Detailed information of ENSQPTP00000004616.1 in Actinia mediterranea

Genomic Location: chr1:2654740...2686318
NR annotation: XP_031559765.1, E3 ubiquitin-protein ligase UBR3-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
F1QJX5E3 ubiquitin-protein ligase ubr3 OS=Danio rerio OX=7955 GN=ubr3 PE=2 SV=2
Q5U430E3 ubiquitin-protein ligase UBR3 OS=Mus musculus OX=10090 GN=Ubr3 PE=1 SV=3
Q6ZT12E3 ubiquitin-protein ligase UBR3 OS=Homo sapiens OX=9606 GN=UBR3 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002596 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02207
all species →
zf-UBRPutative zinc finger in N-recognin (UBR box)FamilyInterproscan
PF00620
all species →
RhoGAPRhoGAP domainDomainInterproscan
PF14555
all species →
UBA_4UBA-like domainDomainInterproscan
PF18995
all species →
PRT6_CProteolysis_6 C-terminalDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR003126
all species →
DomainZinc finger, UBR-typeInterproscan
IPR039164
all species →
FamilyE3 ubiquitin-protein ligase UBR1-likeInterproscan
IPR000198
all species →
DomainRho GTPase-activating protein domainInterproscan
IPR008936
all species →
Homologous_superfamilyRho GTPase activation proteinInterproscan
IPR044046
all species →
DomainE3 ubiquitin-protein ligase UBR-like, C-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR21497
all species →
UBIQUITIN LIGASE E3 ALPHA-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan
GO:0000151
all species →
Cellular Componentubiquitin ligase complexInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0016567
all species →
Biological Processprotein ubiquitinationInterproscan
GO:0061630
all species →
Molecular Functionubiquitin protein ligase activityInterproscan
GO:0071596
all species →
Biological Processubiquitin-dependent protein catabolic process via the N-end rule pathwayInterproscan
GO:0007165
all species →
Biological Processsignal transductionInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11978UBR3; E3 ubiquitin-protein ligase UBR3EC:2.3.2.27
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
TOP