Gene detail

Detailed information of ENSQPTP00000018301.1 in Actinia mediterranea

Genomic Location: chr17:6955649...6978853
NR annotation: XP_031572753.1, unconventional myosin-VI-like isoform X1 [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQPTT00000022481

ATGGATGGCGGACAGAAGATCTGGGTGCCTGATGTCGAGCATGGGTTTCGTTTAGGGACAATTCTCGATCTCGGAGCTGATGAAATAACGGTGGAACTTGATGGACTCAAAGGAAAGACTGTCACAGCTCCATACAACCGTGTCTTCCCGGCAGAAAAGGATAACTCTAAAGATGTCGAGGATAATTgTGCTCTGATGTATTTGAATGAAGCTACCCTTCTGAATAACCTTAGAGTCCGGTACAACAAAGACAAGATCTATACCTATGTTGCCAATATTCTGTTAGCCGTCAACCCGTATCATGATGTGAAAGAACTATACACAAAAGAGACTATCCACAAATACCATGGCAAATCACTTGGTACTCTTCCACCACATGTCTTTGCAATTGCTGATAAAGCGTACAGAGATATGCGAGCATATAAACAAAGCCAGTCCATTATTGTTAGTGGTGAGAGTGGAGCTGGTAAGACTGAGTCTACAAAATACATCTTGagATACCTGACAGAATCCTGGGGATCTGGTGACCAGGGACGCATTGAGCAAAGAATTATAGAAGCCAATCCCCTTCTTGAATCATTTGGTAATGCAAAGACACTAAGGAACATCAACAGTAGTCGCTTTGGCAAATATGTTGAAGTCCATTTTAATGAAAAGGTGATTGTCGTGGGAGGATTCATTTCTCACTACCTTCTGGAGAAGTCTCGTATCTGTAAGCAGTCCAAAGGTGAACGCAACTACCATGTCTTCTACAGACTCTGTGCTGGGGCACCTAAAGATATCCGAGATAAGCTGCAACTTAAAAAAGCAGAAGACTTTGTGTACCTGAAGCAGGGCTCTATCAAAGACCCAAGTTTAGATGACGTCAAGGACTTCAAGCGAATGGACCAATCAATGGACAATGTTGGATTCTCAAAGGAGGAGAAGGATAACATCTACAGGGTGGTTGCAGCCGTACTTCATCTTGGGAACATTGAGTTTGAGGAGAAGGATGATGCCAAGGgtGGCTGTGTAGTGACTGCTAAATCCATGAATGATCTCAACACCACAGCTATTCTGCTCAGAGTATCCTCAGAAGAGCTACAGATGTCCCTGACAACCAGAGTGATGTCTGCAGGTGGAGCAGACATGAGGTCGGACAGCATACCACGCCCGCCAAAGCAACAAATATTGGTGCCATTGACCAAAGAACAGGTTGGAGCAGCAAGAGATGCCTTAGCTAAAGCGCTTTACACCAAGCTGTTTGATCACATAGTCGCACAGGTCAACCAGTGCTTTCCTTTCAGCTCTTCATCCACTTATATTGGTGTGCTGGACATCGCTGGTTTTGAATACTATGAACTGAACAGCTTTGAACAGTTCTGCATCAACTACTGTAACGAAAAGCTACAGCAGTTTTTCAATGACAGGATTCTCAAACAGGAACAAGAGCTTTACAACCGTGAGGGACTGGGCGTAAAGGCTGTGAAATACATGGACAACCAGGATTGTATTGATTTGatagaagagaaaagaattgGTATCTTTGACATCCTGGATGAAGAAAGCAAGCTGCCTAAACCAACATCGGCTCATTTCACGACAGAGATTCACCTGAAACATAAGAACCACTTTAGATTGACGTTACCCAGGAAGTCACCTCTGATGTATCATCGTAACCTACGCGATGACGAAGGATTCCTGATTCGTCACTTTGCTGGAGCCGTGTGTTATCACACATCACAATTCCCTGACAAGAATAACGATGCCCTTCACCATGATCTAAAAGAACTGATCAGCGACAGCGAGGATGCCTTCATCAAGAGTCTTTTCCCCGGTGAGGCCAGCGATGACAAAGTCATGGGTAACCTGAGCATAgcaggaggaggaggaaggcAGGGAAGCAAGAAGCTTGCCTTTGTCAGCGTTGGCAGCAAGTTTAGGACTCAACTTAGCCAGTTGATGAACAAGCTGAATTGTACTGGCGCTAATTTCATTCGCTGCATCAAACCAAACGGCAAGATGACCAGTAGTCTGTTTGAAGGTGGTTCCATTCTAAGCCAGTTAGAATGTGCTGGTATGGTATCAGTACTAACACTCATGCAGGATGGATGGCCTTCCAGGGCACCCTTCCACGAGGTCTACGCAATGTACAAGAAGTTCCTACCGGCAAGACTAGTACGTCTTGATCCGCGCATGTTCTGCAAGGCTCTGTTCCATGCTGTTGGTATGAATGAGAATGATTTCAAGTTTGGTTCGTCCAAAATCTTTTTCAGACCAGGAAAGtttgCAGAGTTCGATCAGATCATGCAACAAGACCCGGAGAGTCTAAAGAAGATGGTTGCCAAGGTAACCACCTGGCTGACCCGCGCGCGCTGGAGGCGAGCTATCTGGGGGACCCTTTGCGTCATTAAACTTGCGAACAAGATCAAGTTCCGTGCTCTTGCCATAATTAGGATCCAGAAGACAATAAGGATGTCTAATGCTATTATTAAACATCGACCAAGGTACAAGAACATTATGAAGATTCGAAGACTCGAGGTACAAGTTGGCACAATGGCAGAACTTGCATCCAGCCTGAAGAAAGACAAAGACGTTGTGGTCAAACAAGTCAAGGATGTTAGCAACTCCATCAACGCAGCAATCGTCAAGATTAAGTCTACCATCATGACGCGCCAAGCCATGGAACAAGAATACAACAGTCTGGTACAGAAAGTGAACAACCAACTGAACGACTTGAAtaaacgacaacaacaacagaaggTCGCTGAGGAGCAAGAAAGACTCAGGAAGATACAAGAACAAATGGAgttggaaagaaagaagagggaagaagaagagagaaagagaaaagaagaagaggaagaaaggaagagGAAAATTGCGATGGAAATCGCGAGgaagaaggaagaagaagagcGTAAAAAAcgcgaagaagaagaaagaatacaaagagagaaagaggaaaaagacaGACAATTGCAGCTTGAGAAGCAGAAGTTACTAGAAGAAGAGCAAAAACGGCAAGAGATGATTGAACAAGAAAGACGTGATCGTGAACTGGCTTTAAGACTGGCCAATGTAAGTGAAAATGGTGTGAATAATAGTCATTTAAGCACACATTTAATTACAACTATCGCGAATTTACCAGCTAAAAAAGACAAGAAGCACGATTTAACTTCTTGGAAATATGCAGATCTACGAGATACTATCAATACGTCTTGTGATATCGAGTTGCTTGAGGCATGTAGACAGGAATTTCATCGTCGTCTCAAAGTTTATCATCAGTGGAAGAAAACGAACAAAGCTCGTGTCACGCCAGAGGAAGGCGCACCTCAGAGAGCGCCAAAAGATATCCAAGAAAAAGCTGAGCAAAATAAACCACCCCTCCCTCCTCGTCCAGCTCAAGCCAACGAACCTCCCCCATCCCTTCCCCCTCGTCGTTTGCAACGATTCTTCCGTGTTCCATTTAGTAAACGATCGGATAAATACCGTGATACTGTGTACAAGAAACAAGGATCGTGgTTTGCTCATTTTGATGGTCAGTGGATTGCCCGTCAGATGGAGCTCCACCAGGGTAAGAAGCCCCTGTTACTAGTAGCTGGTGATGACGATCTAGACATGTGTGAACTGAGTCTAGACGAGACTGGCCTAACCAGGAGGACTGGTGCTGAGATAACTAGACAAGAATTTGAAAACTTGTGGATTCAGTATGGTGGCGGTCAGCTAGTCTATCAAGCTAAAATCTACCAAGGGCAGTAA

Transcript

ENSQPTT00000022481

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9I8D1	Unconventional myosin-VI OS=Gallus gallus OX=9031 GN=MYO6 PE=1 SV=1
Q64331	Unconventional myosin-VI OS=Mus musculus OX=10090 GN=Myo6 PE=1 SV=2
E1BPK6	Unconventional myosin-VI OS=Bos taurus OX=9913 GN=MYO6 PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003877 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21521 all species →	MYO6_lever	Myosin VI, lever arm	Domain	Interproscan
PF16521 all species →	Myosin-VI_CBD	Myosin VI cargo binding domain	Domain	Interproscan
PF02736 all species →	Myosin_N	Myosin N-terminal SH3-like domain	Domain	Interproscan
PF00063 all species →	Myosin_head	Myosin head (motor domain)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008989 all species →	Homologous_superfamily	Myosin S1 fragment, N-terminal	Interproscan
IPR001609 all species →	Domain	Myosin head, motor domain	Interproscan
IPR049016 all species →	Domain	Myosin VI, lever arm	Interproscan
IPR032412 all species →	Domain	Myosin VI, cargo binding domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR004009 all species →	Domain	Myosin, N-terminal, SH3-like	Interproscan
IPR036114 all species →	Domain	Class VI myosin, motor domain	Interproscan
IPR036961 all species →	Homologous_superfamily	Kinesin motor domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13140 all species →	MYOSIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003774 all species →	Molecular Function	cytoskeletal motor activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0051015 all species →	Molecular Function	actin filament binding	Interproscan
GO:0016459 all species →	Cellular Component	myosin complex	Interproscan
GO:0000146 all species →	Molecular Function	microfilament motor activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006897 all species →	Biological Process	endocytosis	Interproscan
GO:0007015 all species →	Biological Process	actin filament organization	Interproscan
GO:0015629 all species →	Cellular Component	actin cytoskeleton	Interproscan
GO:0030050 all species →	Biological Process	vesicle transport along actin filament	Interproscan
GO:0030139 all species →	Cellular Component	endocytic vesicle	Interproscan
GO:0031982 all species →	Cellular Component	vesicle	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10358	MYO6; myosin VI	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →