Gene detail

Detailed information of ENSQPTP00000024575.1 in Actinia mediterranea

Genomic Location: chr4:2503237...2531598
NR annotation: XP_031554686.1, FERM, ARHGEF and pleckstrin domain-containing protein 1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQPTT00000030052

ATGGCCCGGCGTTCGTACGAAGTGAACGAGGAAGGGAGTGGTGGTCAGAGAAGAGGTCGACGGAAAGCCGCTATAAAAGTGTGTATGCTCGACGACTCCGTGGTTAAATTCGACGTTGAGTCTAAAGAAAAAGGAGATGTATTATACAAACAAGTGTACGAATACTTAAACCTGGAGGAATGTGAATATTTTGGGCTTCATTACTATGACAAAACTGATAATCTGTTCTGGCTGGACCAGCAGAAGCCAATCAACAAACAAATACATGACACGAGCAAGGTTCTGCTGAGATTTAGTGTCAAATTCTATGCTCCAGACCCTTCAATGTTACAAGAGGAGTATACAAGATACATGTTTGCTCTTCAAGTAAAAAGAGATCTCTTAAGTGGAAGATTAAAGTGTTCAGAGAGTACAGCTGCATTATTAGCATCATATATCGTTCAAGGGGAACTTGGAGACTTTGACTCGCTGACTTGTCGTCCAGGATATCTTGCTGAATTTCAGTTTTTTCCAGAACAGAATATAGACTCAGAAGCAAAAATTGCAGAGTTCCACAAACAGCACAAGGGATTTAGTCCATCAGATTGTGATTATAATCTTCTGGATGTGGCTCGGCGACTAGAAATGTACGGTATAATACTCTATCCAGCAAGGgATAAAGATAACGTAGAACTTGATCTTGCAGCTGCAAACATGGGCATACTTGTGTTCCAGTCTGGCGCAAAAATCAATACCCTATCATGGGCAAAAATCAGAAAGCTAAgcttcaaaagaaaaagattccTCATTAAACTCCATCCTGAAATATtcGGTCATTATAAAGATGTGGTAGAGTTCCAGATGGGTAGTAGAGACGCATGCAAAAGCTTCTGGAAAGTTGCCATTTCAACACATGCATTTTTCAgACAATCACAGAGTCAAAGTCCACCAAAACACAGACCCAAAGTGTTCAGTAGAGGGTCCTCCTACAGATTTAGTGGTCGAACACAAAAACAGATCATTGAATCTACCATGGAAAACTCCAGACAGCAACTAGCTTTTAACAGAACCCAGAGCTTAAAAACCCCAAACAGAAACAACACACCTCGCACAAGCCAATCTACAGCCAAACCTTATGGAGGATTTGGTGATGCCGAAACAAGAGTAGTGGAATCTGCCCCAGTACGACCAGATGAAGATCAACATACAACAGATACACCAGAACTGCAAATAGAGGGTCTGCCACTGGAAAATGGAATGGATGCAATGGAAGAGGAATCTGATCATGAAGAACTACATGAACCTGGGTCGGTAATCAAGGTACAGTCAGCTGAAAACCCTGATGAGGATATCCCATTAAAAGACCTTGATCATGAACCAGACATGATGAGAGATGAGTCATCAGTGTCATCCGTGTCGCAACAAGACTTGGAATGGCAGGAAGAAGTCATAAGTGAGCTTCCTCCTCagaatgaaattcaatatatGGCCCCTAATGAAGATAGGAACAGGGACATTATACTGCCACCAGGTGCCATCGAAATTGAGTGCAAACCACAACCAAGACCACCGACTCCTATTGAAGTTGATGGAGTGGAATCACCTCCCCCACCCTTCCCCAATGAGGAAGtggaagacgaagaaattgcaTCCAAAGAATTTAGGCCAGTAGAATTAGCGCgtgatgaacaggaagaattTCCTGCGCCTCCCATGGAAACATTGCCGTCACCGCCACCAGAACTCCTTCGTGATAGCCCCGATCCTGACAGGATAGATGAGGAACCCTACAACATGCCTGTTGTGCAAACAAATGGTTACCATGAACAGAAAAGCCACGAGCCTCTCCAGATAACATGCACAAGTGTAGTCAAAGTACAAAATGGAGAAGTGTCACGGCATGGAAAAGGGAGTTCAGGTTCCCGTCATAGCACAGATGATGATGCAGAGCAGCAGGATGGGCATGACAATGTTTTTGAAGAACAAGTGTCACCAATGTTCCGTAGTGATACTGAGGCTTCACCTCCAGCTTCGCCAATTCTGGTGACAGCATTGAAATCAGAACAGACCTTATCTAAGTCAGGTTCTGGAGCAGCTTATACCATCGCAAAAGAGCTTCTGAACACAGAAAGAACTTATGTAAAGGACTTGGAAGTAATAACCATCTCATTCAGAGAAGTCGTCAGTCCTCCAGGAGTTCTTCCAGATTCTTCCAAGAACCTGCTATTTTCAACCATTGATCCTATCTATGATTTCCATTGCACTTTCCTGGCTGAATTAGAAGAAAGAATGGCTTTATGGGATGAAAGAATTGCAGAGAATGCCAAGCCACCAATATTTGGAGACCTGATGCTTAGCAATATGAAACAGATAAAACGATATGTTGCACACCTTAAACGACATGATCAGGTGATGCTTAACTTGGAAACTGCTACCAAAAAGAACAAACAGTTTGATACCATCTACAAGGAATTTGAGACTCAAAAGGTGTGCTATCTCCCTCTGAATGCATTCCTCGTCAAACCATCTCAGAGACTTCTTCACTACAAATTTCTGCTTGAAAGACTATTAAAGTTTTGTCCAAGTACTAACCTAGATTATAAAGACTTGCAAGcTGCCTTAGTAGAACTGGGAAATGCAGTCAGAGAAACAGATGAAACCATGAAAAAACTGgaaaatgttcaaaaactgATAGAGCTACAGAGGGACTTGATAGGTGTCGAAGGTCTTGTGCAGCAAGGAAGGgACTTTATCAGGGAAGGTTGTCTGCAGAGAATAGCCAGGAAAGGACCACAGCCTAGGATGTTTTTCCTGTTTTCAGATCTTCTACTGTACACTTGTAAAGGAGTTACTGTGACAAATCAGTTCAGGGTTCAAGGACAGATTCCTCTTCACACTGTTAAGGTTGAGGATGTTGGCCCAGATCTGCATGGACTGTACCCATTTACCATAACCTACTCTAACAAACACATGGTGGTCGCTGCTCAGtcggaagaagaaaaatacaagTGGTTAGAGGATCTTAATTCTGTCGTCAGGCATGCAAAAGAAATGGCTACCTGCAGTCAGTGTATGTATAACAGAGCACACCACATGTTCAAATCACCAGATGGAAGGAACACTAAGTACTTCTGTGAGGAATGCTATATCCTGGTCGATGAAGATGAACCTATCATGGATGTCCTAAGTGGACAGACTGGTACTTATCTTGAACATAATAAAAACCTTTACAATGGAGATAACCAAAATGGCGATAATCGATATAAAATACttcccctccccacccctgtAACAATACATCGAAGCAGCTCTGGTGATGATGGCTCAGATGATGAGGCTACATCCACAAGTCCTGTGTCGAGTCTGGATAGACGACATGCTCACTCCAATACCATGTCTACCCGTCGTGTGTGTTGGCACAGGAATACTAGTATTAGTATGAGTGAACATGCTCTCTCTGTACGGAATCACATGAGCGGGGATCTTCTTCGCAAGTTCAAGACCGGGAATCGTTGGCAGAAATTGTGGGTTGTTTTTACCAATTTCTGTCTGTTTTTCTACAAGACACACCAGgacGATTTTCCTCTAGCGAGTCTGCCTCTCATTGGGTATTTAGTCGACCTTCCTGCACCAGCCGACCAGATAGACAAGGGCTTGGTCTTCAAACTTCAATATAAGAGTCACGTGTACTTCTTCAGAGCGGACAACGAATACTCATTCCACAGATGGATGGAAGTGATCTCCAGCGCGACTCAGAGCTCGACAAGATCGCGAATCTTCAGCCGCATGGAGAGCAATGATCCTTAA

Transcript

ENSQPTT00000030052

AGTTAGTCGAAGCATCTGAGAGTAGTCTGTGTTCATGtcctttttacccaaaaaaacttgaaacttTCTCTGATTCGCACTTTCTTTTCGAGTTGTCTAGGGTTTAACAGCGCTTAAGCGCATGATTGGAGGCCTGGAGCATTTGTACTTGTACCGTATTTTAGTGTTTTAACGCTTTAATTGTGACAAGAAAAAGTACGAATTTTAGAAATGGCCCGGCGTTCGTACGAAGTGAACGAGGAAGGGAGTGGTGGTCAGAGAAGAGGTCGACGGAAAGCCGCTATAAAAGTGTGTATGCTCGACGACTCCGTGGTTAAATTCGACGTTGAGTCTAAAGAAAAAGGAGATGTATTATACAAACAAGTGTACGAATACTTAAACCTGGAGGAATGTGAATATTTTGGGCTTCATTACTATGACAAAACTGATAATCTGTTCTGGCTGGACCAGCAGAAGCCAATCAACAAACAAATACATGACACGAGCAAGGTTCTGCTGAGATTTAGTGTCAAATTCTATGCTCCAGACCCTTCAATGTTACAAGAGGAGTATACAAGATACATGTTTGCTCTTCAAGTAAAAAGAGATCTCTTAAGTGGAAGATTAAAGTGTTCAGAGAGTACAGCTGCATTATTAGCATCATATATCGTTCAAGGGGAACTTGGAGACTTTGACTCGCTGACTTGTCGTCCAGGATATCTTGCTGAATTTCAGTTTTTTCCAGAACAGAATATAGACTCAGAAGCAAAAATTGCAGAGTTCCACAAACAGCACAAGGGATTTAGTCCATCAGATTGTGATTATAATCTTCTGGATGTGGCTCGGCGACTAGAAATGTACGGTATAATACTCTATCCAGCAAGGgATAAAGATAACGTAGAACTTGATCTTGCAGCTGCAAACATGGGCATACTTGTGTTCCAGTCTGGCGCAAAAATCAATACCCTATCATGGGCAAAAATCAGAAAGCTAAgcttcaaaagaaaaagattccTCATTAAACTCCATCCTGAAATATtcGGTCATTATAAAGATGTGGTAGAGTTCCAGATGGGTAGTAGAGACGCATGCAAAAGCTTCTGGAAAGTTGCCATTTCAACACATGCATTTTTCAgACAATCACAGAGTCAAAGTCCACCAAAACACAGACCCAAAGTGTTCAGTAGAGGGTCCTCCTACAGATTTAGTGGTCGAACACAAAAACAGATCATTGAATCTACCATGGAAAACTCCAGACAGCAACTAGCTTTTAACAGAACCCAGAGCTTAAAAACCCCAAACAGAAACAACACACCTCGCACAAGCCAATCTACAGCCAAACCTTATGGAGGATTTGGTGATGCCGAAACAAGAGTAGTGGAATCTGCCCCAGTACGACCAGATGAAGATCAACATACAACAGATACACCAGAACTGCAAATAGAGGGTCTGCCACTGGAAAATGGAATGGATGCAATGGAAGAGGAATCTGATCATGAAGAACTACATGAACCTGGGTCGGTAATCAAGGTACAGTCAGCTGAAAACCCTGATGAGGATATCCCATTAAAAGACCTTGATCATGAACCAGACATGATGAGAGATGAGTCATCAGTGTCATCCGTGTCGCAACAAGACTTGGAATGGCAGGAAGAAGTCATAAGTGAGCTTCCTCCTCagaatgaaattcaatatatGGCCCCTAATGAAGATAGGAACAGGGACATTATACTGCCACCAGGTGCCATCGAAATTGAGTGCAAACCACAACCAAGACCACCGACTCCTATTGAAGTTGATGGAGTGGAATCACCTCCCCCACCCTTCCCCAATGAGGAAGtggaagacgaagaaattgcaTCCAAAGAATTTAGGCCAGTAGAATTAGCGCgtgatgaacaggaagaattTCCTGCGCCTCCCATGGAAACATTGCCGTCACCGCCACCAGAACTCCTTCGTGATAGCCCCGATCCTGACAGGATAGATGAGGAACCCTACAACATGCCTGTTGTGCAAACAAATGGTTACCATGAACAGAAAAGCCACGAGCCTCTCCAGATAACATGCACAAGTGTAGTCAAAGTACAAAATGGAGAAGTGTCACGGCATGGAAAAGGGAGTTCAGGTTCCCGTCATAGCACAGATGATGATGCAGAGCAGCAGGATGGGCATGACAATGTTTTTGAAGAACAAGTGTCACCAATGTTCCGTAGTGATACTGAGGCTTCACCTCCAGCTTCGCCAATTCTGGTGACAGCATTGAAATCAGAACAGACCTTATCTAAGTCAGGTTCTGGAGCAGCTTATACCATCGCAAAAGAGCTTCTGAACACAGAAAGAACTTATGTAAAGGACTTGGAAGTAATAACCATCTCATTCAGAGAAGTCGTCAGTCCTCCAGGAGTTCTTCCAGATTCTTCCAAGAACCTGCTATTTTCAACCATTGATCCTATCTATGATTTCCATTGCACTTTCCTGGCTGAATTAGAAGAAAGAATGGCTTTATGGGATGAAAGAATTGCAGAGAATGCCAAGCCACCAATATTTGGAGACCTGATGCTTAGCAATATGAAACAGATAAAACGATATGTTGCACACCTTAAACGACATGATCAGGTGATGCTTAACTTGGAAACTGCTACCAAAAAGAACAAACAGTTTGATACCATCTACAAGGAATTTGAGACTCAAAAGGTGTGCTATCTCCCTCTGAATGCATTCCTCGTCAAACCATCTCAGAGACTTCTTCACTACAAATTTCTGCTTGAAAGACTATTAAAGTTTTGTCCAAGTACTAACCTAGATTATAAAGACTTGCAAGcTGCCTTAGTAGAACTGGGAAATGCAGTCAGAGAAACAGATGAAACCATGAAAAAACTGgaaaatgttcaaaaactgATAGAGCTACAGAGGGACTTGATAGGTGTCGAAGGTCTTGTGCAGCAAGGAAGGgACTTTATCAGGGAAGGTTGTCTGCAGAGAATAGCCAGGAAAGGACCACAGCCTAGGATGTTTTTCCTGTTTTCAGATCTTCTACTGTACACTTGTAAAGGAGTTACTGTGACAAATCAGTTCAGGGTTCAAGGACAGATTCCTCTTCACACTGTTAAGGTTGAGGATGTTGGCCCAGATCTGCATGGACTGTACCCATTTACCATAACCTACTCTAACAAACACATGGTGGTCGCTGCTCAGtcggaagaagaaaaatacaagTGGTTAGAGGATCTTAATTCTGTCGTCAGGCATGCAAAAGAAATGGCTACCTGCAGTCAGTGTATGTATAACAGAGCACACCACATGTTCAAATCACCAGATGGAAGGAACACTAAGTACTTCTGTGAGGAATGCTATATCCTGGTCGATGAAGATGAACCTATCATGGATGTCCTAAGTGGACAGACTGGTACTTATCTTGAACATAATAAAAACCTTTACAATGGAGATAACCAAAATGGCGATAATCGATATAAAATACttcccctccccacccctgtAACAATACATCGAAGCAGCTCTGGTGATGATGGCTCAGATGATGAGGCTACATCCACAAGTCCTGTGTCGAGTCTGGATAGACGACATGCTCACTCCAATACCATGTCTACCCGTCGTGTGTGTTGGCACAGGAATACTAGTATTAGTATGAGTGAACATGCTCTCTCTGTACGGAATCACATGAGCGGGGATCTTCTTCGCAAGTTCAAGACCGGGAATCGTTGGCAGAAATTGTGGGTTGTTTTTACCAATTTCTGTCTGTTTTTCTACAAGACACACCAGgacGATTTTCCTCTAGCGAGTCTGCCTCTCATTGGGTATTTAGTCGACCTTCCTGCACCAGCCGACCAGATAGACAAGGGCTTGGTCTTCAAACTTCAATATAAGAGTCACGTGTACTTCTTCAGAGCGGACAACGAATACTCATTCCACAGATGGATGGAAGTGATCTCCAGCGCGACTCAGAGCTCGACAAGATCGCGAATCTTCAGCCGCATGGAGAGCAATGATCCTTAATTCGATGGAATTATTGTACATTGAGCAGCGAGAGCCGCTCCCTAAATTTTATAATCGCCTTGAATATTGCATAGTACTCCAAAATGTATAGAATTTTCTAAGTTTTCTGGTGGAATGCCTAGCGAATCTAGAGTAGTTATGCGAAGAAATAACGTATTTTTCCCTTTCAATATAATAGGGATCACAATTTGATTACTCGGGCCCCTTGTTTAGACAGCCCGAATGCATTGAAATGTTTTAGTGCTATTTATGCAAGGGAGCCCGAGTGAACGTCATTGTCGTAAGACCGATCTTGTTCAGGAAGCGCTTTGCGCGCACCGTTTAATGAATTTCCCATAATTGCAATAATCAATAAtgtatttgtaaaaaaaagtataaaatatAAGGGCTTCGTTTAGTCAATAACGTGGAAAAAAGATTTCGGAATTATGTAGAAGAAAACCAATCAAATGATgctatttcattttaaaaagaatttatGTCTTTATATAACACAGTACGTAATGGGGTAATATTACGCTAATAGGGACCAGCTTGCACCGCGATACAAATTCTGTTACTAGAACAGCTAAACATTATCGTTCCCAGATCTCGCCTTGGTCTCCGCCAAGAAGCGCGGAAGGGCCTGGTTGAACCCGAGAACCCAAACCATGAACAAGGTTTCCGGTTTCGATTTCATTGATTTGGCGCCTATTGGTTACTgtattagccaatcaggaaAAAGTGTCAGCTGTTTTCGCCCAAAGGCCTTTTTTTCTTGGTAGAGACAAAAATAGGCCTTTTCCAAATTGAATAAACTACTTCATTGTGGTCTAACTTGGATACAAACTTAAGTATGATGAATAAAAGTTGCCTTGTactcaagctagaccacaatgcaccatgatCGCTATCGCAGGAAAGGTCTATGAATGCGGGCTCTGTGAGAATGAGATTAATTTACCAGGGTCTGTACATGCAGTACATGTTTATGCCGTATTAAAACCAGAATTTCCAGAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q91VS8	FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Mus musculus OX=10090 GN=Farp2 PE=1 SV=2
O94887	FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3
F1P065	FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Gallus gallus OX=9031 GN=FARP1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001393 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00169 all species →	PH	PH domain	Domain	Interproscan
PF09379 all species →	FERM_N	FERM N-terminal domain	Domain	Interproscan
PF09380 all species →	FERM_C	FERM C-terminal PH-like domain	Domain	Interproscan
PF08736 all species →	FA	FERM adjacent (FA)	Family	Interproscan
PF00373 all species →	FERM_M	FERM central domain	Domain	Interproscan
PF00621 all species →	RhoGEF	RhoGEF domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR018980 all species →	Domain	FERM, C-terminal PH-like domain	Interproscan
IPR035963 all species →	Homologous_superfamily	FERM superfamily, second domain	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR000219 all species →	Domain	Dbl homology (DH) domain	Interproscan
IPR018979 all species →	Domain	FERM, N-terminal	Interproscan
IPR019749 all species →	Domain	Band 4.1 domain	Interproscan
IPR014847 all species →	Domain	FERM adjacent	Interproscan
IPR035899 all species →	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR000299 all species →	Domain	FERM domain	Interproscan
IPR051835 all species →	Family	RAC1-specific guanine nucleotide exchange factor	Interproscan
IPR000798 all species →	Family	Ezrin/radixin/moesin-like	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR019748 all species →	Domain	FERM central domain	Interproscan
IPR041788 all species →	Domain	FARP1/FARP2/FRMD7, FERM domain C-lobe	Interproscan
IPR019747 all species →	Conserved_site	FERM conserved site	Interproscan
IPR014352 all species →	Homologous_superfamily	FERM/acyl-CoA-binding protein superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45858 all species →	FERM DOMAIN CONTAINING PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0008092 all species →	Molecular Function	cytoskeletal protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06082	FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2	-	Adherens junction	ko04520	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →