Gene detail

Detailed information of ENSQPTP00000041586.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031560616.1, rap guanine nucleotide exchange factor 4-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

ENSQPTT00000022656

ATGGAAACCACCGCGCCCAAACTTCTTAGAGATCGCAAATACAACATGAAAGAATACCCAAAATGCTTTGTTGGCTCGGAGGCTATTGATTGGCTACTCAAGAAATCCAGGCTTGTTCACAGTCGCTTCCACGCGTTAAGTCTGTGGCAGGCGCTGCTTGAAGAAGGGACTTTAGCACATGTTACTCACGAGTACGACTTCCGTGACAAGACCCTTTATTACAAGTTTCTGGTGGATGAAGGCGATGAAGAAGGTTACATCCCCCTAGAAGGCGAGGAACTGGAAGATGAGTTTGAGGACGTCCTTATTATGCTGAGTAACGTTGGACCGGACGCCATGTTCAGAATGGCACTGAGGAAAGACCCCGACAAAAGAACTCAAGAAGACTTGGACGTTATCTATGAAGAACTGCTACACATCAAAGCATTATCCAATCTATCTACTATGGTTAAGAAAGATTTAGCTGCTGTTTTTGTGCTAGAAACATGCAAGAAGAAGGGAACCATGTTATTTAACCAAGGGGATGAAGGGAATTCTTGGTATATCATACTCAAAGGATCTGTCAATGTACTGGTGTATGGCAAGGGCGTTGTCTGTCAGCTGCGCGATGGAGATGATTTTGGGAAACTGGCCTTAGTCAACGACGCTCCCAGGACCGCAAGCATCGAGACATGTGAGGATAACTGCCAGTTTCTGAAGGTCGACAAGGATAATTTTAACAGGATTCTTAGGGACGTGGAAGTGAACACCGTACGCATGAAGGAACGAGGCAGAGACGTACTTGTGCTGAAACAAGTGAAAATAAGAAACCACTTTAGTGACAGGAGCCCTGTAGCAAAAACTACTCAGCAAAAGTACTCTGTCATGGCAGGGACACCAGAAAAGATGATTGAACATATTCTGGAGATGCGCATCGACAACAAAGAGGAGAACAAAACGGACAGTTTTCTTCTCGAGTTCTTAATGTCTTATCCAGTCTTCATGACGTCAGAAGCCTTGTGCATGGAGCTGTTAACCAAGTACCATGGCAGTGTGATCCTGGACGAACGCAAGGACAGTCACGATGAGAGTAAAAGCCAAACTAGTGACCGTAGTATAGTGGTCAAAAAAAGAGTGGCTCAAATCGTTATTCAGTGGCATAAATTGGCAAAAAACCTTCTTGTTGAAGATCACAGCTGTTTCTTACTGATCAATGATCTTATGTCAGCGCTGGAGGCAGACAAGCTGTTTGATGAATTGAACGCTTTGAAGAAAGATATGAACAAGAAGAAAGAGCAGGACACGGAAGTCGCAGATTCACAAATAATTTCCTGTCGTTCGTTGTCGTTCTCCGTCGGTTTTCGGGTTGGAAACACGAACATCTTCGAACGAACCAAGAGAACCGCTGGCAAACCAATATCACGTGACGACTACGttattttcaaagttttttgtGCTGATCATACCTACACTACGGTGAGACTGAAGTACGGTGACACAGCACAGAAGATCGTCGAGACAGCAGAAGAACGTGTCCTCCTTGGAGATGATTGTGTGCTCTGTGAAGTCAAGTCAAACAGCGAGATAATACCATACAAACCCGACGACATGTGTGTGGTCACCAGACTGAGTGTTAATGGCAGATTGTTCGTAGCACCGAGAGAACATCTTGATTCACTGACTCCACTTTCAGAGCAAGAAGGACCAGAACAAGGATCCTTCAATATTCTGGAGATGACAAGTTCAAGAGAGATAGCATATCACCTGACTGTGTACGACTACGAGCTGTTCACCAGTATCAACATTTATGAACTGGTTTACTATACGTTTGGTCGCGAAAGGTTCGACAAGATCACAGCCAATCTAGATCTGTTTCTCAAACGATTCAACGAGGTTCACTATTGGGTCATCACAGAGATCTGTCTCGCAAGCCAGATCAGCAAACGCGTTCATTTGTTGAAGAAATTCATCAAAATTGCCACACACTGCAAAGAATATCGAAATTGGAACTCATTTTTCGCTATAATTATGGGGTTAAACAATGTAGCAGTCAGCAGGTTATCACAGACTTGGGAGaaactaCCAagcaaattcaagaaaatgttcGAGGAATTCGAAGCATCACTGGATCCTTCTAGGAATCACCGCGTTTATAGACTAGCAATAGGAAAGATGAAACCACCAATCATACCATTCATGGCTCTACTTATGAAAGACATTACGTTCATCAATGAAGGCAATAAAACTTACTTTGATGACCTTGTAAACTTCGAGAAACTTCGGATGATCACCTCTACGTTACACCTGATTGAGTACTGCAGAAGCAAACCTTTTGTAGGAGAAGCTCCACCTTCCATCAAGAATGTCAATGAAATTGTAACATACGTCAGGACGTTACGTGTTAACGACAATCAAAGGAATTTAACACAGCTATCCCATCGCCTGGAGCCTCGGAAGAGTTGA

Transcript

ENSQPTT00000022656

agaACTCCTCCCATTCTCTCGTCCATGCTTGTCTCGTCTTTCGTCGTGTAATGGAAACCACCGCGCCCAAACTTCTTAGAGATCGCAAATACAACATGAAAGAATACCCAAAATGCTTTGTTGGCTCGGAGGCTATTGATTGGCTACTCAAGAAATCCAGGCTTGTTCACAGTCGCTTCCACGCGTTAAGTCTGTGGCAGGCGCTGCTTGAAGAAGGGACTTTAGCACATGTTACTCACGAGTACGACTTCCGTGACAAGACCCTTTATTACAAGTTTCTGGTGGATGAAGGCGATGAAGAAGGTTACATCCCCCTAGAAGGCGAGGAACTGGAAGATGAGTTTGAGGACGTCCTTATTATGCTGAGTAACGTTGGACCGGACGCCATGTTCAGAATGGCACTGAGGAAAGACCCCGACAAAAGAACTCAAGAAGACTTGGACGTTATCTATGAAGAACTGCTACACATCAAAGCATTATCCAATCTATCTACTATGGTTAAGAAAGATTTAGCTGCTGTTTTTGTGCTAGAAACATGCAAGAAGAAGGGAACCATGTTATTTAACCAAGGGGATGAAGGGAATTCTTGGTATATCATACTCAAAGGATCTGTCAATGTACTGGTGTATGGCAAGGGCGTTGTCTGTCAGCTGCGCGATGGAGATGATTTTGGGAAACTGGCCTTAGTCAACGACGCTCCCAGGACCGCAAGCATCGAGACATGTGAGGATAACTGCCAGTTTCTGAAGGTCGACAAGGATAATTTTAACAGGATTCTTAGGGACGTGGAAGTGAACACCGTACGCATGAAGGAACGAGGCAGAGACGTACTTGTGCTGAAACAAGTGAAAATAAGAAACCACTTTAGTGACAGGAGCCCTGTAGCAAAAACTACTCAGCAAAAGTACTCTGTCATGGCAGGGACACCAGAAAAGATGATTGAACATATTCTGGAGATGCGCATCGACAACAAAGAGGAGAACAAAACGGACAGTTTTCTTCTCGAGTTCTTAATGTCTTATCCAGTCTTCATGACGTCAGAAGCCTTGTGCATGGAGCTGTTAACCAAGTACCATGGCAGTGTGATCCTGGACGAACGCAAGGACAGTCACGATGAGAGTAAAAGCCAAACTAGTGACCGTAGTATAGTGGTCAAAAAAAGAGTGGCTCAAATCGTTATTCAGTGGCATAAATTGGCAAAAAACCTTCTTGTTGAAGATCACAGCTGTTTCTTACTGATCAATGATCTTATGTCAGCGCTGGAGGCAGACAAGCTGTTTGATGAATTGAACGCTTTGAAGAAAGATATGAACAAGAAGAAAGAGCAGGACACGGAAGTCGCAGATTCACAAATAATTTCCTGTCGTTCGTTGTCGTTCTCCGTCGGTTTTCGGGTTGGAAACACGAACATCTTCGAACGAACCAAGAGAACCGCTGGCAAACCAATATCACGTGACGACTACGttattttcaaagttttttgtGCTGATCATACCTACACTACGGTGAGACTGAAGTACGGTGACACAGCACAGAAGATCGTCGAGACAGCAGAAGAACGTGTCCTCCTTGGAGATGATTGTGTGCTCTGTGAAGTCAAGTCAAACAGCGAGATAATACCATACAAACCCGACGACATGTGTGTGGTCACCAGACTGAGTGTTAATGGCAGATTGTTCGTAGCACCGAGAGAACATCTTGATTCACTGACTCCACTTTCAGAGCAAGAAGGACCAGAACAAGGATCCTTCAATATTCTGGAGATGACAAGTTCAAGAGAGATAGCATATCACCTGACTGTGTACGACTACGAGCTGTTCACCAGTATCAACATTTATGAACTGGTTTACTATACGTTTGGTCGCGAAAGGTTCGACAAGATCACAGCCAATCTAGATCTGTTTCTCAAACGATTCAACGAGGTTCACTATTGGGTCATCACAGAGATCTGTCTCGCAAGCCAGATCAGCAAACGCGTTCATTTGTTGAAGAAATTCATCAAAATTGCCACACACTGCAAAGAATATCGAAATTGGAACTCATTTTTCGCTATAATTATGGGGTTAAACAATGTAGCAGTCAGCAGGTTATCACAGACTTGGGAGaaactaCCAagcaaattcaagaaaatgttcGAGGAATTCGAAGCATCACTGGATCCTTCTAGGAATCACCGCGTTTATAGACTAGCAATAGGAAAGATGAAACCACCAATCATACCATTCATGGCTCTACTTATGAAAGACATTACGTTCATCAATGAAGGCAATAAAACTTACTTTGATGACCTTGTAAACTTCGAGAAACTTCGGATGATCACCTCTACGTTACACCTGATTGAGTACTGCAGAAGCAAACCTTTTGTAGGAGAAGCTCCACCTTCCATCAAGAATGTCAATGAAATTGTAACATACGTCAGGACGTTACGTGTTAACGACAATCAAAGGAATTTAACACAGCTATCCCATCGCCTGGAGCCTCGGAAGAGTTGAAATACAATCAACACGTACATGCAGCATCAGAGAAAATCACTTGTTTATACACTTTCTCATACTAGTAAACCATAGACAAAACAACATTTTCAACTTTAAAATTACGAAAACGCTCCCTAGTTTCTGTTATGCAGGCAGCTCGGAAGCACGAGGGAAGAAAAATTACGTCACTGCAAAACTTAGGTGTCATGAAGAATGTGaaagcaaaaaatgaaaacctaTCCACCATTGCAaaactaatataaaactcaTTCGGTTATTGCCAGTTTCTGTTATCAACCTCTTATTAGCAACCTTAGTTGTGACACCttagttttgcaaattttctcgattctgaCTGGTTAACATTTTTTTCGGATCAGCTAGTTTGGAACACACCATGCAGCAGTTTCATATCTCAGATATGTTAAAAATCTTCTATACCATGTTGATACAAATGCGCTGCCGGCTTACGACATTTCACTGCAACTAATATCTTTCTATCCTAATGCCCATTTAGACGACAGAAATATAATTTCTGTGAGCAAAATTTTAAATCCAAAATATTAACTATATGTTTTACAAAATATATCCCAATATTTAATAAATTCCATACGATATTTTATCACGACAAGATTTCAAGAAAATTTTAATTGTGAAT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8WZA2	Rap guanine nucleotide exchange factor 4 OS=Homo sapiens OX=9606 GN=RAPGEF4 PE=1 SV=1
Q9EQZ6	Rap guanine nucleotide exchange factor 4 OS=Mus musculus OX=10090 GN=Rapgef4 PE=1 SV=1
O95398	Rap guanine nucleotide exchange factor 3 OS=Homo sapiens OX=9606 GN=RAPGEF3 PE=1 SV=6

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004421 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00610 all species →	DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain	Interproscan
PF00027 all species →	cNMP_binding	Cyclic nucleotide-binding domain	Domain	Interproscan
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan
PF00618 all species →	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000595 all species →	Domain	Cyclic nucleotide-binding domain	Interproscan
IPR000591 all species →	Domain	DEP domain	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR000651 all species →	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan
IPR014710 all species →	Homologous_superfamily	RmlC-like jelly roll fold	Interproscan
IPR008937 all species →	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR018490 all species →	Homologous_superfamily	Cyclic nucleotide-binding domain superfamily	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113 all species →	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007265 all species →	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04351	RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.