Gene detail

Detailed information of ENSQPTP00000004203.1 in Actinia mediterranea

Genomic Location: chr1:25672170...25676510
NR annotation: XP_031550724.1, EH domain-containing protein 3-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000005208

attattattattattattattattattattattagcaaTGAAGTAATAATAAAGCTCGTGATTATTATGAGTCATGAGTATTTGATCCCAACCTGGAAGTGACGTCATAAGATGTGACGTTGAGGCATGCGCAAAGGGAGGCGGAAGGGAGCGGCTTACTCGTTCAGTGATGACTTATATTAGTTTCCAAACGTAATAAGGGAAGTGTGAGATTGAAGAGCAAAAATCACCAAATTAACTCCATAATACCTCATAAAAACCCTCAGAGAGGCAAGACAAGGACCTAAACAGGCCTAACGATGTTTTCTTTCATGAGTAAGAGCGAAAGTGGCCGTAAAAACCCACAAGTTTTCGGGTCGGTGTTGGATGGCTTGAAAAAACTCTACATGAAAAATCTCAAACCTTTAGAAGATCAGTACTTGTTTAGCGACTTCCATTCACCTCCATTGACTGAACCAGACTTCCACGCTAAGCCTATGGTTCTCTTAGTAGGACAGTACTCTACAGGAAAGACCACATTCATTAAATATCTACTAGAACAAGATTTCCCTGGCATTAGAATTGGACCAGAGCCTACAACAGATAGCTTCATAGCTGTGATGCATGGAGACACGAGTCAAGTCATACCTGGGAATGCCCTTATAGTTGACCCAAAAAAGCAATTCCGCTCACTCAGCTCCTTCGGTAATGCTTTCTTGAATCGTTTCTGCTGCTCTGAGCTGCCAAATGCTGTATTAGAGAGTCTTACGATCGTAGACACCCCTGGAATCCTATCCGGTGAAAAGCAGAGTGTCGCACGAGGGTACGACTTCACCGGCGTCTTAAAATGGTTCGCAGAACGTTGCGATCGCATTATCTTACTCTTCGATGCTCATAAGCTTGATATTTCGGATGAATTCCAAAGAGGAATAGAGGTTCTTAAGAACTACGATGAAAAAATTCGCATCGTCTTGAACAAAGCAGACATGGTCACAACGCAGCAGTTGATGAGAGTCTATGGAGCCCTGATGTGGTCTTTGGGCAAAGTCATAAATACTCCAGAGGTTGCACGTGTATATATTGGGTCCTTCTGGAATCAGCCCCTACAGATTGACGACAATCGAAAATTATTCGAGATGGAGGCTACCGATTTGTTCAGAGATATGCAAGATTTGCCCAAGAATGCAGCTCTGAGGAAACTCAATGATTTCATCAAGAGAGCTCGCCTAGCAAAGGTACATGCCTATATTATTTCTGAGCTAAAGAATCAAATGCCATCTATGTTTGGcaaggagaaaaagaaagaacagcTCATCAAGAACCTGATAGATATCTACAGTAAAATCCAAGCAGAACACAACATCTCTCCGGGAGACTTCCCATCACTCTCCAAGTTTAAAGATCAACTTCAGCACCatgatttttcaaagttcagtGGGATGCGCACCAAACTGATTCAAAATCTGGACAGCATGCTTGCTAACGACATCCCAAGATTAATGCAAATGATCCCCCAGGAGCAGCATGATGACGCTGACAAACCTCCTGTTACAGGTGGCGCCTTTACCATCAGACATTCAACAAATAACCCATTCTCTCAAGGAGCTTGTGAGGGAGTTGCATTGGGTGCAGGAAGTAATGAATGGATTGTAAGAGATTTCCAACCTGTCTATGACAAGATTTTCGAGTCTTTAAATCCAGCAGATGGGAAAGTTTCTGGTGCCAAGGCGAAGAAAGAAATGGTCAAATCCAAACTACCAAATACTGCTTTGGGTCGCATTTGGAAGCTTTCTGATGTTGACCGCGATGGATGCCTAGATAGAGATGAATTTGCTCTCGCAATGTACCTGATCAAAATCAAACTAGAAGATAATGATATTCCAGAAGAACTACCCAACCACTTGATACCACCATCTAAAAGGCAAAACAGTCAGGCTGATCCAATTGAGTATGACTAAGCTTTTTTAGGGAATTCTTAAAAACTGTATGTTGAACGTTTACAGTGTGAACACAATAACCAGGACCACTTTTACAATGCTAGCCAATCACAACATAgaacgaaaacaaaacaatcaaactgaaccaatcagaagcaaGCATCTATGCCTTGATATCTGAGAAATAACATTAAGATATTAACAACAACTTTGGGAATGAACATGAATGAAagattgtgattggctgaggtTAAGATGCGAAATacccaaattatttttttgtgcaATGCGTTTCCAGCTTATTCTACTTTAAAACAATTGGTTGATAAGCACTTAATACCTGTTAGTTATGATACTGATTTTGCCCTCTTttcttctgattggctgaagtTTTCACTATACAAAGTGATTGACTTACTTTGTAAATGTAGTCCTGGTTAGTGAGTGGTCAATGCTGTAAGATACTTgtgtatattattttattgaatttaagTGATTAGTTCGAATAAGTAAGAATATTCTATACATAACTTCTTAGTTGAGTTTGGCAGGTTGACAgttttaattataataattatgatgatgatgacagggcagaaaaacgggtTCTACTTTCTACGTTTATGCGTtaataagctttatatttaataaacaggctcttttggggctgattaacaaaataccaaaatttggagaaatttaaggaatgcgtatttgagatataacgcccTGAACGTTGGGAGAGAGGATGTTTTAATcagcacaaaaactaacatTTTCGCTAATACCTCGAAGTAGAATTGCTCGAGGTTAGCAGAATTTTGTGtaaagtttaaaaaacaaGAGACATGAATGAAACACTAAGCTTTTTTTAgcatgaatttttttctttatctctcaTTCATGCTAAAAAAAGTTTAGTGTTTCATTCATGTCTCttgttttttaaactttaCACAAAATTCTGCTAACCTCGAGCAATTCTACTTCGAGGTATTAGCGaaaatgataaagaaaaaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9NZN3	EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2
Q9QXY6	EH domain-containing protein 3 OS=Mus musculus OX=10090 GN=Ehd3 PE=1 SV=2
Q8R491	EH domain-containing protein 3 OS=Rattus norvegicus OX=10116 GN=Ehd3 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007257 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18150 all species →	DUF5600	Domain of unknown function (DUF5600)	Domain	Interproscan
PF16880 all species →	EHD_N	N-terminal EH-domain containing protein	Family	Interproscan
PF12763 all species →	EF-hand_4	Cytoskeletal-regulatory complex EF hand	Family	Interproscan
PF00350 all species →	Dynamin_N	Dynamin family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000261 all species →	Domain	EH domain	Interproscan
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR040990 all species →	Domain	Domain of unknown function DUF5600	Interproscan
IPR031692 all species →	Domain	EH domain-containing protein, N-terminal	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR030381 all species →	Domain	Dynamin-type guanine nucleotide-binding (G) domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR045063 all species →	Domain	Dynamin, N-terminal	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11216 all species →	EH DOMAIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006897 all species →	Biological Process	endocytosis	Interproscan
GO:0016197 all species →	Biological Process	endosomal transport	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12476	EHD3; EH domain-containing protein 3	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →