Gene detail

Detailed information of ENSQPTP00000058935.1 in Actinia mediterranea

Genomic Location: chr2:991109...997651
NR annotation: XP_031568381.1, phosphoenolpyruvate carboxykinase, cytosolic [GTP]-like isoform X1 [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000069730

AAGTACGTGCAATTGCCAtaattcttttctttgagCTGTTTACATAGAAATAATTTGAAGTTTGATATATTCGTGCCACGAAACACGACCATGGTGTTAAGACACGGTCACGTGTTGTATCTGGACCAATCAGGCCCCAGTTAACGACCTTTGGACTGTGTTCCAGTGGAAGTCATTTCGTCACTACCTACGAATGCAGGCAACGGAGACGTGAGGCGTCACGATTCTCGAATCCTTTATAGTTTAGTATTTATATCTTCTCCTCTCAGTAGTAATGTCATTAGTCTCTCTGATTACTAGGCTCCCGAGGTCTTCGTCGTCCAGATCGTTGCCAATTCGTTATCGTTTAATACTTCGAACCATGTCTTCTCTGCCTCCATTCGAAAAAGGTGATCTGAATTCTCTGTCAAGCAAAGTTCAGGAGTTCGTTTCTGGCTATGCCGAGATCTTCAAGCCACAGAACATCCATATTTGCGATGGCTCCAACGAGGAAAATCAAGAACTGATAGATAAGCTGATAAAAGAAGGGGCTTGTGTTCCACTTACCAAGCATGATAACTGCTACGCCATAAGAACTGATCCCAAAGATGTAGCTCGTGTTGAATCCAAGACATTTATCTGCACGGAGAATCGTTACGATGCAGTACCTCATGTCAAAGAAGGAATACAAGGCGCTCTAGGTCGCTGGATGTCGATAGACGACGCTGAGAAAGAACTTGAAACGCGATTCCCAGGCGCCATGGTCGGCCGTACTATGTATGTAATGGCTTACAGTATGGGACCTGTAGGCTCTCCTGTATCCAAAATTGGTGTACAGATCACCGACTCTCCCTACGTAGTATGCTGTATGCGTATTATGACACGAATGGGAGCTAAAGTCATGAAAGTGCTTGGTGATGGAGACTTCGTGAAATGTGTCCATACGGTTGGATTCCCTAATGACGGCAAGAAGCAACCAACTGTTCCATACTGGCCTTGTGATCCAGAGAGAACCTTGATTCTGCACTTCCCTAAGACCAGAGAGATCAAGTCATTTGGTAGTGGTTATGGAGGGAACTCTCTGCTTGGGAAGAAGTGTTTTGCATTGAGGATTGCTGGTAATATTGCTAGAGATGAAGGATGGTTGGCTGAACATATGATGATTATGGGCCTGACAAACCCAGAGGGAAAGAAGAAATACATTGCAGGTGCTTTCCCCAGCGCATGTGGAAAAACCAACCTTGCCATGTTAACCCCTACTATTCCTGGCTGGAAAGTAGAATGTGTTGGTGACGATATTGCCTGGATGTGGTTTGATGAGGATGGCCAACTGCGTGCTATCAATCCAGAGAGTGGATTCTTTGGTGTTGCTCCGGGCACATCAAAAAAAACCAATCCCATCGCAATGAAGACTTTTGAGAAGGACACCATTTTCACCAATGTCGCTGAAACTTCTGATGGTGACTTCTGGTGGGAGGGTCTTGATCCACCAAAAGAGGGAATAACAATCAAATCATGGTTGAATCAGGAGAACTGGACCCCTGATAAGGGTTTTGCAGCTCACCCTAACTCCAGATTCTGTGCCCCAAGTGATCACTGCCCAATCATGGACAAGGACTGGGAGAATCCTAAAGGCGTCCCAATCAGTGCTATCTTGTTTGGTGGGCGTCGTCCAGTTGGCGTCCCACTTGTCTACCAGGCCTTTAATTGGCAACACGGTGTGTTTGTTGCTTCTTCCTTGTCATCTGAAACAACTGCTGCTGCAGAATTCAAGGGCAAGAACATCATGAGAGACCCTTTTGCCATGAGACCATTCTTTGGGTACAACTTTGGAAAGTACCTTGAGCATTGGCTTGGTATGCAGAAGAAATCTGACAAATTGCCTCCTATTTTCCATGTCAATTGGTTCCGTTTAGATGATAATGGGAAATTCTTATGGCCAGGTTTTGGAGAAAACTGCAGAGTTCTGGAGTGGATATTCAAGCGTTGTGATGGTGAAGACCTTGCAGATGTGTCTCCAATTGGCTATATTCCCAAGAAAGATGCTATCAATACCGAAGGCCTTGGAAAGATTGACATGGATGAATTGTTATCTATCCCTAAAGATTACTGGATGGATGTACTGAAGAACCTGCGTAAATACTGGGACGAACAAGTTGGGGAGGATTTACCAGGTCCTGTGAATGACGAGTTCAAGGCTCTGGAAGAACGCCTCAAGGCTGCAAAGTAAAACCTTGTCTTAAGCAATGGCAGCAGAGTTAGAACGGATTTCACAAATGTTGTATCTCACAATTTTAAAGACAGATAAACTATTGATAAATTAGGTATATCTTCAGTGGAACCTGTGTGGTCTTAAGAGATGTATTTATATAATACTCTAGTGATCAAAAAAACCCACAACATTcaagttattttttttttttgttatgctATCATAGGAAGGATTTTGTACAGTTATGTTAACCGTTTGGTTTTAGTTTTGTTTAGGTTAGTACTTTTGATCTATTGTTATTCTGAAGAATCCAACTAAGTTGAGATTTTGGtcaaacattttttgtttgtttgtttgtttgttttctgaCAGAGTTTTTCATTTAGTTCGTTTATGGTTTTACACCTTGAATAtcatattaatttatttcacCTTTTTTTCCtccaatttataattttttctcaCTTAGTGCCCAGATTGCCTTTCACTAATgacaataaatattaaaatgtcTACAATTTATCATGTTAAACATAAACAGtaacaaaaattcaaaactgtTGAGCGCAAACCATATATTTGTGGAatagcacaaaaactaaatagcaAGAAACATTTTGTCCATTAGGTTGTACCATTTCAAGTATAATGGCTTGGGCTCTAATTAGAACATGTGTCTAGCTATATAGTAAAGAGTTTGTATGGTTAAATATTTTCAgactaaaaattca

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P07379	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Rattus norvegicus OX=10116 GN=Pck1 PE=1 SV=1
Q5R5J1	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Pongo abelii OX=9601 GN=PCK1 PE=2 SV=1
P35558	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Homo sapiens OX=9606 GN=PCK1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002283 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00821 all species →	PEPCK_GTP	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	Domain	Interproscan
PF17297 all species →	PEPCK_N	Phosphoenolpyruvate carboxykinase N-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008210 all species →	Homologous_superfamily	Phosphoenolpyruvate carboxykinase, N-terminal	Interproscan
IPR008209 all species →	Family	Phosphoenolpyruvate carboxykinase, GTP-utilising	Interproscan
IPR035077 all species →	Domain	Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain	Interproscan
IPR013035 all species →	Homologous_superfamily	Phosphoenolpyruvate carboxykinase, C-terminal	Interproscan
IPR018091 all species →	Conserved_site	Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site	Interproscan
IPR035078 all species →	Domain	Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11561 all species →	PHOSPHOENOLPYRUVATE CARBOXYKINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004611 all species →	Molecular Function	phosphoenolpyruvate carboxykinase activity	Interproscan
GO:0006094 all species →	Biological Process	gluconeogenesis	Interproscan
GO:0017076 all species →	Molecular Function	purine nucleotide binding	Interproscan
GO:0004613 all species →	Molecular Function	phosphoenolpyruvate carboxykinase (GTP) activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0019543 all species →	Biological Process	propionate catabolic process	Interproscan
GO:0030145 all species →	Molecular Function	manganese ion binding	Interproscan
GO:0033993 all species →	Biological Process	response to lipid	Interproscan
GO:0042594 all species →	Biological Process	response to starvation	Interproscan
GO:0046327 all species →	Biological Process	glycerol biosynthetic process from pyruvate	Interproscan
GO:0071333 all species →	Biological Process	cellular response to glucose stimulus	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01596	E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP)	EC:4.1.1.32	Insulin resistance	ko04931	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →