Gene detail

Detailed information of ENSQPTP00000000843.1 in Actinia mediterranea

Genomic Location: :...
NR annotation: XP_031551243.1, 3-hydroxyisobutyrate dehydrogenase, mitochondrial-like [Actinia tenebrosa]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

ENSQPTT00000001119

GGAAAGTTCATAATCGTTCCTTAATACCGGAATTACCTTTAAATCCACTTCCTTAATGGTTTAGAATTTTTAAATGCTCGATGTACAACTTAACTGCACAGTAAACGTCTTAAACTTAATCAATCGTAAGACGTTGACCAGTACGACTCGCCAGGAACATAGGCCAATCAAGATTAATCTTCTAATTAGGTTTAGTTTGTTGCCGTTCTGGTTACCCgggaaaataaaatttcactgATCGAACAAAATGGCAACAGTTTTTCGAAGCAAACTTCTCATTTCCAAGCTTCCACCAAGGCTCCTACTGTCTCGATTCCTATCCAATGGAAGTAGCAATTCGGATTCTGCTATTGGGTTTATTGGACTAGGGAACATGGGAAGCCCAATGGCCAAAAATCTTATCAAGAGTGGTCATGAGATCATTATCTATGATGCTTCGCGGGATGTTATGGATGATTTAAAACAGAATGGTGCTGAGACAGCTCAAAGTCCTGCAGAAGTTGCATCAAGATCTAATAGAATAATTACCATGCTGCCATCAAGTCCAAATGTATTGGAAGTATACAGTGGAGAAAGTGGAATACTCAAGGAGGTCCAAGAAAATTCCTTACTTGTTGACTGTAGTACAATTGATCCAGCCATTGCCAAGGACATGAGTGAACTTGCATCTGGAAAAAAAGCAATGTATCTGGACTCCCCAGTATCAGGAGGCAtcacagcagcagcagcaggcACACTCACATTCATGGTTGGAGGTCAAAGTGAAGGATTCAAACAGGCAGAACAAATACTTCAGCACATGGGCAAGAATGTTATACATACAGGGCCTGTTGGAACTGGTCAAGCTGCCAAGATCTGCAATAACATGTTATTAGCTGTCAGCATGATTGGCACATCTGAAGCAATGAACCTGGGAATGAGTCTTGGTCTGGATGCCAAGATGATAGCTAAAATCATCAACAGTAGCTCTGGTCGGTGTTGGTCTAGCGAGCTGTACAACCCTTGCCCAGGAGTTGTTGAGGGTGTCCCATCTAATAATGATTATCAAGGAGGATTTATGTCAGCTCTCATGGCAAAGGATCTTGGTCTTGCACAAAACGCATCAACATCAACCAAGACTGCTACACCAATGGGTTCCTTGGCGCATCAGATCTTCAGGATTATGTGCAACAAAGGATATGGCCAGCTAGACTTTGGATctgttttcaaatttcttcAAGATGAAGGTTCCAAATGAGATCAAATTTGATAATTTAGGATAGAGATAAAACTTTTCTCAATTAAATTACACATTTTGCAACTGTAAAACATTTCTAAAAGAATGGCAGTTTTAAAATTTAGGGAGCTTAAAGTGTTTCAAAATGACAATTAAGTGATCCTCAAATAGCTTATTGCCCCAATGTAAAGTCCTCTTCTCTAGTACCTGTACATGTCAACTGCTCTTCACAGAGGGCCACTACCCAGACTACCTTCCAATCCAAAGGTGTAAACAATCAATTTAAAAGGtttaccactcttttcactgctacgcgctgatcgagacaacagtTGCAACAGGGAAATAGGCCAATACATTGCCGCCAACAGAGAATACAAAGGTACCaaccaatttatttgattgatggaAATGTATTGCCCAATTTCCCTGTCATGACTGTCGTCTCAATTTGTgcatagcaatgaaaagaTTAGTAAAACTGTGTGGAATATAGTATATTTGTCAGTATCGTTCGTATGGgtaatcattaattttttcccgCAAAGCTACTTGAAAAAGTGTATTTCATATTTATTGTAAGACATGCCAACATTTTCTTGCTTGACATTAATATCACATGAAATAAAACAGTGAAACTGAAGatacaaaaaaaactttgtttgTTGAATTCATGCACAAGGGAAGCAGTTCTCTGTTAAAATATACTGGGATCTGCATCTTTTATATGATTGCCTTCTCTAACAGCAATTTTATAAAACAGTTGCTGTTATAgttctattattattactattacatGTCACTATTACATGTATATGGTACAGGGTTGTATCAGTAACTGGTGATTAGTAAGGGACAGTGGTTTGACTTGCATGAATATACAGTATTTCTATCATGGTTTGCAAGCAATTCCAAGGGAGTCAAATGACATAGTAGCCATGTTGGTAGTATTAGCAAAGGACAACCATGTAACTTGCAAACATAGTATAAAATAAGGAATAAAACTACCTAGTTAGATTA

Protein

Uniprot

Uniprot term	Description
Q99L13	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hibadh PE=1 SV=1
P29266	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Hibadh PE=1 SV=3
P31937	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBADH PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF14833	NAD_binding_11	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	Domain	Interproscan
PF03446	NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011548	Family	3-hydroxyisobutyrate dehydrogenase	Interproscan
IPR013328	Homologous_superfamily	6-phosphogluconate dehydrogenase, domain 2	Interproscan
IPR002204	Conserved_site	3-hydroxyisobutyrate dehydrogenase-related, conserved site	Interproscan
IPR029154	Domain	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR015815	Family	3-hydroxyisobutyrate dehydrogenase-related	Interproscan
IPR008927	Homologous_superfamily	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	Interproscan
IPR006115	Domain	6-phosphogluconate dehydrogenase, NADP-binding	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22981	3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005739	Cellular Component	mitochondrion	Interproscan
GO:0006574	Biological Process	valine catabolic process	Interproscan
GO:0008442	Molecular Function	3-hydroxyisobutyrate dehydrogenase activity	Interproscan
GO:0016616	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0051287	Molecular Function	NAD binding	Interproscan
GO:0016491	Molecular Function	oxidoreductase activity	Interproscan
GO:0050661	Molecular Function	NADP binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00020	HIBADH, mmsB; 3-hydroxyisobutyrate dehydrogenase	EC:1.1.1.31	Valine, leucine and isoleucine degradation	ko00280	deepkoala