Gene detail

Detailed information of ENSQPTP00000039284.1 in Actinia mediterranea

Genomic Location: :...
NR annotation: XP_031572036.1, glyoxylate reductase/hydroxypyruvate reductase-like [Actinia tenebrosa]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1
Q91Z53	Glyoxylate reductase/hydroxypyruvate reductase OS=Mus musculus OX=10090 GN=Grhpr PE=1 SV=1
A1RYE4	Glyoxylate reductase OS=Thermofilum pendens (strain DSM 2475 / Hrk 5) OX=368408 GN=gyaR PE=3 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00389	2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Domain	Interproscan
PF02826	2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050223	Family	D-isomer specific 2-hydroxyacid dehydrogenase	Interproscan
IPR006139	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Interproscan
IPR029753	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site	Interproscan
IPR006140	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10996	2-HYDROXYACID DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0008465	Molecular Function	hydroxypyruvate reductase (NADH) activity	Interproscan
GO:0016618	Molecular Function	hydroxypyruvate reductase [NAD(P)H] activity	Interproscan
GO:0030267	Molecular Function	glyoxylate reductase (NADPH) activity	Interproscan
GO:0016616	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0051287	Molecular Function	NAD binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00049	GRHPR; glyoxylate/hydroxypyruvate reductase	EC:1.1.1.79 EC:1.1.1.81	Glycine, serine and threonine metabolism	ko00260	deepkoala