Genomic Location: not available for this species
NR annotation: XP_031565207.1, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families
| CDS |
| ENSQPTT00000002883 |
| Transcript |
| ENSQPTT00000002883 |
| Protein |
| ENSQPTP00000043322.1 |
| UniProt accession | Description |
|---|---|
| P0C1Q2 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Mus musculus OX=10090 GN=Pde11a PE=1 SV=1 |
| Q8VID6 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Rattus norvegicus OX=10116 GN=Pde11a PE=1 SV=1 |
| Q9HCR9 | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Homo sapiens OX=9606 GN=PDE11A PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000883 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00233 all species → | PDEase_I | 3'5'-cyclic nucleotide phosphodiesterase | Domain | Interproscan |
| PF01590 all species → | GAF | GAF domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR023174 all species → | Conserved_site | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | Interproscan |
| IPR002073 all species → | Domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | Interproscan |
| IPR003607 all species → | Domain | HD/PDEase domain | Interproscan |
| IPR036971 all species → | Homologous_superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | Interproscan |
| IPR003018 all species → | Domain | GAF domain | Interproscan |
| IPR023088 all species → | Family | 3'5'-cyclic nucleotide phosphodiesterase | Interproscan |
| IPR029016 all species → | Homologous_superfamily | GAF-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11347 all species → | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008081 all species → | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0004114 all species → | Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0004118 all species → | Molecular Function | 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0010754 all species → | Biological Process | negative regulation of cGMP-mediated signaling | Interproscan |
| GO:0043951 all species → | Biological Process | negative regulation of cAMP-mediated signaling | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K13298 | PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 | EC:3.1.4.17 EC:3.1.4.35 | Cushing syndrome | ko04934 | deepkoala |