Genomic Location: chr10:8211912...8216924
NR annotation: XP_031554327.1, E3 ubiquitin-protein transferase MAEA-like isoform X1 [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
| CDS |
| ENSQPTT00000006607 |
| Transcript |
| ENSQPTT00000006607 |
| Protein |
| ENSQPTP00000005432.1 |
| UniProt accession | Description |
|---|---|
| Q7L5Y9 | E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 |
| Q4R9A8 | E3 ubiquitin-protein transferase MAEA OS=Macaca fascicularis OX=9541 GN=MAEA PE=2 SV=1 |
| Q5R532 | E3 ubiquitin-protein transferase MAEA OS=Pongo abelii OX=9601 GN=MAEA PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006933 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|U-box · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF10607 all species → | CTLH | CTLH/CRA C-terminal to LisH motif domain | Domain | Interproscan |
| PF13445 all species → | zf-RING_UBOX | RING-type zinc-finger | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006594 all species → | Conserved_site | LIS1 homology motif | Interproscan |
| IPR044063 all species → | Domain | Gid-type RING finger domain | Interproscan |
| IPR006595 all species → | Domain | CTLH, C-terminal LisH motif | Interproscan |
| IPR045098 all species → | Family | Fyv10 family | Interproscan |
| IPR024964 all species → | Domain | CTLH/CRA C-terminal to LisH motif domain | Interproscan |
| IPR027370 all species → | Domain | Zinc finger, RING-type, eukaryotic | Interproscan |
| IPR013144 all species → | Domain | CRA domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12170 all species → | MACROPHAGE ERYTHROBLAST ATTACHER-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0034657 all species → | Cellular Component | GID complex | Interproscan |
| GO:0043161 all species → | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K18624 | MAEA, EMP; macrophage erythroblast attacher | - | Cytoskeleton proteins | ko04812 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
