Genomic Location: chr13:12656978...12659631
NR annotation: XP_031570618.1, DNA polymerase epsilon subunit 3-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
| CDS |
| ENSQPTT00000010277 |
| Transcript |
| ENSQPTT00000010277 |
| Protein |
| ENSQPTP00000008248.1 |
| UniProt accession | Description |
|---|---|
| Q642A5 | DNA polymerase epsilon subunit 3 OS=Rattus norvegicus OX=10116 GN=Pole3 PE=1 SV=1 |
| Q3SZN5 | DNA polymerase epsilon subunit 3 OS=Bos taurus OX=9913 GN=POLE3 PE=2 SV=1 |
| Q9NRF9 | DNA polymerase epsilon subunit 3 OS=Homo sapiens OX=9606 GN=POLE3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0008590 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00808 all species → | CBFD_NFYB_HMF | Histone-like transcription factor (CBF/NF-Y) and archaeal histone | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR009072 all species → | Homologous_superfamily | Histone-fold | Interproscan |
| IPR051377 all species → | Family | DNA Polymerase Epsilon Subunit | Interproscan |
| IPR003958 all species → | Domain | Transcription factor CBF/NF-Y/archaeal histone domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46172 all species → | DNA POLYMERASE EPSILON SUBUNIT 3 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0046982 all species → | Molecular Function | protein heterodimerization activity | Interproscan |
| GO:0006272 all species → | Biological Process | leading strand elongation | Interproscan |
| GO:0006974 all species → | Biological Process | DNA damage response | Interproscan |
| GO:0008622 all species → | Cellular Component | epsilon DNA polymerase complex | Interproscan |
| GO:0008623 all species → | Cellular Component | CHRAC | Interproscan |
| GO:0031490 all species → | Molecular Function | chromatin DNA binding | Interproscan |
| GO:0031507 all species → | Biological Process | heterochromatin formation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02326 | POLE3; DNA polymerase epsilon subunit 3 | EC:2.7.7.7 | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
