Gene detail

Detailed information of ENSQPTP00000043929.1 in Actinia mediterranea

Genomic Location: chr10:10226047...10232944
NR annotation: XP_031568954.1, hexokinase HKDC1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000053174

tTAACGTGAAATTTTGTTCAATGAAATTATTTATGTGGAATAcagttttatatatttaaataatgtgACGCAAGGAATTCGGAAATACTTCGGGTGCTTGATGTATCAGTCGATAATCCTCCGTCAAGTGTTATTAGGCTATCGTTACGAACCTCACATCAGATTACAAAATTTGCGAAATTTGGACTTGACGCGAAAGCATTCTCTTCTACCGGACAGGACGAATAGCTAGAAAAGAAGAACAATTTCAAGTTCGGTAGCTCTATTTTCAGATATCATAGCCATAAATACAAGTCAAGATGTTTAGTGTACCGCATTTATTATCCAATGCCTTTAAGTCACTGCAGACCAACCTCTCCGGAGCAGATGAGGTTGAAGAACTTCTTAAGTCTTATGATCTCCCAAAGGAATCACTAGTTGAGGTTATGAGGATTCTGAGGTGTGACATGGACAAAGGATTGTCTGCAGATCCTAATATCAGGTCTGAAAGCCCAATCAAAATGCTACCAACATTTGTACGTTCAATACCAGACGGAACAGAGTCAGGAGATTTTCTAGCTCTAGATCTTGGAGGGACAAACTTCAGGGTCTTAATTGTACAGATACTTCACGGCAAAGTACAAATGGATAGTGAAGTTTTTCCACTCAGTaaaacaatcatgaccagtgaTGCCATCACTCTCTTTGACTACATTGCTGACTGTATCATGCTCTTTGTCAAAAAGAAAGGACTTAAAGATAAAACACTTCCTCTTGGATTTACCTTCTCCTTTCCAGTAGAACAGTTTAGTTTGGTATCAGGGAATTTAATCCGTTGGACCAAGGGTTTCAGTGCTGTTGGGGTTGAAAATGAAGATGTGGTCAAGCTACTCAAAGATGCTCTGTCAAGGAAAAAGAGTGAATCTGTTGAGGTTGTTGCACTGGTAAATGATACCACAGGGACAATGATGTCATGTGGTTTTGACGATCGCAATGTCGTTGCTGGTCTAATCCTGGGAACGGGCACCAATGCCTGTTACATGGAGAAACTAGACAAGGTAGAGAAGTGGACTGGCGATCAGAACAATCCTAGACAAGTTATCATTAATACAGAATGGGGAGCATTTGGAGACAATGGACTTTTGAACTTTATTGTTACTGATCATGACAAGAATGTGGACAGTGGTTCTATTAATCCTGGACAGCAAATCTTTGAGAAAATGATATCAGGAATGTACTTGGGTGAGCTTGTCCGTCTTGTCTGCCTTGATCTCCACAAAAAAGGACTTCTGTTTAAGGGAAAGAGCTCCAAGAAACTAGAAACCAAGTGGGGATTCCTCACAAAATTTGTGTCTGACATTGAAAGTCATGACAAAGCGAAAATTCGACAGACAGTCCAAGAACTTGGAATTGAGGGCTCTGAGGAGGATTATGAGACATTGAAGAAAGTCTGTAGTGCATTGTCTCAAAGGGCAGCACGTCTGGCGGCAGCAGGTCTTGCAACTATTGTTGAGAAAACTGAGACATACGAAAGCACCATCGCTGTGGATGGCAGCCTGTTCAAATACCACCCTCAATTTAAAGCTTACATGCAAGCAACTATTAAAGAACTACTACCAACAAGCAACATCAAGTTGATGCTATCTGAGGATGGTTCAGGCAAGGGTGCAGCTCTGATAGCAGCTGTTGCCGCAAGGATTTCCAAATCACATGCATAAGGAATGGATTGATTTTGAGTTAATGAGCATTACAACCGTATATAGCACACTCAATATACAGTGCACAACCAACACACCAGGGTTGTGGTGTTTTACACAACccaagaaacaaaacaaaaacagaagGAATCTTACCTTTGTCAAGTCAGGTACATTCAAAATGTATAGTAGAAAATggggaaggaaaaaaaaacatggatTTGGATATAATACATCATAATAAATGTATCTATTTTATACAACTCATTATGTCAGTCATTGTTGCTGCCATTATTTCAGTTTAAATGCCAGCAGATCTAAAGTTTGGCAAGCAAGATATTTGGTCaaagattaaaatattttctcattcAGTCACTATGAACAATGAGGGTAAGACCTATGCTTACCCTCTAAATTATTTGTTTCCATTGATATTGTGATCAACCTACAACATTCAGTATTACACAACTACCAATACCAACACCCTTACCGTTACATTATTGACCACTCAACTCACAGACCCAACATCTTGGGAACATGTTACTTTCAGTTTTGAAAAACTCATGAATCTCACATCCTGAGTGGATGGGAAtgcatgctttatgagagcacagtGTGCACACCCATGCACACTGGTGCCCATCATTCATTGTTGTGAAGCACTCGTCTACCAATCCCCACTTTACAACTGCATACAGCAATTGTGAACAtgccttttatttcttctctaAACTCTTGAGCTCAACATCTGTGAGTAGAGAAGTCATCTGTTGATTCTCTCTCTCACTGGGAGTGATTTAAATCAACTATTAATGTTAGTCCAATAATAGAATAAGAAAATTCTATTGTCTTATTTTGTTTACTGTGATTTTAAAATTACAAGACTTTGTTTGACTTGGgattaaaatcattttaagagtttttctctgggtccaatttttttcccttatGCAAAAATCATTTAAACATTAATTTACATTATCTGCAAGGGTTGATccagggggggcaaaggggggcttc

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P05708	Hexokinase-1 OS=Rattus norvegicus OX=10116 GN=Hk1 PE=1 SV=4
P27595	Hexokinase-1 OS=Bos taurus OX=9913 GN=HK1 PE=2 SV=1
Q91W97	Hexokinase HKDC1 OS=Mus musculus OX=10090 GN=Hkdc1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002477 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03727 all species →	Hexokinase_2	Hexokinase	Domain	Interproscan
PF00349 all species →	Hexokinase_1	Hexokinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR043129 all species →	Homologous_superfamily	ATPase, nucleotide binding domain	Interproscan
IPR001312 all species →	Family	Hexokinase	Interproscan
IPR022673 all species →	Domain	Hexokinase, C-terminal	Interproscan
IPR022672 all species →	Domain	Hexokinase, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR19443 all species →	HEXOKINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0001678 all species →	Biological Process	intracellular glucose homeostasis	Interproscan
GO:0004340 all species →	Molecular Function	glucokinase activity	Interproscan
GO:0004396 all species →	Molecular Function	hexokinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0005536 all species →	Molecular Function	D-glucose binding	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0006006 all species →	Biological Process	glucose metabolic process	Interproscan
GO:0006096 all species →	Biological Process	glycolytic process	Interproscan
GO:0008865 all species →	Molecular Function	fructokinase activity	Interproscan
GO:0046835 all species →	Biological Process	carbohydrate phosphorylation	Interproscan
GO:0051156 all species →	Biological Process	glucose 6-phosphate metabolic process	Interproscan
GO:0016773 all species →	Molecular Function	phosphotransferase activity, alcohol group as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00844	HK; hexokinase	EC:2.7.1.1	Glycolysis / Gluconeogenesis	ko00010	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →