Genomic Location: chr5:3674924...3696078
NR annotation: XP_031551093.1, focal adhesion kinase 1-like isoform X2 [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
ENSQPTP00000032810.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q00944 | Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2 |
| Q91738 | Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2 |
| P34152 | Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003173 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21477 all species → | FERM_C_FAK1 | FAK1/PYK2, FERM domain C-lobe | Domain | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| PF03623 all species → | Focal_AT | Focal adhesion targeting region | Domain | Interproscan |
| PF18038 all species → | FERM_N_2 | FERM N-terminal domain | Domain | Interproscan |
| PF07714 all species → | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR041784 all species → | Domain | FAK1/PYK2, FERM domain C-lobe | Interproscan |
| IPR049385 all species → | Domain | FAK1-like, FERM domain C-lobe | Interproscan |
| IPR000299 all species → | Domain | FERM domain | Interproscan |
| IPR017441 all species → | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| IPR005189 all species → | Domain | Focal adhesion kinase, targeting (FAT) domain | Interproscan |
| IPR036137 all species → | Homologous_superfamily | Focal adhesion kinase, targeting (FAT) domain superfamily | Interproscan |
| IPR001245 all species → | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR020635 all species → | Domain | Tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR041390 all species → | Domain | Focal adhesion kinase, N-terminal | Interproscan |
| IPR008266 all species → | Active_site | Tyrosine-protein kinase, active site | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46221 all species → | FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0004713 all species → | Molecular Function | protein tyrosine kinase activity | Interproscan |
| GO:0005925 all species → | Cellular Component | focal adhesion | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0007172 all species → | Biological Process | signal complex assembly | Interproscan |
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K05725 | PTK2, FAK; focal adhesion kinase 1 | EC:2.7.10.2 | Protein phosphatases and associated proteins | ko01009 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
