Gene detail

Detailed information of ENSQPTP00000054576.1 in Actinia mediterranea

Genomic Location: :...
NR annotation: XP_031565509.1, egl nine homolog 3-like [Actinia tenebrosa]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9H6Z9	Prolyl hydroxylase EGLN3 OS=Homo sapiens OX=9606 GN=EGLN3 PE=1 SV=1
Q91UZ4	Prolyl hydroxylase EGLN3 OS=Mus musculus OX=10090 GN=Egln3 PE=1 SV=1
Q62630	Prolyl hydroxylase EGLN3 OS=Rattus norvegicus OX=10116 GN=Egln3 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13640	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan
PF01753	zf-MYND	MYND finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005123	Domain	Oxoglutarate/iron-dependent dioxygenase	Interproscan
IPR051559	Family	Hypoxia-inducible factor prolyl hydroxylases	Interproscan
IPR044862	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan
IPR002893	Domain	Zinc finger, MYND-type	Interproscan
IPR006620	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12907	EGL NINE HOMOLOG-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008198	Molecular Function	ferrous iron binding	Interproscan
GO:0031543	Molecular Function	peptidyl-proline dioxygenase activity	Interproscan
GO:0071456	Biological Process	cellular response to hypoxia	Interproscan
GO:0005506	Molecular Function	iron ion binding	Interproscan
GO:0016705	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418	Molecular Function	L-ascorbic acid binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K09592	EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase	EC:1.14.11.29	Renal cell carcinoma	ko05211	deepkoala