Genomic Location: chr6:3214557...3318077
NR annotation: XP_031550934.1, PC3-like endoprotease variant B [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
ENSQPTP00000034398.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| P29145 | PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE=2 SV=1 |
| P29146 | PC3-like endoprotease variant A OS=Hydra vulgaris OX=6087 PE=2 SV=1 |
| P63239 | Neuroendocrine convertase 1 OS=Mus musculus OX=10090 GN=Pcsk1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000150 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01483 all species → | P_proprotein | Proprotein convertase P-domain | Family | Interproscan |
| PF00078 all species → | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF00082 all species → | Peptidase_S8 | Subtilase family | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR023827 all species → | Active_site | Peptidase S8, subtilisin, Asp-active site | Interproscan |
| IPR002884 all species → | Domain | P domain | Interproscan |
| IPR034182 all species → | Domain | Kexin/furin catalytic domain | Interproscan |
| IPR036852 all species → | Homologous_superfamily | Peptidase S8/S53 domain superfamily | Interproscan |
| IPR015500 all species → | Family | Peptidase S8, subtilisin-related | Interproscan |
| IPR000477 all species → | Domain | Reverse transcriptase domain | Interproscan |
| IPR008979 all species → | Homologous_superfamily | Galactose-binding-like domain superfamily | Interproscan |
| IPR023828 all species → | Active_site | Peptidase S8, subtilisin, Ser-active site | Interproscan |
| IPR000209 all species → | Domain | Peptidase S8/S53 domain | Interproscan |
| IPR022398 all species → | Active_site | Peptidase S8, subtilisin, His-active site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42884 all species → | PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004252 all species → | Molecular Function | serine-type endopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0008236 all species → | Molecular Function | serine-type peptidase activity | Interproscan |
| GO:0005802 all species → | Cellular Component | trans-Golgi network | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0016485 all species → | Biological Process | protein processing | Interproscan |
| GO:0030173 all species → | Cellular Component | obsolete integral component of Golgi membrane | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01359 | PCSK1; proprotein convertase subtilisin/kexin type 1 | EC:3.4.21.93 | Chaperones and folding catalysts | ko03110 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
