Gene detail

Detailed information of ENSQNNP00000023486.1 in Candelabrum cocksii

Genomic Location: chr1:5027057...5031023
NR annotation: AAV97963.1, protein-tyrosine kinase, partial [Hydractinia echinata]
Species Candelabrum cocksii · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQNNT00000024349

ATGGAAGTAGTCAAATATCGAGCGAACGTTAAATGCGCCGGCAACAAGTTAGATGTTAAGACGCCAGGTGGTAAACCGTCCGTTATTCGTTCGAGTACTGGGGATGAGATTCTAActgttgtcaatcatttggGCTACGGTAGGAAACCTTCTCACGGGTTAAATAAATTACTGCGAGAAATGAGGGAAGGTTtcgatgaaaataaaaagagcAACGTGGATGCAACTCGTAAAGCCAGTTTACCGTGCACATTGGCTCTAAAAGAATCTAACGTCGACGTGAAAAGCGTCGTTAACAAACTGACGTCACTGATGTGTGATTTGGAGAGAATCTTTGAAGTGAACACTATTAAACAGCTGCCCACGAAACACTGTCGGCGTAATGGTGCTGTAGACGGTGACTGTAGCGTGTTGTTGGAGAGTGTTCTTACATTAGAAAATAACACGAATCTATCAAATAATAACGCCAATGAATCTTTGACGGTAGCTGAAAAACGTAAAAGAAGAGTTGGAGGAAAGAGTTTTCTACAAAGTGACAATATGATAGCAGGTATTTCTTCGAACAAGATTACAAAACATTTGCCCGGGTACATTGATAAGCGTAAGAAAGATCTCCCAAGGATGAAATCGTTAGTTACGGAAGAAGAACCTTTGTACACAGTTATTGCTGATTTCCAGGAGATTAAGAGCTCGTTGGCTACGGAAGAAGAACCTTTGTACTCAGTTATTGCTGATTTCCAGGAAATTAAGAGCCATGCCACTGCGACACATGAAGAGAACAGAATATGCGATGAGACAGTTACTTATGCTGTTATAGATGATATTGTTACAAGTGTAGAGCGACACGTGGCATTAGATGAAAACGACAGATTAATTGCAGTTAGTAGTACGCATATCAGTAGAACGCGGTCAGTCGATTATCTTTACGCTCAAAAGATTTCTGCCGCTCATGAAATATCTCTAAACGACAGCATGTTGCATACAACCACTCATCACGTGACGTTGTGTCGACGTCTGAAAATGTTGGAAGCCAGTTACGGCGTGAGCCTTAAGAAACAGTTGCACGGCCTTGTTAaacagaaaatgaaaatgttaaaTGTAGCGGGGTGCGTGTATTGTATGTACTCGTTCTACGAAAAACAGAAACGAGAAGCCGACGAGAAAGCACGTCAAATACGCAAAACGCTCGAAGAACAAGAAACCATGCAAATGAAGTTGAATGAGCAGCGTCAGCAGACGGAAGCGGACAGTCAGTGGTTGGAAGTGGAGGATAACAAAAGCTACGCCGCCGATCCTTCTCACGACGGCAAAGTGAATGCAGGGTTCGCCAAGACTTCAAACACATCCGACTCTGAACAGTTAGGTTATGACTTGTACGAGGAAGATTTTGCTCGCGATGTCCTCGAACAAAAACTGCTAAAGAAAAGTTCATCTCCGTTGCGAAGAAGCGCGCCAATATGGAATGTCGACAAAGAATTAAGTACGAAAAGGCAACCATCCCCGTTGCTGCGCGACACAACTCCGGAAGAAAAGCAGCCGACCTCTTCATCATCGGAAGAAACGACGACCGCTGTAGCCACCTCGTCTCAAAGCATTGTGCGCAGCAATTCTCTGGGTGCTAGCGACCAGTACGCGAAACCCATCAAACCGACCACCATTGATAAGACGCGCAGTCAGACTGTCCACGGAGGTACTCGGGGAACCGTCGCAGCTAATATCGTTGACTTAGAGCGCGTCTACCAACTCACCACCAGTGTGGTGAAGTCAGTGATTGAGCTGAACACTGGAGTGCAACATGCTCAACCCGAAGAATTCCTTGATCTTGTTAAGGTGGTCGGTTTAAATCTACGCGATCTGCTTGCCGAAGTAAATTCAGTCACTTATAAAGAGATTGAAATGGCACGGAAGGTTCTTTCATCCGACATGGCCGAGTTGATCAGTAAAATGAAACAAGCGCAAAAATATGCGGGTACAACACTCGACCAACAGAACAGACGGAATATGTTAGCTGCCGCGCATGCGCTAGCTATTGACGCTAAAAATCTTTACGACACGTTCTCGAAATTAGAGAAGAACAAACCGAGTTGA

Transcript

ENSQNNT00000024349

GGTGATCGCCTATTGATTCGACACAAACGCATTGCCGTGGGGTCATCCTGGTATATTTGCACATGATATCTTAAGACGTTTTGTCTGAATTGCACTCGGCGCTGATAATAGCAGTTTATTTGTGATGAACAGATTCAATCGTTTAATAAGCTGCTTAGCGGAGGACAATAGCAGTTCCCACGATGACGATAAGAAACGAGTTTCTGTATGTAAGAAGTGTTTTACGAGGCTAGTCACAGGTGCTTGAaaaacatgacttccactctGAAGTAAAGGTCGTGTGAGACTCCAGAGGTATAATGGAAGTAGTCAAATATCGAGCGAACGTTAAATGCGCCGGCAACAAGTTAGATGTTAAGACGCCAGGTGGTAAACCGTCCGTTATTCGTTCGAGTACTGGGGATGAGATTCTAActgttgtcaatcatttggGCTACGGTAGGAAACCTTCTCACGGGTTAAATAAATTACTGCGAGAAATGAGGGAAGGTTtcgatgaaaataaaaagagcAACGTGGATGCAACTCGTAAAGCCAGTTTACCGTGCACATTGGCTCTAAAAGAATCTAACGTCGACGTGAAAAGCGTCGTTAACAAACTGACGTCACTGATGTGTGATTTGGAGAGAATCTTTGAAGTGAACACTATTAAACAGCTGCCCACGAAACACTGTCGGCGTAATGGTGCTGTAGACGGTGACTGTAGCGTGTTGTTGGAGAGTGTTCTTACATTAGAAAATAACACGAATCTATCAAATAATAACGCCAATGAATCTTTGACGGTAGCTGAAAAACGTAAAAGAAGAGTTGGAGGAAAGAGTTTTCTACAAAGTGACAATATGATAGCAGGTATTTCTTCGAACAAGATTACAAAACATTTGCCCGGGTACATTGATAAGCGTAAGAAAGATCTCCCAAGGATGAAATCGTTAGTTACGGAAGAAGAACCTTTGTACACAGTTATTGCTGATTTCCAGGAGATTAAGAGCTCGTTGGCTACGGAAGAAGAACCTTTGTACTCAGTTATTGCTGATTTCCAGGAAATTAAGAGCCATGCCACTGCGACACATGAAGAGAACAGAATATGCGATGAGACAGTTACTTATGCTGTTATAGATGATATTGTTACAAGTGTAGAGCGACACGTGGCATTAGATGAAAACGACAGATTAATTGCAGTTAGTAGTACGCATATCAGTAGAACGCGGTCAGTCGATTATCTTTACGCTCAAAAGATTTCTGCCGCTCATGAAATATCTCTAAACGACAGCATGTTGCATACAACCACTCATCACGTGACGTTGTGTCGACGTCTGAAAATGTTGGAAGCCAGTTACGGCGTGAGCCTTAAGAAACAGTTGCACGGCCTTGTTAaacagaaaatgaaaatgttaaaTGTAGCGGGGTGCGTGTATTGTATGTACTCGTTCTACGAAAAACAGAAACGAGAAGCCGACGAGAAAGCACGTCAAATACGCAAAACGCTCGAAGAACAAGAAACCATGCAAATGAAGTTGAATGAGCAGCGTCAGCAGACGGAAGCGGACAGTCAGTGGTTGGAAGTGGAGGATAACAAAAGCTACGCCGCCGATCCTTCTCACGACGGCAAAGTGAATGCAGGGTTCGCCAAGACTTCAAACACATCCGACTCTGAACAGTTAGGTTATGACTTGTACGAGGAAGATTTTGCTCGCGATGTCCTCGAACAAAAACTGCTAAAGAAAAGTTCATCTCCGTTGCGAAGAAGCGCGCCAATATGGAATGTCGACAAAGAATTAAGTACGAAAAGGCAACCATCCCCGTTGCTGCGCGACACAACTCCGGAAGAAAAGCAGCCGACCTCTTCATCATCGGAAGAAACGACGACCGCTGTAGCCACCTCGTCTCAAAGCATTGTGCGCAGCAATTCTCTGGGTGCTAGCGACCAGTACGCGAAACCCATCAAACCGACCACCATTGATAAGACGCGCAGTCAGACTGTCCACGGAGGTACTCGGGGAACCGTCGCAGCTAATATCGTTGACTTAGAGCGCGTCTACCAACTCACCACCAGTGTGGTGAAGTCAGTGATTGAGCTGAACACTGGAGTGCAACATGCTCAACCCGAAGAATTCCTTGATCTTGTTAAGGTGGTCGGTTTAAATCTACGCGATCTGCTTGCCGAAGTAAATTCAGTCACTTATAAAGAGATTGAAATGGCACGGAAGGTTCTTTCATCCGACATGGCCGAGTTGATCAGTAAAATGAAACAAGCGCAAAAATATGCGGGTACAACACTCGACCAACAGAACAGACGGAATATGTTAGCTGCCGCGCATGCGCTAGCTATTGACGCTAAAAATCTTTACGACACGTTCTCGAAATTAGAGAAGAACAAACCGAGTTGATCGCGGTGAACAACAATGATGGAAGGTAGCGAGTGAATTGAACATGCTCCAAGTCATCTAGAGCACTGGaaatatagtttttgttttctttaactcgatattttttaattttatttttcatcgcTAAACTATCTTCTGATACGAGCCCTTTCATTGAAGCCTGCTGCTGCTGTAAAACTTAGTTCTTGGttaagttgttttttaaaaacaaaacgatgATGATTCAGCAAAAACCTATTGTAAATACATAATCAATACACGTTTTTACGTCGTTGTATTCATCGTAGCAAGCGTCCAACCCTGAAAATTCATTCAATAAGTCTATCTATTAATACGCCTCAAACGAAAAACCATATCGCCTGCTTTATTGAAACCACTACAGGAAATGTGTACGGTCGTCATTACCACGTGTTGAGGCGCAACTAGACAGCTTCAACACCTTGAGGTATAAAAACAACACGACCTGTTATCGATAAAATGTCATAATTCAATAATATGTATTTCAGTTGATTCTTCCCATTAGTTACTGCTACAAAATCTACAAAATTACCACACAGAGAAAAATGGATGAAAAAGTGAAACTATCGTCTAGCAACAGGTTCTATCAGGATTTCTGCTGTGTCCTGGCTCGTGTTCAAAACCTGAAATGAGAAATGCTTCGTCGTCATAACTAAATGTTGTGCAGGTTGTCAAAAGAATAGGACAGGTTGCGGAAAGGTATTTCCTTCACAACACATTTCGAATTTTGTTGAGAGTATTTGCGAagagaatttgaaaaaaaaatcaaaggaataaaataaaaatcaaaaagtatAGAAATAGGTCTACAGTTATATCCACGGAGGGGAGGGGGTATCTTAACAAGGATATTAATTTACTAAGCATACTATATATCAACGAACGTTTTAAGCGCTGTTTTTGTGGAAATTTAGTGATCATCCAAGAACTTTAACTTTTACAGTTGAAAAGGtgcaaagaaatataaaatcttttcTCTGT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P34152	Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4
Q00944	Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2
O35346	Focal adhesion kinase 1 OS=Rattus norvegicus OX=10116 GN=Ptk2 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003173 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03623 all species →	Focal_AT	Focal adhesion targeting region	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036137 all species →	Homologous_superfamily	Focal adhesion kinase, targeting (FAT) domain superfamily	Interproscan
IPR005189 all species →	Domain	Focal adhesion kinase, targeting (FAT) domain	Interproscan

PANTHER

No PANTHER signature was recorded for ENSQNNP00000023486.1 in Candelabrum cocksii.

Gene Ontology

GO term	Category	Description	Source
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan
GO:0005925 all species →	Cellular Component	focal adhesion	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0007172 all species →	Biological Process	signal complex assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSQNNP00000023486.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Candelabrum cocksii tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Candelabrum cocksii, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →