Genomic Location: chr10:9360583...9361419
NR annotation: XP_031555379.1, methylated-DNA--protein-cysteine methyltransferase-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
| CDS |
| ENSQPTT00000053533 |
| Transcript |
| ENSQPTT00000053533 |
| Protein |
| ENSQPTP00000044258.1 |
| UniProt accession | Description |
|---|---|
| Q6TDU1 | Methylated-DNA--protein-cysteine methyltransferase OS=Canis lupus familiaris OX=9615 GN=MGMT PE=2 SV=1 |
| P16455 | Methylated-DNA--protein-cysteine methyltransferase OS=Homo sapiens OX=9606 GN=MGMT PE=1 SV=1 |
| P26187 | Methylated-DNA--protein-cysteine methyltransferase OS=Mus musculus OX=10090 GN=Mgmt PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0008732 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01035 all species → | DNA_binding_1 | 6-O-methylguanine DNA methyltransferase, DNA binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036217 all species → | Homologous_superfamily | Methylated DNA-protein cysteine methyltransferase, DNA binding domain | Interproscan |
| IPR014048 all species → | Domain | Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding | Interproscan |
| IPR036388 all species → | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR001497 all species → | Active_site | Methylated-DNA-[protein]-cysteine S-methyltransferase, active site | Interproscan |
| IPR036631 all species → | Homologous_superfamily | Methylated DNA-protein cysteine methyltransferase domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46460 all species → | METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0003908 all species → | Molecular Function | methylated-DNA-[protein]-cysteine S-methyltransferase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00567 | ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase | EC:2.1.1.63 | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
