAGGGCCGCCAGATCTTCCTTCCGAGGATCTCATCCTCAGCATGTTTGACGGTATCAATTCGGACGCAACGCCTAGAAGTACGGAACTTATATGA

Transcript

ENSQNNT00000023839

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9ULJ6	Zinc finger MIZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZMIZ1 PE=1 SV=3
Q6P1E1	Zinc finger MIZ domain-containing protein 1 OS=Mus musculus OX=10090 GN=Zmiz1 PE=1 SV=1
Q8NF64	Zinc finger MIZ domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZMIZ2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001568 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18028 all species →	Zmiz1_N	Zmiz1 N-terminal tetratricopeptide repeat domain	Repeat	Interproscan
PF02891 all species →	zf-MIZ	MIZ/SP-RING zinc finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR040797 all species →	Domain	Zmiz1, N-terminal tetratricopeptide repeat domain	Interproscan
IPR004181 all species →	Domain	Zinc finger, MIZ-type	Interproscan
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10782 all species →	ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000790 all species →	Cellular Component	chromatin	Interproscan
GO:0003712 all species →	Molecular Function	transcription coregulator activity	Interproscan
GO:0006357 all species →	Biological Process	regulation of transcription by RNA polymerase II	Interproscan
GO:0016925 all species →	Biological Process	protein sumoylation	Interproscan
GO:0030374 all species →	Molecular Function	nuclear receptor coactivator activity	Interproscan
GO:0061665 all species →	Molecular Function	SUMO ligase activity	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K22403	ZMIZ; zinc finger MIZ domain-containing protein	-	Transcription	-	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Candelabrum cocksii tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Candelabrum cocksii, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →