Gene detail

Detailed information of ENSQPTP00000047444.1 in Actinia mediterranea

Genomic Location: chr12:8992086...9020091
NR annotation: XP_031572515.1, general transcription factor IIH subunit 1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000056975

CATGCCGTCatcaaagatggcggctgACAATGAAGACTCGAAGTTGTTGGAAGTAATCAATAcgaaatacaagaaaaatccCGGAACTCTACGCCTTCTCACTAACACATTAACATGGACTCTTCATGGAAGCAACGCAGCCAAAATAGACTGCAAATATTCGGAGATCAAAGTTCAAAGAATAAGTCCTGACAGCAGTTCCAAGGTTCAGCTGCAGATTGTTTTACACGATGGTAGCTCCTATAGCTTTCATTTTACCAACACTTCTGAGCCAAAAGCAAGACAGGAACGAGATGAAGTCAAGGAATTACTGGCTCAGTTGATACCTGCACACCGTATGAAAGCAACCAAGGAATTAGAGGAGAAAAACAAGATACTAAAAGAAAATCCAGACATATACCAGCTATATAAAGATCTCGTTGTCAGTGGTGTTATAACATCTGAAGAATTTTGGGCCAACAGAGGAAAGGTAGTTAGATCTCTTAAAGAGGATGATAGTGATATTCAATCAGTTGGATTGTCTTCAAATCTATTGGGGGACGTCCAGCCTGAGAGCTCAGGATGTAATGAAGTTAAATACAACTTGAATGCTGACACTATTGAGTCAATATTCAAAACCTATCCGGCAGTTAAAAAGAGACATGCAGAATCTGTTCCTGATAAGatGACAGAAAAAGAATTCTGGACAAAGTTTTTTCAGTCTCATTATTTTCATCGTGATAGATCTGCAAGTGCTAAGCAAATGGGTACTGACATGTTTACACAATGTGCCATTCAAGATGAACAAGAACAACTTGCTAGTAAATTGTCTGAGttcaaagacccaatcctggATCTTGCAGAAGCATCGCCTTTACCAGATGAGgGTTATGGTATTGTAGCAGGAGACCTTCCAGAACAGGCTGCCAAAAACTCGTCATCTGGACAGTCATTGTTTCGCCGACTTAACCACCATAGTTTAATGGTCTTACAGACATTACAGTCAGCAACGAATACAAAAGTACCTGAAGCAGAACAAAATGGAGAAGTCAAATCAAGTAAAGAACCTCCGACTAAAAAGAGTCGATTACGCGAGATATTAGAGTACGAGGATCTTCAGGAGAGAGAGGCAGAAAAATTACAAAGTCTAAAGATTCCTAGTACGAACACGTATGGCGTGGGGCATACCGTAGATAATGTTGAGAATGGATTTTCGAGTCATTCAAATGAAAGTACTATAGACGACCAAACAGCACTAcaatattgtaaatatgaaACAGAAAACTGGGTTCCACGTTTAACTCAGGTTCTTTCAAGTGACCAGGCTTGTCACGTACTCACAGAAATGTCACCTGGAGGTTCTTTGATGGAAAGCACCTCAGATATCAACATGCAACATATGGTGTCAAGTTCCGTCGAGAAAGAAATCAAGGATCAATACAATGCTCTAGCGGAACTACTTAGACATTTTTGGTCGTGTTTTCCGACGAAAACTCCTTCGCTAGAAGAAAAGCTCGTGCGAATGGGTAAAAGTCTTGAAAAGTATCGTGATAACAATCTGGTGCACCTGAAATCTAAACTGCCCCAAGAAGAGTCTCACCTGACAAACCACCTTGATCAAATGATAGAAGCCGCCACCACGAAATTCAGAACCTGGGAATCCAAAAGATCAAATCCAAGAAGCTTAACCAGCTGACAGTGCTACAAGGTCAGCGGTCATGCGATGAAACTTTCCGTTACCATGTTTTTCATGTACAAAAACAGGTTCAGCAAGTagattttctatatttttcagTCTATTTTAGTTTCGTCCTTAAAAATTCCTACAGTCTAAGCTCAAGAAGTAAGAAATTTGTAATTTACTACTGAGCCTGCGTTTCTGGATGGTCTGCGAGTATTTTTCAACCGCTGACCGCCAAGTCTGACATTCAGAGTAGAAGTTtagttattttctatttcttaccGCGGTATGGTATCCTGGATACCGGATAAGTGCTATTGCTAAAAACCAACAAAGCGGCAAAACAAGAtgaaaagcaaataaaaataataataataaaaaagaaaaaaaagaaaaagaaaagttattttacGTCCAAACTGTGCCCTTGGCCTTGAAAACGTGTATTTAAggctccgtccacactatgccggataaatttgaatccgaatttttatttatccggttaggcctaccgtccacattAGTCcaggcgaatccggaacaattcttcaccgaaaacgaatattttcgaatacggtctccaaagtttaacaaattgaaaacgccggctagccgtattagtgtgg

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9DBA9	General transcription factor IIH subunit 1 OS=Mus musculus OX=10090 GN=Gtf2h1 PE=1 SV=2
P32780	General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1
Q960E8	General transcription factor IIH subunit 1 OS=Drosophila melanogaster OX=7227 GN=Tfb1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004728 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03909 all species →	BSD	BSD domain	Domain	Interproscan
PF08567 all species →	PH_TFIIH	TFIIH p62 subunit, N-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005607 all species →	Domain	BSD domain	Interproscan
IPR035925 all species →	Homologous_superfamily	BSD domain superfamily	Interproscan
IPR027079 all species →	Family	TFIIH subunit Tfb1/GTF2H1	Interproscan
IPR013876 all species →	Domain	TFIIH p62 subunit, N-terminal	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12856 all species →	TRANSCRIPTION INITIATION FACTOR IIH-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000439 all species →	Cellular Component	transcription factor TFIIH core complex	Interproscan
GO:0005675 all species →	Cellular Component	transcription factor TFIIH holo complex	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0006289 all species →	Biological Process	nucleotide-excision repair	Interproscan
GO:0006351 all species →	Biological Process	DNA-templated transcription	Interproscan
GO:0006360 all species →	Biological Process	transcription by RNA polymerase I	Interproscan
GO:0006366 all species →	Biological Process	transcription by RNA polymerase II	Interproscan
GO:0070816 all species →	Biological Process	obsolete phosphorylation of RNA polymerase II C-terminal domain	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03141	TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1	-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →