Gene detail

Detailed information of ENSQPTP00000058990.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031568364.1, nibrin-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

CDS

ENSQPTT00000069790

ATGTGGAGCTTGTTTCCCAAGATCTCAACCTCAAATAGCCAAGATTCTGTTAAACTACTCACAGGAAAAGAATATATCGTAGGGAGAAAAGATTGTGCAGTATTGATCAAGGATGATCCATCAATCAGTCGCAAGCATGCTGTAATCACTGTCCAACATGATATCTCTAACTTGGGAGATCCCTCTAAGATACCAGAAGTAATGCTTACAGACAAATCAAAGTATGGAATATCTGTTAATGGTGTCAAGATTACTCAGCCAACTAGACTCAATAATGGTGATGAAATACTCTTTGGCAATCATCATAGCTGTTATAGATTAACTTACACTCCCTTGGTAGTGGTCACTTCATGTCTTGATAACACTAAGAAGAAGCCCCTCAAGAAACAGATTCATTTATTAGGCGGACATGTTTTAAATGATTGGAAAAGTGGATGTGTGACTCATTTGGTGATGGATGGGCTGTTATTCACAATAAAGGTTATCCATGCTCTTGCTGACTGTTGTTCCATAGTCACACCCAGCATCTTTAATGAAATCGTGAAGGCAATTGAAACATCAAGTGGGTTACCTATGCCAGACGAgTTTTTGCCTCCTCTTAAAGAAGAATCAATCAAGTCTGATGGACCTCTGTTTCTTGCTAATAACAGAAGAAAAACCTTGTTTAGTGGAAAGACTTTTATATTTCTTAGCAACAAGCAAtacaaaagaACACATGCAGCCATCGAGATGTGTGGTGGGAAGACTCTACTCAAGGATTCAGTAACAGATAATGAAGAAGATAAGAGAATGTTTGTAAATGATGGTTGTTGTGTGATGATGGTTGATcaaaaagaaagggaaagcTACCCAATGGATATGAAGCAGTGGATTACACAAATAATGGATTTCTTGAAAAATCACGACAAAAGACCTATTCCTGAATCAGAGCTTGGTTTGGCAATTTTACAAATGACGCTCACAAACTACTGTAATCCAGACATCGATGCAGTGCCAGCGTTGACTCAGAACATTGTCTGTCAGTCACTAAATGTCGGGCTGGACGAAACGTCGCAAGTCTTTTCACCGCAACACAAAGCACAAGCTAATCAGAAAAGTTTTAAGAAGCCCCAGTACCCATCTGAGGGAGAAGATGCTGACAAGACGCCTGATATAGTGTTTCTTAGGACTACTGAAGCAAATCAGTCAAGCACTACAAGCAAAGTTGCCGAACCTGATCACATTTCTCCAGAACGTGGTACAAAAAGAACGAAGAAACATGTTTATGAGGGTGTCGTTTTAGATACCGAGGACAATACACCCAAGGCACAAAAATCTAGACCAGACGTTAAGATAAGTCCTATACCAGATACCTTAAATATAAGCGGTAAAGACACGAATGTCTTGGTTGTAGAGACTCCTATCAAAGATACTAAGGAGAGGTGTTCATTATTTCCAAGCACTGCAGAGAAAAAGAGTGTCATCCCAGATAGCGAGGGCCTTGATTCTAGTAAAACAACTAGAGGACTACCTGAAACTCGGAATGAAAATTTGGATGGGAAAATAAAAGGAACGTCAATGGAAAGAGGGTCCTTAAACACTAGCAAATTAGATTTCATTCCAGATAGTATGGGAATGGATGTCAGTTCCTTGGCACCACAGAACGGTGTTAATAGTTCCCAACACGATAAGGAAGAATCTAAATGTAGACCACCCAAACGAACAAGAGTGTTAGATAGTACAGAGGAAACGGAAAGTCAAAAAGAAGATATCCCTACGAAACGAGCTAGGAATGAATCAGTTTTCAGGTCACCAGAGCAAGTACCCTCTACTGAAGGATATAGCAGTTATGATAACAAGAAAGGAGGTTTTgaagacgatgatgataatactaAAGAACAGCTATTCGGAAACATGGATGAGCTTGAAGAGAATGGAGCGCAATCGGATATTAAACCTGTGTTACCACGGCTTGAGGAGAGAGTTGATGGATTCCTGTGTACGAAAATACTCGGAAGGCAAATAAAAACAGAAGTTGAAGACGACGGTCTACCAAGAAACCTAGTTGTCGTAGATGTGGTGTCTCTTCTTGTCCGCAAACCCAAGGCACAACAAGCTGCACCTCCAACACGAGTTACTGGGAAAAACTTTAAGAAGTTTAGAAAGCAATGGTATGCTGGATGTGAAAGACGATTTCCTAAGATCATCGGTGGTAGTGACTTAGTGGTACATCAGACATCTACCGGCATTGATCAAGAGGACTGGTTCATTGAAGCAAGAGAGGCCAACAAAGAACAAGACAGAAGAGACAAGATGGAGGAACAGCTATTTATGTCAGACGCAGGCTTGCCTCAAGGAAGAAAACGCCGAGGAAGATAA

Transcript

ENSQPTT00000069790

GTGGAGATTAAATCATTTAGAACATTTCACCCCACATTTTTTAGTGCTTTTTGCGAGCAGTTGCaaccggaaatacgtcacaacttaaaaactcttttaaaaaatccatttGGGTTGTCTGTGGATGGCATATATTTGGCGCGAGACTTCAAGAAGGAAAGTAAAGAGTATAAAAGCTGGAAAATGAAAACTTTTACGCATCAGAATTGAAATACTGGACCGTCTATCCTCCTACTTGAACATGTGGAGCTTGTTTCCCAAGATCTCAACCTCAAATAGCCAAGATTCTGTTAAACTACTCACAGGAAAAGAATATATCGTAGGGAGAAAAGATTGTGCAGTATTGATCAAGGATGATCCATCAATCAGTCGCAAGCATGCTGTAATCACTGTCCAACATGATATCTCTAACTTGGGAGATCCCTCTAAGATACCAGAAGTAATGCTTACAGACAAATCAAAGTATGGAATATCTGTTAATGGTGTCAAGATTACTCAGCCAACTAGACTCAATAATGGTGATGAAATACTCTTTGGCAATCATCATAGCTGTTATAGATTAACTTACACTCCCTTGGTAGTGGTCACTTCATGTCTTGATAACACTAAGAAGAAGCCCCTCAAGAAACAGATTCATTTATTAGGCGGACATGTTTTAAATGATTGGAAAAGTGGATGTGTGACTCATTTGGTGATGGATGGGCTGTTATTCACAATAAAGGTTATCCATGCTCTTGCTGACTGTTGTTCCATAGTCACACCCAGCATCTTTAATGAAATCGTGAAGGCAATTGAAACATCAAGTGGGTTACCTATGCCAGACGAgTTTTTGCCTCCTCTTAAAGAAGAATCAATCAAGTCTGATGGACCTCTGTTTCTTGCTAATAACAGAAGAAAAACCTTGTTTAGTGGAAAGACTTTTATATTTCTTAGCAACAAGCAAtacaaaagaACACATGCAGCCATCGAGATGTGTGGTGGGAAGACTCTACTCAAGGATTCAGTAACAGATAATGAAGAAGATAAGAGAATGTTTGTAAATGATGGTTGTTGTGTGATGATGGTTGATcaaaaagaaagggaaagcTACCCAATGGATATGAAGCAGTGGATTACACAAATAATGGATTTCTTGAAAAATCACGACAAAAGACCTATTCCTGAATCAGAGCTTGGTTTGGCAATTTTACAAATGACGCTCACAAACTACTGTAATCCAGACATCGATGCAGTGCCAGCGTTGACTCAGAACATTGTCTGTCAGTCACTAAATGTCGGGCTGGACGAAACGTCGCAAGTCTTTTCACCGCAACACAAAGCACAAGCTAATCAGAAAAGTTTTAAGAAGCCCCAGTACCCATCTGAGGGAGAAGATGCTGACAAGACGCCTGATATAGTGTTTCTTAGGACTACTGAAGCAAATCAGTCAAGCACTACAAGCAAAGTTGCCGAACCTGATCACATTTCTCCAGAACGTGGTACAAAAAGAACGAAGAAACATGTTTATGAGGGTGTCGTTTTAGATACCGAGGACAATACACCCAAGGCACAAAAATCTAGACCAGACGTTAAGATAAGTCCTATACCAGATACCTTAAATATAAGCGGTAAAGACACGAATGTCTTGGTTGTAGAGACTCCTATCAAAGATACTAAGGAGAGGTGTTCATTATTTCCAAGCACTGCAGAGAAAAAGAGTGTCATCCCAGATAGCGAGGGCCTTGATTCTAGTAAAACAACTAGAGGACTACCTGAAACTCGGAATGAAAATTTGGATGGGAAAATAAAAGGAACGTCAATGGAAAGAGGGTCCTTAAACACTAGCAAATTAGATTTCATTCCAGATAGTATGGGAATGGATGTCAGTTCCTTGGCACCACAGAACGGTGTTAATAGTTCCCAACACGATAAGGAAGAATCTAAATGTAGACCACCCAAACGAACAAGAGTGTTAGATAGTACAGAGGAAACGGAAAGTCAAAAAGAAGATATCCCTACGAAACGAGCTAGGAATGAATCAGTTTTCAGGTCACCAGAGCAAGTACCCTCTACTGAAGGATATAGCAGTTATGATAACAAGAAAGGAGGTTTTgaagacgatgatgataatactaAAGAACAGCTATTCGGAAACATGGATGAGCTTGAAGAGAATGGAGCGCAATCGGATATTAAACCTGTGTTACCACGGCTTGAGGAGAGAGTTGATGGATTCCTGTGTACGAAAATACTCGGAAGGCAAATAAAAACAGAAGTTGAAGACGACGGTCTACCAAGAAACCTAGTTGTCGTAGATGTGGTGTCTCTTCTTGTCCGCAAACCCAAGGCACAACAAGCTGCACCTCCAACACGAGTTACTGGGAAAAACTTTAAGAAGTTTAGAAAGCAATGGTATGCTGGATGTGAAAGACGATTTCCTAAGATCATCGGTGGTAGTGACTTAGTGGTACATCAGACATCTACCGGCATTGATCAAGAGGACTGGTTCATTGAAGCAAGAGAGGCCAACAAAGAACAAGACAGAAGAGACAAGATGGAGGAACAGCTATTTATGTCAGACGCAGGCTTGCCTCAAGGAAGAAAACGCCGAGGAAGATAAACGTCCTGTACTGTTGTCATGCCAGCAGTAGTTCCAGTCCCAAACAGTGTTATATAAACCAATCAGGACCAAGGGTCCGAGGTTTTTGTTAGATTGAGAAGAAAGCAATActacaaaaaagaagaaaaaagaaataaagaaataaactaAGAAAAATTAAGCGGACGCCTTCGGGACTTTGCCTGGTGTTCGCTTAATGTAGGCTCGTTTTTGACAGTAAATGTGGACTGAAAATGTGCCAATGTTCGCTTGATCAAAGGTTGCATGCACTCATGATACAGTAGCCTGCGTAGCCAGGCGTTCCTTGTGGGTTTTTGGGAGGCTTTtgactccccccccccccaaataaaaacCTTCCCAAAACCCACAAGCTTTGGATTATCGGCTTTTCCCCCGAATTGTTGTGAACTTTCGCTGATTGGATTCTCGTTGTCCATAATGCATTTTGTGACTTGAAATCCAACATGTTCTTGCAACAAAACCGTGTAGCTTGTACAGGGGATTGCAAAAGCACCGCCTTTGTTACGGGTCTTTTTTTTACACACTAGAGGTTATGTAGCAGGGACATGGCCCAGAAACATGCAACAGCGACAAAATCAAGTCCTTTACACACGAGGGGACATGTAGTTTGGAcctgcggtcgccacatgtcaattgagtttgtttgatgtgttgttctctcctgttctacgagggttttttcctccgtaaaaatcaacatgtaagCCGTTCGTTGCataaaatagtaataatgtAGTCGTAGTGAGTGTGAGTGAAAGCAGGCCCACATCAGCGAGAGCTGCCAAAATAATTAGCCTGCTTTaacaaaaattgtttttctcaaaaaaaCATGCTGCGGAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5RCV3	Nibrin OS=Pongo abelii OX=9601 GN=NBN PE=2 SV=2
Q6XV80	Nibrin OS=Xenopus laevis OX=8355 GN=nbn.L PE=1 SV=1
O60934	Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004963 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16508 all species →	NIBRIN_BRCT_II	Second BRCT domain on Nijmegen syndrome breakage protein	Domain	Interproscan
PF00498 all species →	FHA	FHA domain	Family	Interproscan
PF08599 all species →	Nbs1_C	DNA damage repair protein Nbs1	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000253 all species →	Domain	Forkhead-associated (FHA) domain	Interproscan
IPR032429 all species →	Domain	Nibrin, second BRCT domain	Interproscan
IPR036420 all species →	Homologous_superfamily	BRCT domain superfamily	Interproscan
IPR008984 all species →	Homologous_superfamily	SMAD/FHA domain superfamily	Interproscan
IPR043014 all species →	Homologous_superfamily	Nibrin, second BRCT domain superfamily	Interproscan
IPR013908 all species →	Domain	Nibrin, C-terminal	Interproscan
IPR040227 all species →	Family	Nibrin-related	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12162 all species →	NIBRIN-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000724 all species →	Biological Process	double-strand break repair via homologous recombination	Interproscan
GO:0003684 all species →	Molecular Function	damaged DNA binding	Interproscan
GO:0006302 all species →	Biological Process	double-strand break repair	Interproscan
GO:0007095 all species →	Biological Process	mitotic G2 DNA damage checkpoint signaling	Interproscan
GO:0030870 all species →	Cellular Component	Mre11 complex	Interproscan
GO:0032508 all species →	Biological Process	DNA duplex unwinding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10867	NBN, NBS1; nibrin	-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.