Gene detail

Detailed information of ENSQPTP00000029621.1 in Actinia mediterranea

Genomic Location: :...
NR annotation: XP_031559736.1, DNA replication ATP-dependent helicase/nuclease DNA2-like [Actinia tenebrosa]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
D3ZG52	DNA replication ATP-dependent helicase/nuclease DNA2 OS=Rattus norvegicus OX=10116 GN=Dna2 PE=3 SV=1
Q8QHA5	DNA replication ATP-dependent helicase/nuclease DNA2 OS=Xenopus laevis OX=8355 GN=dna2 PE=1 SV=1
Q6ZQJ5	DNA replication ATP-dependent helicase/nuclease DNA2 OS=Mus musculus OX=10090 GN=Dna2 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13087	AAA_12	AAA domain	Domain	Interproscan
PF08696	Dna2	DNA replication factor Dna2	Family	Interproscan
PF21123	Dna2_Rift	Dna2 Rift barrel domain	Domain	Interproscan
PF13086	AAA_11	AAA domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR026851	Domain	DNA replication ATP-dependent helicase/nuclease Dna2/JHS1, DEXXQ-box helicase domain	Interproscan
IPR045055	Family	DNA2/NAM7-like helicase	Interproscan
IPR027417	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR041679	Domain	DNA2/NAM7 helicase-like, C-terminal	Interproscan
IPR014808	Domain	DNA replication factor Dna2, N-terminal	Interproscan
IPR048459	Domain	DNA2, rift barrel domain	Interproscan
IPR047187	Domain	Upf1-like, C-terminal helicase domain	Interproscan
IPR011604	Homologous_superfamily	PD-(D/E)XK endonuclease-like domain superfamily	Interproscan
IPR041677	Domain	DNA2/NAM7 helicase, helicase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10887	DNA2/NAM7 HELICASE FAMILY	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0017116	Molecular Function	single-stranded DNA helicase activity	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0017108	Molecular Function	5'-flap endonuclease activity	Interproscan
GO:0071932	Biological Process	replication fork reversal	Interproscan
GO:0004386	Molecular Function	helicase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K10742	DNA2; DNA replication ATP-dependent helicase/nuclease Dna2	EC:5.6.2.3 EC:3.1.-.-	DNA replication proteins	ko03032	deepkoala