Gene detail

Detailed information of ENSQPTP00000047803.1 in Actinia mediterranea

Genomic Location: chr12:1415072...1421682
NR annotation: XP_031574969.1, NACHT, LRR and PYD domains-containing protein 3-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQPTT00000057382

ATGGCAACCAGTTGTGCATCTTCAAGTAAAGAAAATCTAAACTTTTTTCGTCTTTCAAAGCTTTTGATTGATGGTGGAACACATGTCTTAAAAGATGTATTCGACTCCATGCATTCACCGAGCTCTCTTGTCAGCACATTAGGTGATACAGTAGTACATTCTACTCTAAAGGGACTGAGAACAAAGAGGATTCTAACCACTCAACAATGGGACAGACTCTACCCTGCCAGTACAAGTACACCTGTCACTTCAGCAGATTTTGACATCACACTGTTATTTGTTCTACTGCGTAATATATGTAGTTTAACACCCCCATCAACAGGATGGGACAAGCCTCCTGTTGCTACAGACCTGAGTACAGAAGCCGATTTGGCTCGAGTCAAATATTATAGAAATGAACTTTATGGTCACATCACAAAAACAGCTGTTAGTGatagtgattttgaaaaatactgGAGTGAGATCTCTGATGCGTTGGTGAGACTGGGTGGACCTCATTACAAACCAGAGATTGAGAGGATGAAGATAGAAGCAATGGACCCtgaagaggaaaagaaatattctGAAGTACATAAGGAGTGTGAGAAAATGGAGCAGAGATTACTTGAAAGGATGGAGGAGCTTCTTACTAAGCAAGTGAAAGGGAATTCAaGACCTGTTCAAATGCTCGATACTGGGGAATATACAGAAAGACTGAAGTCATCCATTAAACAACAAACCGATTTTCTGTTGTCAGAGGAAGAAGACAAGAAAATAAGAACCGACGACATCTTTACGAGTGTGACTATCCTACGTGGTCCAAAACGCTTCAAGGAGCCCCAAGAGGGAGAATTGGATGAAATTCAAGCATGTAGTACAACACTCAAGAACTGTTCAGAAATGTTTCTTTGCCCAGAAAATAATGATCAGCAGTCCACAGCTTCTTGCACGACCAATCCTAAATCTATCTTGTTGACGGGCAAAGCAGGAATTGGAAAATCCCTTTTTTGTCGGAAGCTGGCACGGGATTGGTCGCATAACCAATTGTTTGAGGAAGGTCAAGAAAATGCCAAAGTACCCGATTTTCAGTTTGTGTTTCTGTTGACATTCCGTCAACTTCTTCTtctagaaaaagaagaagaaagggttGACTTACGTGATATCTTAAATCAGTCCTCCCTACTGAACGAACACTCGGTGATAGACGAGCCATTACTGCAGTACATGATTGACAATCCTGAGAAGCTGCTCATCATCcttgatggttatgatgagtATAAAGATCGAGAGAAAATCACCAGTGACTTTGAGACAGCATGTTCAAAGGACCGTAATGAAAAAATACCTGTTCCTGCTCTGATTGCCAAAATCATGAAAGGAAAGATGTTAAACGGTGCAGTGGTCCTGATATCCTCGAGGCCTGGCGAAGCAGaggaattaaaaaaacttcTCTTTGATGTAAGATGTGACATTCAAGGATTTTCTTCACTTCAAGTGCTAGAATACatcgaaaaatatttcaaagtcaacGAAAGCATGAAGAACAAAGTACTCGATCACATCAAAAcgaatgaaattcttttgagTTTTGGTCACATTCCTGTGATGTGTTTTCTAATGTGCTACTGCATTAAGTGGTACATGACTGAATCAAAAACCACAGAAAAACTACCCGTCACAAGAACACAACTTTATCATGAAGTAATCAAAGTATTTATTAAGAAACATTCCTCTTCTAAATATGAAGAAATGGAAGAAACTAAAGTAcaagaaatattacaaaaactAGCTGAACTAGCGATGAATTTAATGATGgaagataaatatattttcaacgAAGAGGATatgaaaaaattcaatctTAACGATGAAGAAATAGCAAACCTGAAAGCGAGTGGATTACTTGACTGTTGTCCTGGCGTTAAAAAATCTCCATTCGAGAAACCACCACTTGAATTGACGTTCACCCACCTAACGATTCAAGAATTTCTTtgtgcttttttgtttgtagagaaaaaacaaatcccagagaaaaagaaaacgagcGATGTAACATTTATGTTCATGGCGGGAATGTgttcaagagaaaaagatgaaaaacagATGGAAAAGTTAATAGAAAATACCAAACCAGAGGACAAAGACGATCATAGGAATAAACTGCTAACTTTATCCTGTCTGTACGAGTACAAAGATGATGGATTTTCTACCAGAGTCATAAATAACCTTAAACAGGTATACTGTAATAGGGATGGGGAGATtgaatttagaaaaataacAGATATTGATTGTCTGTTCataagttatttattagaTATAGTGAATTTAATCAACGAAGAACAAACTAAACAACATCCAGCATTTACGCAGCCTtttattgttcattcattGTGCATTGAGTGGTCAACTTTATCAGCATCAGGGATCAGAATGTTGTGTAATTCTCTTGCTAATATTTCTGCTGTTGATGAGCTGTCGCTGTGGGCTTGTGAACTAGTAGATGATGaatgtattaaaataatttgtgAACTGTTGCCTAGTACTAAGATAACATGCCTATACCTAAGTAGGGACAATATAACAGATATTGATGTTAAACAAATATCTGACATGTTGCCTCGTACTAATATAACCCTCATAGAACTAAGTGATAACAAAATAACGGATGTTGgtgttaaaataatatgtgaCATGTTGCCTCGTACTAATGTAACACAATTATACCTACATAATAATAAGATAACAGATGTTGGTGCTCAGTGTCTATGTTCAGTATTAACACGTGATGATTGTCGTGTAAAAGAGTTAAAATTACAGGGTAATAACATATCAAGTGAATGTGAACTGTCTCTAAGACAACAACTGATCCCTGGTGTTGAGTTGATTATTTAG

Transcript

ENSQPTT00000057382

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A0A386CAB9	NACHT, LRR and PYD domains-containing protein 1 homolog OS=Danio rerio OX=7955 GN=nlrp1 PE=1 SV=1
P59046	NACHT, LRR and PYD domains-containing protein 12 OS=Homo sapiens OX=9606 GN=NLRP12 PE=1 SV=2
Q86W26	NACHT, LRR and PYD domains-containing protein 10 OS=Homo sapiens OX=9606 GN=NLRP10 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000079 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF05729 all species →	NACHT	NACHT domain	Domain	Interproscan
PF17779 all species →	NOD2_WH	NOD2 winged helix domain	Domain	Interproscan
PF13516 all species →	LRR_6	Leucine Rich repeat	Repeat	Interproscan
PF18738 all species →	HEPN_DZIP3	DZIP3/ hRUL138-like HEPN	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR007111 all species →	Domain	NACHT nucleoside triphosphatase	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR032675 all species →	Homologous_superfamily	Leucine-rich repeat domain superfamily	Interproscan
IPR041075 all species →	Domain	NOD2, winged helix domain	Interproscan
IPR001611 all species →	Repeat	Leucine-rich repeat	Interproscan
IPR041249 all species →	Domain	DZIP3-like HEPN domain	Interproscan
IPR050637 all species →	Family	NLRP family, innate immunity and inflammation regulators	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45690 all species →	NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSQPTP00000047803.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →