Genomic Location: not available for this species
NR annotation: XP_031565143.1, rap guanine nucleotide exchange factor 6-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families
| CDS |
| ENSQPTT00000017061 |
| Transcript |
| ENSQPTT00000017061 |
| Protein |
| ENSQPTP00000013845.1 |
| UniProt accession | Description |
|---|---|
| Q8TEU7 | Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 |
| F1PBJ0 | Rap guanine nucleotide exchange factor 2 OS=Canis lupus familiaris OX=9615 GN=RAPGEF2 PE=1 SV=2 |
| Q9Y4G8 | Rap guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=RAPGEF2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002715 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00617 all species → | RasGEF | RasGEF domain | Family | Interproscan |
| PF00618 all species → | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00788 all species → | RA | Ras association (RalGDS/AF-6) domain | Domain | Interproscan |
| PF00595 all species → | PDZ | PDZ domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001895 all species → | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR000159 all species → | Domain | Ras-associating domain | Interproscan |
| IPR000595 all species → | Domain | Cyclic nucleotide-binding domain | Interproscan |
| IPR001478 all species → | Domain | PDZ domain | Interproscan |
| IPR000651 all species → | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR014710 all species → | Homologous_superfamily | RmlC-like jelly roll fold | Interproscan |
| IPR018490 all species → | Homologous_superfamily | Cyclic nucleotide-binding domain superfamily | Interproscan |
| IPR019804 all species → | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR036964 all species → | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR023578 all species → | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR036034 all species → | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR008937 all species → | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 all species → | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 all species → | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 all species → | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0016324 all species → | Cellular Component | apical plasma membrane | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K08018 | RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2 | - | Tight junction | ko04530 | deepkoala |
