Genomic Location: chr9:12619025...12645176
NR annotation: XP_031557238.1, ras-specific guanine nucleotide-releasing factor 1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
ENSQPTP00000037999.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q13972 | Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens OX=9606 GN=RASGRF1 PE=1 SV=2 |
| P27671 | Ras-specific guanine nucleotide-releasing factor 1 OS=Mus musculus OX=10090 GN=Rasgrf1 PE=1 SV=2 |
| P28818 | Ras-specific guanine nucleotide-releasing factor 1 OS=Rattus norvegicus OX=10116 GN=Rasgrf1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001886 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00617 all species → | RasGEF | RasGEF domain | Family | Interproscan |
| PF00618 all species → | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR036964 all species → | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR001895 all species → | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR019804 all species → | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR008937 all species → | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR023578 all species → | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR000651 all species → | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 all species → | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 all species → | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 all species → | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
ENSQPTP00000037999.1.Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
