Gene detail

Detailed information of ENSQPTP00000016003.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031559628.1, NADPH oxidase 4-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9NPH5	NADPH oxidase 4 OS=Homo sapiens OX=9606 GN=NOX4 PE=1 SV=2
Q9JHI8	NADPH oxidase 4 OS=Mus musculus OX=10090 GN=Nox4 PE=1 SV=1
Q5R5C5	NADPH oxidase 4 OS=Pongo abelii OX=9601 GN=NOX4 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000994 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01794 all species →	Ferric_reduct	Ferric reductase like transmembrane component	Family	Interproscan
PF08030 all species →	NAD_binding_6	Ferric reductase NAD binding domain	Domain	Interproscan
PF08022 all species →	FAD_binding_8	FAD-binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013130 all species →	Domain	Ferric reductase transmembrane component-like domain	Interproscan
IPR013121 all species →	Domain	Ferric reductase, NAD binding domain	Interproscan
IPR013112 all species →	Domain	FAD-binding 8	Interproscan
IPR039261 all species →	Homologous_superfamily	Ferredoxin-NADP reductase (FNR), nucleotide-binding domain	Interproscan
IPR050369 all species →	Family	Respiratory burst oxidase/Ferric reductase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11972 all species →	NADPH OXIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006952 all species →	Biological Process	defense response	Interproscan
GO:0016175 all species →	Molecular Function	superoxide-generating NAD(P)H oxidase activity	Interproscan
GO:0042554 all species →	Biological Process	superoxide anion generation	Interproscan
GO:0043020 all species →	Cellular Component	NADPH oxidase complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K21423	NOX4, RENOX; NADPH oxidase 4	EC:1.6.3.-	AGE-RAGE signaling pathway in diabetic complications	ko04933	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.