Genomic Location: chr19:1893390...1896827
NR annotation: XP_031574242.1, serine/threonine-protein kinase/endoribonuclease IRE1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
| CDS |
| ENSQPTT00000023142 |
| Transcript |
| ENSQPTT00000023142 |
| Protein |
| ENSQPTP00000018831.1 |
| UniProt accession | Description |
|---|---|
| Q54IE8 | Probable serine/threonine-protein kinase irlE OS=Dictyostelium discoideum OX=44689 GN=irlE PE=3 SV=1 |
| O94537 | Sensor for unfolded proteins in the ER ire1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ire1 PE=1 SV=1 |
| Q55GJ2 | Probable serine/threonine-protein kinase ireA OS=Dictyostelium discoideum OX=44689 GN=ireA PE=3 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000794 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00069 all species → | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR008271 all species → | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR045133 all species → | Family | Serine/threonine-protein kinase/endoribonuclease IRE1/2-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13954 all species → | IRE1-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0004521 all species → | Molecular Function | RNA endonuclease activity | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0030968 all species → | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0036498 all species → | Biological Process | IRE1-mediated unfolded protein response | Interproscan |
| GO:0051082 all species → | Molecular Function | unfolded protein binding | Interproscan |
| GO:0070059 all species → | Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | Interproscan |
| GO:1990604 all species → | Cellular Component | IRE1-TRAF2-ASK1 complex | Interproscan |
ENSQPTP00000018831.1.Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
