Gene detail

Detailed information of ENSQPTP00000021918.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031565141.1, NEDD8-activating enzyme E1 catalytic subunit-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8TBC4	NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2
Q5R4A0	NEDD8-activating enzyme E1 catalytic subunit OS=Pongo abelii OX=9601 GN=UBA3 PE=2 SV=2
Q8C878	NEDD8-activating enzyme E1 catalytic subunit OS=Mus musculus OX=10090 GN=Uba3 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004430 (this species only)
Ubiquitin family	E1\|ThiF\|ThiF · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00899 all species →	ThiF	ThiF family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045886 all species →	Family	ThiF/MoeB/HesA family	Interproscan
IPR035985 all species →	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR033127 all species →	Active_site	Ubiquitin-activating enzyme E1, Cys active site	Interproscan
IPR030468 all species →	Domain	NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain	Interproscan
IPR023318 all species →	Homologous_superfamily	Ubiquitin activating enzyme, alpha domain superfamily	Interproscan
IPR000594 all species →	Domain	THIF-type NAD/FAD binding fold	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953 all species →	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0019781 all species →	Molecular Function	NEDD8 activating enzyme activity	Interproscan
GO:0032446 all species →	Biological Process	protein modification by small protein conjugation	Interproscan
GO:0045116 all species →	Biological Process	protein neddylation	Interproscan
GO:0008641 all species →	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10686	UBA3, UBE1C; NEDD8-activating enzyme E1	EC:6.2.1.64	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.