Gene detail

Detailed information of ENSQPTP00000022314.1 in Actinia mediterranea

Genomic Location: chr2:7209835...7236887
NR annotation: XP_031562034.1, solute carrier family 12 member 6-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQPTT00000027387

ATGTCTCAGGTTCGTTTTAAGGTTTCTAAGCTGGATGAAGACGCGGCTAGTGAAGTAACTTCGGATGCAGAAACCAAGACGTCAGCAAACCAAGAAGTGGACGAAGACCCCTCATTCGTGAAAATAGAAATTGAAGATCCAGCAACGTCTGCCAAAAACACAAGTGTGCGTCAAAATCTCCTTGCGACCAAAGATGGCAACTTGGCTTTGTATGAGGATGAAATCCACCGAAGACCAAAAATTTCTTCACTTTTGTCATCCTTGGCGAAGTATGAGGCTTCTGTACCTGCACAAGAAGAAGATGCAGAACCAAAGAAAAAGgaGGCCAAGATGGGTACCCTTATGGGGGTATACTTGCCTACCGTTCAGAATATCTTGGGTGTCATCCTGTTCATTCGTTTGTCTTGGTTGGTGGGAGTAGCTGGTGTTGTTCAAGGATTTTTCATTGTGCTAACTTCATGCTGTTGTACTATGTTAACAGCTATCTCAATGAGTGCTGTAGCTACTAATGGAGTCGTTCCAGGTGGAGGTTCATACTTTATGATTTCAAGAGCCCTTGGTCCAGAATTTGGTGGTGCAGTTGGACTGCTGTTCTATTTAGGAACGACATTTGCATCATCTATGTATATTCTTGGTGCAATTGAAATATTGCTGACCTACATTGCCCCAGTTATGTCTCTGTTTGGTGATGCTAACTCTGGAGGTGGTGCAAGCTCTTCTCTCATGTTGAATAACATGCGTGTGTATGGTACCATCTTGCTAGTCCTGATGGGGCTTGTGGTGTTCATTGGTGTTAAATATGTCAACAAGTGTGCCTCGATGTTCCTAGCATGTGTCATACTATCAATATTGGCTATATATGTTGGGTTTTTCTCTGCACATGCAAGGGACCTACCAAAGATTTGTATTCTTGGTAAGACAGTGCTATCCACAACTAGCTATGATACATGTTCGCGTAATGACTCTAAGTTGATAGCAGCGTATGGTTCAAACAGTGAATTCTGGAACTCCACCTCTTTGAAATACATTGATGGTGTTCCTGGTATTACTGGTGGTGTGTTTGCAGGAAATGCAAGAAGCTTTTATGTGAAGAAGAATGAAGTTTATCCTGGAGTTAAAGCTGGGTCATATCAGGGAGAAGTCAGATCAGATATCAGTACATCTTTCTTTATATTACTGGCTATCTTCTTCCCATCTGTTACTGGAATAATGGCAGGATCAAACAGGTCTGGTGATCTCAAAGATGCACAGAACTCAATACCCAAGGGAACTATTGCTGCCATAGCAACAACATCCTTCATTTACTTGACATGTGTTTTACTATTTGGTGCCACCATAGAAGGTGCTCTTCTAAGAGACAAGTTTGGTCGCAGTATTGGTAGTGTAATGGTAGTCGCTAATATAGCCTGGCCAACCAAATGGGTCATTTTGATTGGCTCATTCTTGTCGACAGTTGGTGCTGGTATGCAGAGCCTGACAGGTGCACCTCGTCTTCTACAAGCAATAGCCCGTGACAACATCATCCCCTTCTTGAACATATTCTCTGTGGCTTCCAAGTCTGGTGAACCAACTAGAGCTTTACTATTGACTATTTGTATATCAGAGATTGGTATCCTGATTGCTAACCTGGACAGTGTGGCTCCTATTATTACCATGTTTTTCCTGATGTGCTATGCATTCGTTAACTTAGCATGTGTGGTGCAGTCTTTACTGAAAACCCCCAACTGGCGGCCACGATTCAAGTATTATCATTGGTTTACGTCATTCCTTGGAGTTTGCTTATGTGTAGCCCTGATGTTCATATCCAGTTGGTACTACGCATTAGTGGCAATGATAATTGCCGCTGCCGTCTATAAATACATTGAGTTTCAAGGTGCCAAGAAGGAGTGGGGTGATGGTATCCGAGGTCTGAACCTGAGTGCTGCTCGTTACAGCTTGATGAGGCTCGAAGAAGGCCCCACACATACCAAGAACTGGAGGCCTGAGATACTGATTTTATGTAAGCTGAACGAAGGCTATCAGCCTCAAAGTCCACGTCTTCTCAGCCTTGCCAGTCAGCTCAAAAAGGGTAGAGGACTGTCAGTAGTTGGTTCTGTCTTGGAGGGATCCTTTACTTACGAACAGAGAGCAAAAGATGTTCAATCTGCTAAAGAGATTTTACGTCAGAACATGAACGATGAGAAAGTCAAAGGATTCATGAAGGTGATAACTGCCGAAGACGTCAAGGAAGGAATATCCTATCTGATACAGGCTAGTGGGTTAGGTGCTTTGGAGCCAAACACAGTACTCTTAGCCTGGCCTGAGAATTGGAGAGAAAGAGACCAATGGAAATCCTTTGTTCAAACGGTCAATACCGTAGCACTTGGAGAATCAGCTCTACTAGTTCCCCGTAAGATCGACCTGTTCCCAGATAACCATGCCAGACTGGAAGGCCACATGGACGTGTGGTGGATCGTGCATGATGGTGGCATGATGATACTCATTCTATTCCTACTCAGACAGCATAAGGTCTGGAGGAAATGTAAACTAAGGATCTTCACCGTGGCGCAGCTTGAAGACAACAGTATCCAGATGAAGACTGATCTCGAGACCTTTATGTACCACCTAAGGATCAAAGCCACTGTAGAGGTCATTGAAATGGTTGATCAAGATATCTCTGCTTACACCTACGAGCGAACCCTCAAGATGGAACAAAGAACACAAATGCTCAAGGAAATGAAGCTGACCAGGAAAGAAAGCAAACGCGAGGTTCAGAATTTGGTCGTCAACTCTTTCCGACCTCGTTCTACCTCATACAGCAAAGCTACACGCTCAGCAAGTGTTAATGAGGGGCCTCGAAGCAGAAACGAATCTAGTGTTACTCAAAGGGATTATGCAGTAGAGGGCTTAACCCGCCGTCCGTCAAGGGAGGACGAAGAGGTTGaagctgatgatgatgataatgaagaagaagattCAGAACCCCAAGAGAGGAATCTGCGTCGCATGAATACCGCAGTCAAGCTGAATCAGATCATCAGGGAGAAGTCTGGTGGGTCTCAGCTGCTGGTCGTCAATCTACCAGCCCCCCCTGACAACAAGGAAGAGTGGGAAAACTaTATGGAATTTTTGGATGTCCTCACAGAAGGACTGGATCGAGTATTAATGGTTAGGGGTGGAGGGTACGAGGTTGTGACCATATACTCCTAA

Transcript

ENSQPTT00000027387

TAGTTTTCCAGTTTTCCTGTCAGTGTAGTAAAACAGGTCAAGGAGGAACCTGCGGTACTTCTCTTTTTCTTCGGGCTGAAAGAAAACTAATTCGAACTGGGCTTCACATCATGTCTCAGGTTCGTTTTAAGGTTTCTAAGCTGGATGAAGACGCGGCTAGTGAAGTAACTTCGGATGCAGAAACCAAGACGTCAGCAAACCAAGAAGTGGACGAAGACCCCTCATTCGTGAAAATAGAAATTGAAGATCCAGCAACGTCTGCCAAAAACACAAGTGTGCGTCAAAATCTCCTTGCGACCAAAGATGGCAACTTGGCTTTGTATGAGGATGAAATCCACCGAAGACCAAAAATTTCTTCACTTTTGTCATCCTTGGCGAAGTATGAGGCTTCTGTACCTGCACAAGAAGAAGATGCAGAACCAAAGAAAAAGgaGGCCAAGATGGGTACCCTTATGGGGGTATACTTGCCTACCGTTCAGAATATCTTGGGTGTCATCCTGTTCATTCGTTTGTCTTGGTTGGTGGGAGTAGCTGGTGTTGTTCAAGGATTTTTCATTGTGCTAACTTCATGCTGTTGTACTATGTTAACAGCTATCTCAATGAGTGCTGTAGCTACTAATGGAGTCGTTCCAGGTGGAGGTTCATACTTTATGATTTCAAGAGCCCTTGGTCCAGAATTTGGTGGTGCAGTTGGACTGCTGTTCTATTTAGGAACGACATTTGCATCATCTATGTATATTCTTGGTGCAATTGAAATATTGCTGACCTACATTGCCCCAGTTATGTCTCTGTTTGGTGATGCTAACTCTGGAGGTGGTGCAAGCTCTTCTCTCATGTTGAATAACATGCGTGTGTATGGTACCATCTTGCTAGTCCTGATGGGGCTTGTGGTGTTCATTGGTGTTAAATATGTCAACAAGTGTGCCTCGATGTTCCTAGCATGTGTCATACTATCAATATTGGCTATATATGTTGGGTTTTTCTCTGCACATGCAAGGGACCTACCAAAGATTTGTATTCTTGGTAAGACAGTGCTATCCACAACTAGCTATGATACATGTTCGCGTAATGACTCTAAGTTGATAGCAGCGTATGGTTCAAACAGTGAATTCTGGAACTCCACCTCTTTGAAATACATTGATGGTGTTCCTGGTATTACTGGTGGTGTGTTTGCAGGAAATGCAAGAAGCTTTTATGTGAAGAAGAATGAAGTTTATCCTGGAGTTAAAGCTGGGTCATATCAGGGAGAAGTCAGATCAGATATCAGTACATCTTTCTTTATATTACTGGCTATCTTCTTCCCATCTGTTACTGGAATAATGGCAGGATCAAACAGGTCTGGTGATCTCAAAGATGCACAGAACTCAATACCCAAGGGAACTATTGCTGCCATAGCAACAACATCCTTCATTTACTTGACATGTGTTTTACTATTTGGTGCCACCATAGAAGGTGCTCTTCTAAGAGACAAGTTTGGTCGCAGTATTGGTAGTGTAATGGTAGTCGCTAATATAGCCTGGCCAACCAAATGGGTCATTTTGATTGGCTCATTCTTGTCGACAGTTGGTGCTGGTATGCAGAGCCTGACAGGTGCACCTCGTCTTCTACAAGCAATAGCCCGTGACAACATCATCCCCTTCTTGAACATATTCTCTGTGGCTTCCAAGTCTGGTGAACCAACTAGAGCTTTACTATTGACTATTTGTATATCAGAGATTGGTATCCTGATTGCTAACCTGGACAGTGTGGCTCCTATTATTACCATGTTTTTCCTGATGTGCTATGCATTCGTTAACTTAGCATGTGTGGTGCAGTCTTTACTGAAAACCCCCAACTGGCGGCCACGATTCAAGTATTATCATTGGTTTACGTCATTCCTTGGAGTTTGCTTATGTGTAGCCCTGATGTTCATATCCAGTTGGTACTACGCATTAGTGGCAATGATAATTGCCGCTGCCGTCTATAAATACATTGAGTTTCAAGGTGCCAAGAAGGAGTGGGGTGATGGTATCCGAGGTCTGAACCTGAGTGCTGCTCGTTACAGCTTGATGAGGCTCGAAGAAGGCCCCACACATACCAAGAACTGGAGGCCTGAGATACTGATTTTATGTAAGCTGAACGAAGGCTATCAGCCTCAAAGTCCACGTCTTCTCAGCCTTGCCAGTCAGCTCAAAAAGGGTAGAGGACTGTCAGTAGTTGGTTCTGTCTTGGAGGGATCCTTTACTTACGAACAGAGAGCAAAAGATGTTCAATCTGCTAAAGAGATTTTACGTCAGAACATGAACGATGAGAAAGTCAAAGGATTCATGAAGGTGATAACTGCCGAAGACGTCAAGGAAGGAATATCCTATCTGATACAGGCTAGTGGGTTAGGTGCTTTGGAGCCAAACACAGTACTCTTAGCCTGGCCTGAGAATTGGAGAGAAAGAGACCAATGGAAATCCTTTGTTCAAACGGTCAATACCGTAGCACTTGGAGAATCAGCTCTACTAGTTCCCCGTAAGATCGACCTGTTCCCAGATAACCATGCCAGACTGGAAGGCCACATGGACGTGTGGTGGATCGTGCATGATGGTGGCATGATGATACTCATTCTATTCCTACTCAGACAGCATAAGGTCTGGAGGAAATGTAAACTAAGGATCTTCACCGTGGCGCAGCTTGAAGACAACAGTATCCAGATGAAGACTGATCTCGAGACCTTTATGTACCACCTAAGGATCAAAGCCACTGTAGAGGTCATTGAAATGGTTGATCAAGATATCTCTGCTTACACCTACGAGCGAACCCTCAAGATGGAACAAAGAACACAAATGCTCAAGGAAATGAAGCTGACCAGGAAAGAAAGCAAACGCGAGGTTCAGAATTTGGTCGTCAACTCTTTCCGACCTCGTTCTACCTCATACAGCAAAGCTACACGCTCAGCAAGTGTTAATGAGGGGCCTCGAAGCAGAAACGAATCTAGTGTTACTCAAAGGGATTATGCAGTAGAGGGCTTAACCCGCCGTCCGTCAAGGGAGGACGAAGAGGTTGaagctgatgatgatgataatgaagaagaagattCAGAACCCCAAGAGAGGAATCTGCGTCGCATGAATACCGCAGTCAAGCTGAATCAGATCATCAGGGAGAAGTCTGGTGGGTCTCAGCTGCTGGTCGTCAATCTACCAGCCCCCCCTGACAACAAGGAAGAGTGGGAAAACTaTATGGAATTTTTGGATGTCCTCACAGAAGGACTGGATCGAGTATTAATGGTTAGGGGTGGAGGGTACGAGGTTGTGACCATATACTCCTAATGTTATCGAAATCAGAGCTAATGGCAAGGGACTGACGTCATGTGGGTGGAGCCATGCTATTTTTACCATATTCATAATAGCAAATGCCTTCAAACagtttctttactttttattgTATTGACCCAAATGCCTCGACTTATGACAATTGTTTGAAAGCAATATCTGCTATTACGTGACCCAGACAGAGTTATCATTCAAGTCGTCTGGGTTTTTGACTGGTCCAGGAATTTGTGTTGCACGAGTTTGCGCAAAACTTTTTTCGTAGGTGaagtgcttgctcgatattttttgGGGATTTACggaccccccacccccctccacctcaattatctaatggtccgtcccttaCAGCTTGTTGTCTCGGTCGCGTAATTATGAAAATGGTAGTAAACAAGGATAATGCCGTGAGAGGTGTGTCGTGATACAATCAGTATCAGTAAGAGCTAATGATCAAGGATGGGGCTTTGGGTAAACAAGGGTATTTAATTGACCGCTTTTGTATGCTAACTCAGTGGTTACAACACAAACCATTCATCACTAGtcccctgcgccatcttgaaaggtaaccgtgccTTGGCATCGCGACGAGGCGAACggcgagcttgcaatgatagagacctttttaaacaccttggacaaCTATTAATAGCATTCTGAAgcagattttattttattttttcatggcatttattttattttattgaatctAACTTTTTAAATCTAATTTTATTGCATTGGAATTATAAGACTCCACATTATAAGAGTTATTTAGCGAAATTAAATGTGGTTGTCGGGAAAGGAAATTACCCACCCTTTATTAGTTCATAGTGTGAATATATTGcggaaattcttttttttgtttgtttgttttttgtttgctttttggCTTCAAGCTTGGTGATTGGATAGGGagcattttttctcttttgacACATTCAGATCGAAGAAAACCATTTTACAGTCACATTTTCTGTCTTTGAATTTGTTCAGACCATTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9Y666	Solute carrier family 12 member 7 OS=Homo sapiens OX=9606 GN=SLC12A7 PE=1 SV=3
Q924N4	Solute carrier family 12 member 6 OS=Mus musculus OX=10090 GN=Slc12a6 PE=1 SV=2
Q9UHW9	Solute carrier family 12 member 6 OS=Homo sapiens OX=9606 GN=SLC12A6 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005002 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03522 all species →	SLC12	Solute carrier family 12	Family	Interproscan
PF00324 all species →	AA_permease	Amino acid permease	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000076 all species →	Family	K/Cl co-transporter	Interproscan
IPR018491 all species →	Domain	SLC12A transporter, C-terminal	Interproscan
IPR004841 all species →	Domain	Amino acid permease/ SLC12A domain	Interproscan
IPR004842 all species →	Family	SLC12A transporter family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11827 all species →	SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006811 all species →	Biological Process	monoatomic ion transport	Interproscan
GO:0015379 all species →	Molecular Function	potassium:chloride symporter activity	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0022857 all species →	Molecular Function	transmembrane transporter activity	Interproscan
GO:0055085 all species →	Biological Process	transmembrane transport	Interproscan
GO:0015377 all species →	Molecular Function	chloride:monoatomic cation symporter activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006884 all species →	Biological Process	cell volume homeostasis	Interproscan
GO:0007268 all species →	Biological Process	chemical synaptic transmission	Interproscan
GO:0055064 all species →	Biological Process	chloride ion homeostasis	Interproscan
GO:0055075 all species →	Biological Process	potassium ion homeostasis	Interproscan
GO:1902476 all species →	Biological Process	chloride transmembrane transport	Interproscan
GO:1990573 all species →	Biological Process	potassium ion import across plasma membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K14427	SLC12A4_6, KCC1_3; solute carrier family 12 (potassium/chloride transporter), member 4/6	-	Transporters	ko02000	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →