Genomic Location: not available for this species
NR annotation: XP_031569074.1, cytosolic isocitrate dehydrogenase [NADP]-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families
ENSQPTP00000039876.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q04467 | Isocitrate dehydrogenase [NADP], mitochondrial OS=Bos taurus OX=9913 GN=IDH2 PE=1 SV=2 |
| Q4R502 | Isocitrate dehydrogenase [NADP], mitochondrial OS=Macaca fascicularis OX=9541 GN=IDH2 PE=2 SV=1 |
| P48735 | Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001891 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00180 all species → | Iso_dh | Isocitrate/isopropylmalate dehydrogenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004790 all species → | Family | Isocitrate dehydrogenase NADP-dependent | Interproscan |
| IPR024084 all species → | Domain | Isopropylmalate dehydrogenase-like domain | Interproscan |
| IPR019818 all species → | Conserved_site | Isocitrate/isopropylmalate dehydrogenase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11822 all species → | NADP-SPECIFIC ISOCITRATE DEHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004450 all species → | Molecular Function | isocitrate dehydrogenase (NADP+) activity | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005777 all species → | Cellular Component | peroxisome | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006102 all species → | Biological Process | isocitrate metabolic process | Interproscan |
| GO:0006739 all species → | Biological Process | NADP metabolic process | Interproscan |
| GO:0000287 all species → | Molecular Function | magnesium ion binding | Interproscan |
| GO:0016616 all species → | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0051287 all species → | Molecular Function | NAD binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00031 | IDH1, IDH2, icd; isocitrate dehydrogenase | EC:1.1.1.42 | Central carbon metabolism in cancer | ko05230 | deepkoala |