Gene detail

Detailed information of ENSQPTP00000053496.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031565143.1, rap guanine nucleotide exchange factor 6-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

ENSQPTT00000063663

ATGAAAGCCATGGGAGGTTACCTGGAGTCATCTGTCAGGGTCATGTCGCAGACTGCAAGATACGAAGAATATGACTCAAATTTCCTTCTTTATCAttCCAATGACTATGCTTCCTGTTGGTATATTTTACTCACTGGTTGTGTGTTTTTAGAAGGATGCATGTATCTACCTGGAAGCagtttTGGTAAACAGCCCCATGGTGCAGATGGTACAAGGGGAACTGACTGTCTGGTATTAGAGCGATCTGGAATGATAGTGATTGATTATCCTCATGAGAATCTCCTACAACCATTCCAAAGACATTCTTACTCAACTTCAGAGCTTGAAAAGCTCCTTGCGCTTGAATCAAAGGATTTTCTTGTAGGAGGACCAGTTCCTGAAGATGAAAAGCTTCCAATGGAATTGCAACAAGTAAAGGATATCTTGCTACGAAGTGAGCACAATctaaagaaaaaggaagataaagaaaacaaggCACATGCTGCACTAGAAACAAAATACAGTCACTCCTCTGAACACTTAGAGCTGGACTTATCTGGACTGGTAGAGAGTATTGttgATTCTGATGATGAAGAGGAATCTGCTTCCCATTCTTCACAAGAGTCTTTCATGGTCAGAGATGTCGTTCGAGACTGCCTGGAAAAAGAACCCTCGGAAAGAACCGAGAGTGACATTGGTAAGCAAACTGATTGCTGTTTTATTGCGTTCGCGAACATGACGCAGAACGTACGTCGTGCTCTGTGTGCTGTCATGGTGTTTGCAGTGGTGGAGAAGGCTGGCTCGGTTGTCATGGAGAATGGAGAAGAGCTTGATTCTTGGTCTGTTATTCTCAACGGCTCAGTCGAGATTTTTGTCGATGGAAAAGAGACAACGTGTCTCCATCTTGGCGATAGTTTTGGTGTTGAACCGTCCCTGAAGAAGATGTTACACAAGGGCGTGATGAAAACACGTGTAGATGACTGTCAGTTTGTGTGCATCGCTCAAACAGACTACTACCGAATCCTGACCCAAGGCAAGTCAAACGTCAAGGTCATAGAAGAAGGGGGCGAGGTTGTCATGGTGACGGAACATCGAAGTACGGATGGTGGTAACAGAGAAGGAGAAGTTGTAATCAAGGCTAAACCAGAAAAGCTGATATCCCATTTGGTAGAGGATCATTCAGTTATCGATCCAACGTTCGTGGAAGATTTCCTTCTAACATTTAAAACCTATTTCGACCAGCCAAGCCAGATCTGCGGGCGTCTTCTGTCCTGGTTTCTCAGTAAAGACTATCGCGATAAGGTAACTCGAGTGATGCTTCTATGGGTCAACAACCATTACACCGACTTTGAAGGTGACACCGCCATGGAAAACTACCTCGAGACGTTTGAGGTGGGACTTGAACAACAGAAAATGAGTGGTCAATTAGACTTACTGAACATGGCGTGCTCAGCCAAGGCAAAAAGCCGCGTTATCGACCGTCCCTCGTGCAAGCATAACTGGGGGTTCTGGATGGCTGGAGGAAAAGAAATGTCACTCCCGATTTTCGTTTCCAAGGATACATATGTTTTTATATCTAAGAATTTCTCTCTTGGATTTCCAGGGTTTAAAGAGCTACAATCTTCACCTGTTATTGTAACAGGAGACCATGCAAAGAACGACAACCATGGAATTGAAAAGCCCGAGTATGTCCAACGTAGCTCTTCTGATTGCACAGAGAAGAGGAACCATATGCAAACACGACTCTCAGCTCCTGATATAACCTCAGGTATGTCACTCTATATTCCTATGCAAACTCAATCCAAAACTgataaagtaaagaaagcCCTGACGAAGTTTTCAACATTGGGTTCTCTTTCAAGACAGTACAAGTTAATATCGAAGAGTGATCGTGATCTGACAAGTGTTGATTCTGGTTTTCACGAGGGAGACGAGGTTCATAACTCAGCTAGATTAGGGGTTAAAGTGCGCACTCGTGGCTCTATTCCCAGAGCATTTGGATCCATGGAAAGCCTTAATACAGTAGAGGGCCAGACTAACGAGTACCCTGATAAGGTTCTGAGGGTGTATAAAGCTGATCAAACAAGCAAATACTTCCTTATATACAAGGAGACAACAGCAAGAGAAGTCATCGATATGGCACTAGAAACGTTTGGTCTTCCAACAAATGCTACAGAAGAGTATTCGCTATGTGAAGTCACTGTAGAAGAACATGGTCTTGTACGACAAAGGCGTCTACCTGATACTCTAACAAACCTGGCTGATCGAATTGGCTTGAATGCTAGATATTACTTAAAGAATAACATGGAGACTGCGCAGTTGTTACAAGGAGATGCAACGCAGGAATTAGCAAAAGAAGGACAAGTGACTTTGTTAGGATTAAATACTCAAGAGGTAGCGAAACAACTTACTTTAAAGGATTTCGAGTTGTTACGAAGCGTAGATTCCCGCGAGTACATCTATGATGTCTGGGAATTCCCTCCAGAATTATGGACCAATCTAAGCAAGTTCTCAGACATTGTTAACTACGAGACGATGTGGGTGGTCACCGAGATCTGTAGTGAACCTAGTCTAGTCAAAAGAATGAAGCTTATCAAACACTTTATCAAAATAGCAAAATATTGTAAAGACTGTAAAAATTTTAACTCTGCATTTGCGATTATAAGTGGATTGGCTAACATGTCTGTAAGACGGTTAAAGAATACATGGGACAGACTACCGACTAGATATAACAAGATGTACGAGGATCTCGAGAATCTGATGGATCCTTCGCGCAGTATGTTCAAGTACAGAAGTCTCGTAAACAGCGCAAACGTTTCACCGCCATTGATTCCGTTTTTCCCCGTCATTAAACGAGATCTGACTCTGATTTACCTCAACAATAAGAGCGTGATTGACGGCCTTGTGAATTTCGAGAAACTTCGTATGATAGCAAGAGAAGTTCGACAAGTCGTCAAGTGTCATTCAGTACCATATGACCCCGCGACCATGTTCGACCAGGATTCTAATGCCTCCCAGAGTAAGACATCACAAGTCGTTGGCATGGTAACCAGTGGTACCACGTGGGGACGTCGATCTTTAGCACGTGACCAGAACCCGAAGAAAATGTTTGAAGAGGCTGTGATGACAAGGCGTGTCCAAAAATACCTGGACAATCTTCTCGTTATTCTAGATGAAGATAAACTACGAGAAATGTCCAATGCGTGTGAACCCGCACAGGGGTCGGGTCCACCTAGTGTACAAACTAGACGGAAAAACTCTCCAGCAACCTCACCTACAGtagtgaaaaaagaaaagaaaaacagcaaCAGACAAACAGCTGACCGCATATCTGTCTCCTCTACAACAAGTACATCGTCGTCTCTCCCTGATCCCCACTCGCCCAGACCAGTCTACGAATCACGTAAGTGTCGATGGTGTTGCACCACTCATTACAAACCACGTGACCACTTCCTTGAGCATCACGTGGCTAATAGAAGACGCGTACTCATCTTAGTACAGCACTGTCCTATTTCAGAATATATGGTCATTTTTTAA

Transcript

ENSQPTT00000063663

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8TEU7	Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2
F1PBJ0	Rap guanine nucleotide exchange factor 2 OS=Canis lupus familiaris OX=9615 GN=RAPGEF2 PE=1 SV=2
F1M386	Rap guanine nucleotide exchange factor 2 OS=Rattus norvegicus OX=10116 GN=Rapgef2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002715 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan
PF00618 all species →	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan
PF00788 all species →	RA	Ras association (RalGDS/AF-6) domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008937 all species →	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR019804 all species →	Conserved_site	Ras guanine-nucleotide exchange factor, conserved site	Interproscan
IPR000595 all species →	Domain	Cyclic nucleotide-binding domain	Interproscan
IPR000159 all species →	Domain	Ras-associating domain	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR000651 all species →	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR014710 all species →	Homologous_superfamily	RmlC-like jelly roll fold	Interproscan
IPR018490 all species →	Homologous_superfamily	Cyclic nucleotide-binding domain superfamily	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113 all species →	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0007265 all species →	Biological Process	Ras protein signal transduction	Interproscan
GO:0016324 all species →	Cellular Component	apical plasma membrane	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08018	RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2	-	Tight junction	ko04530	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.