Gene detail

Detailed information of ENSQPTP00000056140.1 in Actinia mediterranea

Genomic Location: chr15:812392...828357
NR annotation: XP_031550346.1, sphingosine-1-phosphate lyase 1-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000066657

GTTGAGTGATAGAAAGAGCGAGTCGCAGAAAAGTCAACttctcttccttcttttcGTCCGATCGGCTTAAAAGTTCAACATGATTGAGTTAAATCTCTGGGAAAAATTCCTAGGGAAAGTAGAGCCCCATCTACCAGAATATTTACACTGGAATGAAATTTGTTGGACTTTCGTCTTTTACCTTGCAGAAGCAAGGCGTCATATTCACCGATGGACACGAGGAATGGAGCCTTGGGAGATTGTGGTAAACACAGTGTCTATATGTTTCTGTGCTTTTCTTGCATTTGAAATTTTACGTTGGTTTATAAGCTGGATTTTCTTCCAAGATGAAAGTTTTTATTcaagaatgaaaaagaaaacgtttaGGATCATTAGAAGTCTTCCAATCATCAGAGATAAGATTGATGCCGAAATGCAGAAAACATTAGATGATATGGAACAAATGGCCTTTCCATTACATGAAGGGCAAGTATACAGAACCAAGTTACCATACAAAGGTCTTAAAGAGGCAGAACTCATGactgaaatagataaatatggCAAAATGGTGGAGATTGATTGGGAAGCTGGTCATGTGTCTGGTACAGTGTACAACGGAGGCAAAGAACTGACTCAAGTTTTGACTAAAGTTTATGCCAAGTTTGCCTGGTCAAATCCTCTCCATCCTGACGTCTTTCCTGACGTGCGAAAGATGGAAGCTGAAGTTGTTCAAATGACTATTGCAATGTTTAACGGTGGAGAAGATGCTTGTGGGACTATGACAGGTGGTGGTACAGAGAGTATTCTGTTAGCTTGCAAGTCATACAGAGATTGGGCACATGAACGAGGAATTCAAAAACCTGAAATTATTGCACCAGTAACTATCCATGCTGCTTTCGACAAGgcAGCTCATTATTTTGGTTTCAAGCTTGTCCATGTACCTGTAAATGAAAAGACGTGGATGTGTGACCTTAGGGCAGTTAAAAGAGCAATAAATCGCAACACCATTGCTATTGCTGGCTCAGCTCCTCAATTTCCACATGGTATTTTGGACCCAATAGAAGAAATGGCCAAACTTGCAAAGAGATATAACCTTGGTATGCATGTCGACTGCTGTCTTGGTGGGTTCTTAGTTCCATTTATGGCAAAAGCTGGGTATCATCTGCCACCTTTTGATTTTAGTGTGGATGGAGTTACTAGTATATCTGCTGATACTCACAAGTATGGATACTCGCCCAAAGGATCTTCAGTAGTGTTGTACAGTAACAAACATCTGAGGCACTTCCAGTTCTTCGTTGCTCCTGACTGGCCTGGTGGTATCTATGCCTGTCCTTCTATCCCTGGCAGTCGTCCTGGTGGAATTATTGCAGCTACATGGGCCGCCATGATGTACCTGGGAGAAACGGGATATGTAGACTGCACAAAGAAGGTCATCCAGACTAGAGAACAAATACAGAAAGGtcTTAGCAAGATAAAGGGATTGTTTGTCTTTGGTGATCCTAAAGTTAGTGTTGTAGCATTTGGATCTAATGATTTCAATATCTATGCTCTCGGTACTCAACTCACTGAACGAGGATGGTGCCTAAACTCCCTCCAAAAGCCTGCAGCgATTCATTTCTGTGTTACCCTACTAAGCACCCAGCCAGGAGTAGTGGATAAGTTCTTGAAGGATTGCAGGGAATGTACTGCTAAACTGATTAATGATCCGAACGCAAAGACCTCTGGAATGGGTGCCATATATGGTATGGCCCAGAACATTCCAGATCGTTCTATGGTGTCAGAGTTAGCATGTGGCTTCCTGGACTGTATGTACAACACCAAGAACCCAGGACTGAAACCCATATAGAATAGTACCAGATAGAATGACCAGGAACTGTGGCTGCCTCGACCAGATATCTTATGGTGGCTGGTCATCTTAATTATATGAAGATATTCAAACGACAGTTATTCTATGCGACAATAATTATATCAAAGTGTACGTGTATTTGGTTACGACTTTTGGATCTTGAAGGAAATTCTGATAAAATGAAAGGAATAATTTTCTAACTAACacatgaaatttaaaaactagAATGACTTGAGTTTGAGAGAGTTTTGATATGTGCTCTTAGTATAAACCTACTTTTGGTCTATCACAAATCCtgcactctgattggctgagctgCTAGTAATCTATCAGTGTTAGACCACTAGTAGAGAAAATTGCCAGTCTTAAACTGAAGCAGCTCAAAAACTAAATCATTTCGATCTTATCTCAAAAATTGTTTATACCCATTTATTTGACCATTTAGTAGGTTTatactaaggccccgtccacacgtatccggaaattttttttgcggatacaggttgcgtccacacgtatccgaaaatttttgtgtccgtatccggaaattttacgaaaacggatacgtgtggacggtgaaaacgattcaaatacgctgcgtgtggacgcaaacattttcgtatccgcaaaaaataatttgcggatacaaaaatttccggatacgtgtgaaacaaaacaataaggTCAGCCTCATGGGCTATTAACTCGTAAACCATTGTTTATTAGCCATCCTGGGGGTAAGGAAAAAACGGTCAAGTTGGAGAAGAAGTGCATTGCAGGAGTGTTTTAGATGACGTCCATTTTATGCCCtaaacagccccaaaatgcactgcaatgcttactcgacccagttttcccctcgacccagttttcccctcgacccagttttcccCTCGACCCAGGAATGGCAAGCTGTTTGTATAATACTTTTTAACATACATGTAGCTGTCGTTATTCTCATTCCAATTGGTCAACTTCATTCGTTAAGGTGACATTTTT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8R0X7	Sphingosine-1-phosphate lyase 1 OS=Mus musculus OX=10090 GN=Sgpl1 PE=1 SV=1
Q8CHN6	Sphingosine-1-phosphate lyase 1 OS=Rattus norvegicus OX=10116 GN=Sgpl1 PE=2 SV=1
O95470	Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003263 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00282 all species →	Pyridoxal_deC	Pyridoxal-dependent decarboxylase conserved domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015421 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, major domain	Interproscan
IPR002129 all species →	Family	Pyridoxal phosphate-dependent decarboxylase	Interproscan
IPR015422 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, small domain	Interproscan
IPR050477 all species →	Family	Group II Amino Acid Decarboxylases	Interproscan
IPR015424 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42735 all species →	-	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016830 all species →	Molecular Function	carbon-carbon lyase activity	Interproscan
GO:0019752 all species →	Biological Process	carboxylic acid metabolic process	Interproscan
GO:0030170 all species →	Molecular Function	pyridoxal phosphate binding	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0008117 all species →	Molecular Function	sphinganine-1-phosphate aldolase activity	Interproscan
GO:0030149 all species →	Biological Process	sphingolipid catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01634	SGPL1, DPL1; sphinganine-1-phosphate aldolase	EC:4.1.2.27	Sphingolipid signaling pathway	ko04071	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →