Gene detail

Detailed information of ENSQPTP00000017807.1 in Actinia mediterranea

Genomic Location: chr16:6477817...6495834
NR annotation: XP_031555898.1, mitotic spindle assembly checkpoint protein MAD1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQPTT00000021811

ATGATAGTAAGAGCAAGATTCTACATTCTTTTTGGcaaaataaaacagttaaaGAGCCGAAGAAGGACCAGGGGTGATCAGAACTACATAAATATGGACGTGGATATGAATTTCTTAAGGACTCCAGATGATAGTACGGCAGTTGTTAGGATAATGGGAGAGTTTGATCAGTTTTTAACTGATTCTGAAGTGAGTGGAATTGCGGATCCAAAGTTGCGTTTGACATTTGATGATGATACAGAACAGATACGACCTACAAGAAGAGCAACAAAGACAATAACTTACCAGAAACCCTTCAGAAGTCTAGCCCGATCACAAAGCAGTAGTGTAGTGACTGAGAAAGACCGTGAGAAAGATGTGGAGATTATTAAAAGTCATAGTAAGATAGCTCATCTTGAGAGCCAGTTGTATTCAATGGAGTCTTCGAGAAAGAGAGCTCGGGTAGAGCAAGACATGGAGTGTGAGATCCAGCGACAAGAACTGAATAAGAAGTCTGAGAAGATGGAGGATTTGATGAAGAGCGTGCAGTATGCTTTGGATCAAGAGAAGCAGGCTAAGGAACAGCTCAGTGACATCAAAAAAGAGTATGAGTTTTACAAGAACAAAGCTGATAAGAAGATTCAGAATTTGCAGAGGGAAAAACTAAAGCTAAGTTCAGAAATAGAGGAGGTTAAAGAAGATAATGGCCGGAAACAACTAGACCTGCGCAATGCACTCACAAGACAAGAGGcagaaaatattataattcAAAACAAACTGGATGAATCAGAAGCCAAGCTGGAAACTTTCAAGAGACGTTATAGTGAAGCTTCAAAACAAGTAGTTGAAATAGAAGAGTTGAGGAACACAGCAAGAAATGCCACTCTCAGGGTTAAGGAATTAGAACAGCAACTGTCCAGGCAAGAAGATGCCGCAAGCATCGCCATGACAATGCAGAGTCAGCTAAGTAGATACCGTGAACTAGAAAAGCAAAACTTAAAGCTTGAAGAAGACAACAGATATTACAGAGAAACAAATGAAAGTAACCTGTTGTTGAAAGAACAGAGAGACAGCATGGCTGCCAAGCTGAAGAGAGCTGAGGAGAGAATTAAAGATCTGTCTATCTtggaatttgaaaatgaaGATCTAAAGAAGAGAATAAAGCATTGGGAGGTAGAAGATGCGTCAGGTAACACCAAGACAGCATCACCTGTTCAGTTGACCCATGAGATAGcaaaactacaaaaaagtCAAGTGGTGTTGTTAGAGCAGCAGAGTGATCTGAAATCAAGTTCACAGATTCATGAAGCTGCTCGTCAAAAGGCAGAAACTGAGTTGTCTGCTGCACTAAAGGAACTGAATACATTACAGGCAAGTGAATCTAAGCACAAAGAACTTTACCAAAGATTGCAAAGGCGCTTGGTTCTTATTACTGCTGAAAGAGATGGCTTCCGTCGTATCCTTAATGTGTTTGATAACAACTTGTCTGCAAACTATGACTCACAGCTGCGGGATCGTGTGCAGGAGgcAGAGGAAAGACTGGCTTCTTATAGCAAACATGTTGAAGCCGTTGAAaGTGAAATAAGTCAAGCAAAGGATCAGCTTGCTTCTCAAAAGACGATAATCTTAGAGTTGGAAAGACAGTTAAAGGAGGAGAAATCAAAATGTGCCAGCAGGTCGACTGTATCAACCGCCACAGATAACGAAGCCAAAGCAGAAATAAAACGACTTGgagaagaaaatatgaaacTTGCTGAACAACTGGAAATATATGAACTACGGAAAGAACAAATGCACATACAGGGATATTACGACCCTACGAAGACCAAGGTCCTTCATTTCTCGATGAACCCAACGAGTTTTGCTCGACAGAAAAAAgtcgaagaaatagaaaaactaCGCAAAGAAAATGATTCTCTTCGGCTGAAAATCCAAGCCCTGGAAGGTGGGAAATTGccggcttctagtagcacagCAGCTGATAGCCTACAGACCAGTCCAGAGATAAGTGCCAGTACAACTAAGCAAGTAGAAGAAGTCAAGGCGCAACTCTCGTCTTCAGAACTGAGAAACCAACGTCTGAAAGAGGTATTTTCCAAAAAGATCCAAGAGTTTCGCGAGGCTTGTTATGCGTTAACCGGTTACAAGATAGACGTCCTGCGAGACAAGCAATACAGACTACAGTCCATGTATGCTGAGAGATCTTCCGATGACTTGCTATTCGAGAGCAATAGCAAAGGAGAGATGATGTTATTAGAGACGGACTTCTCGTCTCAGGTCCGAGACCACATCGAGACTTACCTAAGAAGAATGAACTCCATTCCAGCATTCCTTAGTAACGTCACTCTTGACTTGTTTAGTAAACAAACTACAACGATTGTCATCAACTAA

Transcript

ENSQPTT00000021811

gttcaGTTGTGTGTACATTTGGATCTGTCTGACTGAAGCGTCTTCAAAGTGGTTAAAATGATAGTAAGAGCAAGATTCTACATTCTTTTTGGcaaaataaaacagttaaaGAGCCGAAGAAGGACCAGGGGTGATCAGAACTACATAAATATGGACGTGGATATGAATTTCTTAAGGACTCCAGATGATAGTACGGCAGTTGTTAGGATAATGGGAGAGTTTGATCAGTTTTTAACTGATTCTGAAGTGAGTGGAATTGCGGATCCAAAGTTGCGTTTGACATTTGATGATGATACAGAACAGATACGACCTACAAGAAGAGCAACAAAGACAATAACTTACCAGAAACCCTTCAGAAGTCTAGCCCGATCACAAAGCAGTAGTGTAGTGACTGAGAAAGACCGTGAGAAAGATGTGGAGATTATTAAAAGTCATAGTAAGATAGCTCATCTTGAGAGCCAGTTGTATTCAATGGAGTCTTCGAGAAAGAGAGCTCGGGTAGAGCAAGACATGGAGTGTGAGATCCAGCGACAAGAACTGAATAAGAAGTCTGAGAAGATGGAGGATTTGATGAAGAGCGTGCAGTATGCTTTGGATCAAGAGAAGCAGGCTAAGGAACAGCTCAGTGACATCAAAAAAGAGTATGAGTTTTACAAGAACAAAGCTGATAAGAAGATTCAGAATTTGCAGAGGGAAAAACTAAAGCTAAGTTCAGAAATAGAGGAGGTTAAAGAAGATAATGGCCGGAAACAACTAGACCTGCGCAATGCACTCACAAGACAAGAGGcagaaaatattataattcAAAACAAACTGGATGAATCAGAAGCCAAGCTGGAAACTTTCAAGAGACGTTATAGTGAAGCTTCAAAACAAGTAGTTGAAATAGAAGAGTTGAGGAACACAGCAAGAAATGCCACTCTCAGGGTTAAGGAATTAGAACAGCAACTGTCCAGGCAAGAAGATGCCGCAAGCATCGCCATGACAATGCAGAGTCAGCTAAGTAGATACCGTGAACTAGAAAAGCAAAACTTAAAGCTTGAAGAAGACAACAGATATTACAGAGAAACAAATGAAAGTAACCTGTTGTTGAAAGAACAGAGAGACAGCATGGCTGCCAAGCTGAAGAGAGCTGAGGAGAGAATTAAAGATCTGTCTATCTtggaatttgaaaatgaaGATCTAAAGAAGAGAATAAAGCATTGGGAGGTAGAAGATGCGTCAGGTAACACCAAGACAGCATCACCTGTTCAGTTGACCCATGAGATAGcaaaactacaaaaaagtCAAGTGGTGTTGTTAGAGCAGCAGAGTGATCTGAAATCAAGTTCACAGATTCATGAAGCTGCTCGTCAAAAGGCAGAAACTGAGTTGTCTGCTGCACTAAAGGAACTGAATACATTACAGGCAAGTGAATCTAAGCACAAAGAACTTTACCAAAGATTGCAAAGGCGCTTGGTTCTTATTACTGCTGAAAGAGATGGCTTCCGTCGTATCCTTAATGTGTTTGATAACAACTTGTCTGCAAACTATGACTCACAGCTGCGGGATCGTGTGCAGGAGgcAGAGGAAAGACTGGCTTCTTATAGCAAACATGTTGAAGCCGTTGAAaGTGAAATAAGTCAAGCAAAGGATCAGCTTGCTTCTCAAAAGACGATAATCTTAGAGTTGGAAAGACAGTTAAAGGAGGAGAAATCAAAATGTGCCAGCAGGTCGACTGTATCAACCGCCACAGATAACGAAGCCAAAGCAGAAATAAAACGACTTGgagaagaaaatatgaaacTTGCTGAACAACTGGAAATATATGAACTACGGAAAGAACAAATGCACATACAGGGATATTACGACCCTACGAAGACCAAGGTCCTTCATTTCTCGATGAACCCAACGAGTTTTGCTCGACAGAAAAAAgtcgaagaaatagaaaaactaCGCAAAGAAAATGATTCTCTTCGGCTGAAAATCCAAGCCCTGGAAGGTGGGAAATTGccggcttctagtagcacagCAGCTGATAGCCTACAGACCAGTCCAGAGATAAGTGCCAGTACAACTAAGCAAGTAGAAGAAGTCAAGGCGCAACTCTCGTCTTCAGAACTGAGAAACCAACGTCTGAAAGAGGTATTTTCCAAAAAGATCCAAGAGTTTCGCGAGGCTTGTTATGCGTTAACCGGTTACAAGATAGACGTCCTGCGAGACAAGCAATACAGACTACAGTCCATGTATGCTGAGAGATCTTCCGATGACTTGCTATTCGAGAGCAATAGCAAAGGAGAGATGATGTTATTAGAGACGGACTTCTCGTCTCAGGTCCGAGACCACATCGAGACTTACCTAAGAAGAATGAACTCCATTCCAGCATTCCTTAGTAACGTCACTCTTGACTTGTTTAGTAAACAAACTACAACGATTGTCATCAACTAAGCACGTGATACAACACGTGTTACGACCACGTGATACAACCACGTGTATATCATGAACTCTATCCCAGCAATCCAAAGTAAAGTCAATCTTGACTTGTTTAGTAAACAAACTACGACGATTGTCATCAACTGAACACGTGAAACAACACGTGATGATCACGTGAATCTTATTGACTCTGCGGTCTCCCGTTGCTAAGTAACGTAACACTCGACTAAGTAAAGCAACATCAGAAATCAGGGTCAGGGCTTGTAATGTATATCCTTGTAATATCATTCAAGCTTCCCCCCTAAGAGGAGATCTCCCAATTCTGACCCGCCATTATGCAAAGATAGGTCTGAAACtgtatcaattttttttgtatgtacatattattattatatttgattGGGGATGACCTTGTTAAACTCATAGAACCTTTTATAAGCTAATAAAATATTGGCAACTACCTGTTTTTCAATTATTACAAGCGGGTAGGATCCTGGGTTGACGCTCTTATTGAATATCTCGTTGGCGAGATGATAACATCAACCCAGGTTCATTCACCTTCTGTAAGAATTAACTCAAAATGACTGAAACGTTTGGGTGTTATAGCGCACTATACCAAACATAATATTAAGGCATTTTGAGCTAATTCTCACTGAGATATTCTCTATTTGATAATGTGACTTTTTACAAGGATCCTGGCTTTACGTCATCACTTCATGATAGATTTCTATATTTAATATCTCGGCAACGAAAAgagatttcaaaaaaaaaaaaaaaaggaaaggccattctcatttattttataaggGCTTTGAACTCAAAAAGAGATCCCCGTTTAGGCTTGATAGGCACTTCAATATATTAACTGGAAAAGACCAATTGACTGAGTAACATCGTTCTTGCTATCGCTCGAGTTTGCCTTTTTCTAAAGAAAACTTCCGGTTGAAACgcgtaaaaaaattcaaggaaCTCGATGTATAGCTTTAAAGTGAGGACCCTCGAAC

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9Y6D9	Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2
Q80YF0	Mitotic spindle assembly checkpoint protein MAD1 OS=Cricetulus griseus OX=10029 GN=MAD1L1 PE=2 SV=1
Q9WTX8	Mitotic spindle assembly checkpoint protein MAD1 OS=Mus musculus OX=10090 GN=Mad1l1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005080 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF05557 all species →	MAD	Mitotic checkpoint protein	Coiled-coil	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008672 all species →	Family	Spindle assembly checkpoint component Mad1	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23168 all species →	MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0007094 all species →	Biological Process	mitotic spindle assembly checkpoint signaling	Interproscan
GO:0000776 all species →	Cellular Component	kinetochore	Interproscan
GO:0005635 all species →	Cellular Component	nuclear envelope	Interproscan
GO:0051315 all species →	Biological Process	attachment of mitotic spindle microtubules to kinetochore	Interproscan
GO:0072686 all species →	Cellular Component	mitotic spindle	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06679	MAD1; mitotic spindle assembly checkpoint protein MAD1	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →