Genomic Location: :...
NR annotation: XP_031568203.1, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [Actinia tenebrosa]
| CDS | |||||
| ENSQPTT00000014798 | |||||
| Transcript |
| ENSQPTT00000014798 |
| Protein |
| ENSQPTP00000012042.1 |
| Uniprot term | Description |
|---|---|
| P60483 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Canis lupus familiaris OX=9615 GN=PTEN PE=2 SV=1 |
| P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Homo sapiens OX=9606 GN=PTEN PE=1 SV=1 |
| O08586 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Mus musculus OX=10090 GN=Pten PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF10409 | PTEN_C2 | C2 domain of PTEN tumour-suppressor protein | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR014020 | Domain | Tensin phosphatase, C2 domain | Interproscan |
| IPR029023 | Domain | Tensin-type phosphatase domain | Interproscan |
| IPR016130 | Active_site | Protein-tyrosine phosphatase, active site | Interproscan |
| IPR029021 | Homologous_superfamily | Protein-tyrosine phosphatase-like | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR051281 | Family | Dual-specificity lipid and protein phosphatase | Interproscan |
| IPR003595 | Domain | Protein-tyrosine phosphatase, catalytic | Interproscan |
| IPR000387 | Domain | Tyrosine-specific protein phosphatases domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12305 | PHOSPHATASE WITH HOMOLOGY TO TENSIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016311 | Biological Process | dephosphorylation | Interproscan |
| GO:0004725 | Molecular Function | protein tyrosine phosphatase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006470 | Biological Process | protein dephosphorylation | Interproscan |
| GO:0008285 | Biological Process | negative regulation of cell population proliferation | Interproscan |
| GO:0014065 | Biological Process | obsolete phosphatidylinositol 3-kinase signaling | Interproscan |
| GO:0016314 | Molecular Function | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | Interproscan |
| GO:0042995 | Cellular Component | cell projection | Interproscan |
| GO:0046856 | Biological Process | phosphatidylinositol dephosphorylation | Interproscan |
| GO:0048870 | Biological Process | cell motility | Interproscan |
| GO:0051896 | Biological Process | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01110 | PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | EC:3.1.3.16 EC:3.1.3.48 EC:3.1.3.67 | Protein phosphatases and associated proteins | ko01009 | deepkoala |