Gene detail

Detailed information of ENSQPTP00000063846.1 in Actinia mediterranea

Genomic Location: chr3:11379004...11387919
NR annotation: XP_031565949.1, F-box/LRR-repeat protein 5-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000075065

CagattcaaaatggcggctgtcGTGTATTCAGACGAGGTGGATGTCTTCAAAATACCTCACATTCGCATGAAACAGATAGTCTGCGAAGCCACAGAAAAGATCTCTACAACCAATTTTCAAGACAACAGTTCATTGTATGGTCTTTTATCACGGTTTAATAACATCTTCCAAGAACTCAAGCATCATGAAGAAGTAGAAAACAAATGCATTATGGGAAAGCTCCAGCTGCGGCTCACGAATGATCAAATCGCAGCCATAGTCAAAGACATTCATAAACACAGTCATGTGCGGGAGATTTTGTTCCTGATCAAAAGAGGATTTAAAACTGCTaaacgaaaaaagacattgttAAACGTACTCAACTATGAAAGCAAGCTCCGAAGAGCTGTGAATGAGTTTGAGAAAGATTTCTTTCCACACATGAGGCATGAGGAGGAGGTGTTCCAGCCATTGTTAATGGAACACTTCTCTTATGAGGAGCTCAAAATTATCAAAGAAAAAGTGGTCAACTTGCATGTTGCTTTTTCTGAGAGCCATTCTTCAGCTCTTTCCCATGAAACAGATAACAACAATTTTTGTTCTGAGTATGAGTGGAGTTCTTCGGACAGTGAAAGTGGAGATAATGAAACGCTTGTGGATGTCGCACAGACACCTGAAAGACCACTTGCCGTACCATGTTCGTCACAAAAAACTAAAACGCAACTCAAATCCCAACCCATATTATTAAAATTTCCCCCAGAAGTGACATTAAAGATATTCTCGTATCTGAACCCTAAAGACTTGTGCCGTGCTGCCCAGGTCAGTAAAAGCTGGTCAACGTTAGCCAGAGATGGGCAGTTGTGGAAAGAGTTGTATCCTGTCCGGTGGATCTTCCAGAATGATTGGAGATTTGGTGTTGTGAATGAGGAAGACCCTTGTGATTGTAATTGTTCAGGATCATTTGGGACGTTGGaggaagacattgaaagaTTGCTGCAATTAAGAAgTTCATATGCAGATGTAGATGCAGATGTAGATGAATCCTATGACAGTGATGAAGATACAGATGGCACAAGCAGGACACGTACCATGAGATCTCAGTTAGGGAGAATGCTGGACATGGCCAAGAATTTATTTCCATATGTCGGCAAGAATGTCCAAGTATTAAGTCTTGGTTGTTGCCCCTTACTTAGCAATGGGCTGGTGTTCAAGATTTTGTCCCTGTGTCCAAACTTGGAACATCTGAATCTTGCTCAGACGACTGTCACAGACTCTGGAATTAAAGGTTTGTTTCGTAAAGGTGGAGGCTCCAAGCTAAAAGTCCTTGATCTTTCTGGCTGTAAGCTGTTAACAGACAAAACTCTCAACAAACTTTCCTCGTCTCTTGGACAGTACACGTCAAAGACTGACATCGAAGAAGGAGTACATGAGTATACTTTGACATGTGGTTGTATGGCAGATTACTATCCTTCCAACATTTCTAGGTGTTCACTGCAGTTTCTTAGTTTGTCTGGGTGCTATCAAATCACTGATGCTGGCCTAATgtctCTGGCAAGCTTTGGTGGCTTACCAAACCTTCAGTACCTGGACTTATCAGGCTGCCTCAACGTGACGGCTGAAGGTCTGCTACATCTAGTGTCCGTGTGTCCCTCATTAGACCATGCCCAGTTCTTTTACTGTGACAATATTTATGAGGGACCATATCCAGACACAGCCAGTGGGTGCCAAAACCTGGAGTGTACAAACAGAGTGTGCTGCCGACTGGCAGAATAATTCCAGTGatgtttccatggtaaccacAGTTTAAATGAAATTCTGaataatagtttatttgcgctattacattttttttgttcaaatgTGACCCTATCCCTTATTAAACTAAGCAATGCTCCAGTTtcaagttctctgttgctcagccTTAGCCTTggttttgtgcagaatattcatttgttccagtgaaggtccgtggaatttcataGAGTTTGTATTGTTCAAGTTGTGTATTCTTTACattactgttggtatttgtgaatatttagacactaaTTCGAGGCTAATCCTGAGTACATGAGTCTAATCAaagaacacagcggtaatgtGGAAATCCAATAAGGtctattgccctatttcactatgacatcacatgaaaacaaacttttgttttaattaatttaatgaATCATGGTCGAGGGGAATGaaacaagaacaacaacaacccaAAGAAAACTGAGTGACTGAGATGAATAATATTGTAAATTTGATACAGAGCAGGCACAAATGTTGTATTAATTGGTACTTATTATCCAGCTATACTCGGTAGATTAGAGTAGAAATATTGCAGTAGAAAGCCTGCAGTGAGTACATGTACCCTGTATTTATAAGCTGACTACTTTATTTagtacagtaaaaaaaaactattaaaatcaacaaaaaataaaattaaaattaaatccGTTCTGTAAAAAACGGTGGATGACATTAAATGTCTGATAAGATTTACAGTATTCATTAAATCTTTCGGTCAGTATATCATTTcatgttttgttttcaatttgaaGATGATTAAGAGAGGCAAGGTCATCCACTTGACTGTTACAACCTCAACGTTTTTATTCTGAAGTAACATCCACTGTTTCGTACCAGAGAGTAAAGAAAGCTGCAACAATTGCATTTAGGCCGGATTTAGGCATTACATCTTCAATTGgttttatttcacggatatatgacgtactttttttttaccaaagaGTTTTCACTAATATTATATAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5XGI3	F-box/LRR-repeat protein 5 OS=Xenopus tropicalis OX=8364 GN=fbxl5 PE=2 SV=1
Q8C2S5	F-box/LRR-repeat protein 5 OS=Mus musculus OX=10090 GN=Fbxl5 PE=2 SV=2
Q6INS1	F-box/LRR-repeat protein 5 OS=Xenopus laevis OX=8355 GN=fbxl5 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006072 (this species only) · gene tree & orthology
Ubiquitin family	E3\|E3 adaptor Cullin RING\|F-box · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13516 all species →	LRR_6	Leucine Rich repeat	Repeat	Interproscan
PF12937 all species →	F-box-like	F-box-like	Domain	Interproscan
PF01814 all species →	Hemerythrin	Hemerythrin HHE cation binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001810 all species →	Domain	F-box domain	Interproscan
IPR001611 all species →	Repeat	Leucine-rich repeat	Interproscan
IPR032675 all species →	Homologous_superfamily	Leucine-rich repeat domain superfamily	Interproscan
IPR045808 all species →	Domain	FBXL5-like, hemerythrin-like domain	Interproscan
IPR012312 all species →	Domain	Hemerythrin-like	Interproscan
IPR036047 all species →	Homologous_superfamily	F-box-like domain superfamily	Interproscan
IPR006553 all species →	Repeat	Leucine-rich repeat, cysteine-containing subtype	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13318 all species →	UNCHARACTERIZED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0006879 all species →	Biological Process	intracellular iron ion homeostasis	Interproscan
GO:0019005 all species →	Cellular Component	SCF ubiquitin ligase complex	Interproscan
GO:0031146 all species →	Biological Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Interproscan
GO:0055072 all species →	Biological Process	obsolete iron ion homeostasis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10271	FBXL5; F-box and leucine-rich repeat protein 5	-	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →