Genomic Location: not available for this species
NR annotation: XP_031567931.1, son of sevenless homolog 1-like isoform X2 [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families
ENSQPTP00000037344.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q07889 | Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 PE=1 SV=1 |
| Q62245 | Son of sevenless homolog 1 OS=Mus musculus OX=10090 GN=Sos1 PE=1 SV=2 |
| Q07890 | Son of sevenless homolog 2 OS=Homo sapiens OX=9606 GN=SOS2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003123 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00169 all species → | PH | PH domain | Domain | Interproscan |
| PF00621 all species → | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF00618 all species → | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00617 all species → | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036964 all species → | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR000219 all species → | Domain | Dbl homology (DH) domain | Interproscan |
| IPR035899 all species → | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR000651 all species → | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR008937 all species → | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR023578 all species → | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR019804 all species → | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR001895 all species → | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 all species → | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 all species → | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 all species → | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03099 | SOS; son of sevenless | - | Endocrine resistance | ko01522 | deepkoala |