Gene detail

Detailed information of ENSQPTP00000044037.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031561560.1, probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

Transcript

ENSQPTT00000053295

ACAAGTACAGatcttgggctgcctgtggttttACTTCACATCCCAGGCCCTCCTTGTCATGTTTGTCTGAGCTCATCGTCACAGCGTCCCTTTCTCTTCATAGATTCCACGTCGGTGTCGATAGATTCACGTGTGTGGAAGTCATTTGAACAAATATTCTCTTATTTTATTCCAAACCATGTATCGATTTATATCTCTAAGCCGTAAGGCATCTCCATTGTCTACAGCATGCAGACGATACATGAGTAATGGAAcgCCAGCAACCACCAAGCTTTTTATAAATGGAGAATTCATGGAGTCCAAAACTTCTAAATGGATTGATCTTCACAATCCAGCCACAAATGAAGTAATCACACGGGTACCAGAGTCCACACCAGAAGAGATGCAAGCTGCCGTAGACGCAGCCGCAGCAGCCTTCCCTGCCTGGTCTGAAACATCAATATTGGCACGACAACAAATCATGTTTAAGTTTCAACAACTCATCAAGGAAAACATGAAAGAACTTGCCCACAACATAACACTAGAGCAAGGAAAGACACTTCCAGATGCAGAGGGAGATATCTTGAGAGGATTAcAGGTTGTTGAGCACACATGCTCCATCACCTCTCTTCAAATGGGGGAGACAATGCAGTCTGTCACTAAAGACATGGATACTTATTCCTACAGAGTACCTTTGGGTGTTTGTGCCGGAATCACTCCgttCAACTTTCCTGCTATGATTCCACTTTGGATGTTTCCAGTAGCTGTTGTTTGTGGTAACACATACGTCATTAAACCCTCAGAAAGAGATCCTGGTGCATGTATGATGCTGTTGAAGATGGCGCAGGATGCTGGAATGCCTGATGGCGTAGTGAATGTTATCCATGGAGCAAGAGACGCTGTCACTTTCATCTGCGACGACCCAACTATTAAGGCTATCTCATTTGTAGGGTCCGACCAAGCTGGAAGGTACATCTATGAACGGGGCAGCAAGGGTGGCAAGCGAGTACAGAGTAACATGGGAGCCAAAAACCATGGTGTCATCATGCCTGATGCCAGTAAAGAAAGCACCATAAATCAATTAATAGGAGCTGCATTTGGAGCTGCAGGTCAGAGGTGTATGGCCTTGTCTACTGCTATCTTCGTAGGAGAGACTAAAGAATGGATCCCAGAGATTGTTGAGAAAGCCAGGAAACTTCAAGTCAATGCAGGTGATCAACCAGGAGCAGACTTAGGACCAGTTATTTCACCACAATCCAAAAAGAGAATCTGTGACTTGGTTCAGTCTGGTGTGGACCAAGGAGCTAAGATGGAGCTTGATGGCAGAGATGTTGTTGTAAAGGGATATGAAAATGGTAACTTCGTTGGTCCTACTATCCTGTCTGGCGTTAAGCCTGAAATGACGTGTTACACAGAGGAAATCTTTGGGCCTGTCTTGGTTGCATTGGATGTCGACACAATGGAAGACGCAATAGAAATCATCAACAAAAACCCATATGGCAATGGCACAGCCATATTTACCAACTCTGGTGCAGTCGCTCGCAAGTTCCAACAGAAAGTCGACGTTGGTCAGATTGGTGTAAATGTTCCAATCCCAGTACCTTTGCCAATGTTCTCTTTCACTGGATCACGTGGATCTTTCCTTGGTGATGCTCACTTCTATGGAAAACAGGGAATTAACTTCTACACTGGgacaaaaacaataacaagTCTGTGGAGAGACGAAGACGCGAAGCCACAAAAAATTCGAACTTCGTTCCCTCAAATGAAATAAGAAGCGAGTTGAATAACTTTGTAATAATGTATTATCGATATCGAACTCTTCATTAACTACACTGACAAAGAAAAGGACGAACTGCGCTctaagcttttaaaatatgaTGTAATAATAAGTAATGATTTTTGTTAAAGTCAGTTTTACCTTAAGGACACTCGAACCGTGAGTACTTCGAGTTTCTTTCACGTTATTATTTTCTGAACTTTCTACTGTTTCAAACCCTCTGAAATGAAACGCAGAGTTAAAATACACCGAGatatcaaaataaattttacttTAGATTGGCTCAAGGGATGATTTACAGTACGTATTTtggaaataacaaaaaactcGAAATGTTGACGGTTCGAGCTCTCTCACTGTAGTCAAATAGTATAATCATTAGAGTGTAATCTAATGGGACTTGTGGCTTTTCtaacttatttattgtttaagTAGTTAAAAGTTTCCTTggtttccttgtttcctttcCCTTCTTCAACAGCCGTAACAGTCTAAAGGCATTTATTCTCGATTCTATGTTAAAAAAGCgcgtggaaaaaataaaaaatacttttcaaatTATCGTCGTTCTTCAGTGGTAAATTGTAGAAACCGGCGTCTGAGAAACCTTTCAAGTTGACACAAGACAGTCCGTATCACTGAAGAGCTTTAAATCTATACCAAAAAATTGAACTAAAAGATTCCATTTGCGAcaaaaattatgaaaatttaCTCCTTTGGTTTTTCGTGTCcttagaaaaatagaaaacttaGAAGCTTTTCTTTCACATACCGTGCCTTCCCA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q07536	Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Bos taurus OX=9913 GN=ALDH6A1 PE=1 SV=1
Q17M80	Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Aedes aegypti OX=7159 GN=AAEL001134 PE=3 SV=1
Q02253	Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Rattus norvegicus OX=10116 GN=Aldh6a1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004167 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR016160 all species →	Conserved_site	Aldehyde dehydrogenase, cysteine active site	Interproscan
IPR010061 all species →	Family	Methylmalonate-semialdehyde dehydrogenase	Interproscan
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43866 all species →	MALONATE-SEMIALDEHYDE DEHYDROGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0004491 all species →	Molecular Function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0006210 all species →	Biological Process	thymine catabolic process	Interproscan
GO:0006574 all species →	Biological Process	valine catabolic process	Interproscan
GO:0018478 all species →	Molecular Function	malonate-semialdehyde dehydrogenase (acetylating) activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00140	mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase	EC:1.2.1.18 EC:1.2.1.27	beta-Alanine metabolism	ko00410	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.