Gene detail

Detailed information of ENSQPTP00000064356.1 in Actinia mediterranea

Genomic Location: chr3:3684480...3698300
NR annotation: XP_031570548.1, GRAM domain-containing protein 4-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQPTT00000075593

TACAAGACAGTGACTTGTTAGATGAAGCAGAAGTTCACACATCAGAAAAGGCAGATAAAAGCTCGTCTGGCAAAGGAAAAGAAACAGTAAAGCTTTCCGAAGATTCAAATGGCAATTCCCTATCAGAGTCAGAGATGAATTCAGCATCAAACGAAAAAGATTCGATGAGGAAAAAGACTCCTGATCAAAGTGCTCAAGAAGAAAAAGGCTTTCCTAATTCAGAAAGAGAGATCTACGAAATGCAGCTTGTACAACTTCAGGAACAACTTGTTGCTACTATTATATCAGAACAAGAGAAAGATGAACAGCTGATGAAGTACCAACAACTTGACattgaaaagctacaaaagaGCTTGAAAGAGGAGCAAGAAAAGAATGCTGATCTCACAGACAAGCTAAAGATCCTGAAAAACAAGGtccaaaattcaaaattgggAAGAGTAAATGCAAGCAAGTCGGACCCAAGAAAGAAATCTAACCGAAATTCTAAAAATCTTGAAAATGAGTTGAACCAAGATGAAGAATGGACGGACATCAGTTCAGAGAGGAATGCAGAGGATGTTGGCCAAGAAAAATCTGATGACCAAGATGTGCCAAGGTCTGCTAGTGAGAGTAGCTCAAATCCTGAAGTGGAAGAAGAGGATGCATCAAGTGCATTTGAGTTATCACGTTCTAAATCTGTAAAAGATAAGCCAGATGGATTTACCAAACCAACCTCAAGATTTTTTGCTGTAAAGAACTACAAAAACAAGGCAGTTGAAATGATTGTTGAAAGGCTGTGGGATTTTGTTAATGAGGAAACAGAAACAACTGAAGATGATAAAGAAGAAGATGCTCTTTCGGTTAAAAaTTTGAAAGAAAGCATCAACAGATTCTCAAAGGCAATCAAGCCTATCAGCAATTTTATTAAAGGTGTACATAAGCTCATGTCCTGGAACAATTTTGCATCTACCTGTCTGGCATTTATAGTTTACATGTATGCAGCATTTTTTGGCTACCTGTTTTCTCTCGTTCTTCTGATAGCTATTTGGAAACTTTTCATGAATTACCTCTCAGCCAGaGGAATAGCTGCTCAGATTGGACtagaagcaaaagaaaaaaaagaggagacAAATGATGACAAAAGTTTGTCAGACAAGTTTCAACTTGTTTTGGAGGTCGCGAAGAAAGTTCAGaacaCGTTAGGAAAGATAGCCGATTCCcttgaaaaaatagataaTCTATTACTGTGGCAACACCCAGCAACCAACACGCTCTTTTTTAACATCTGCTTGTTGTTTATTGCGTCACTCTGGCTGAGCGGACCAACTATGTTCATGTTCATGGCTCTTGGATTTGGAATAAAAATTTTCATCTTAGGACCATTGTATGATAAGTTCCCCAAGgtTAAAAAGCGTTACGATACTCTTGCTCGTGTTTGGAGTGAACTCCCAAGTGATGCTGACTTAGTGACACGGGAAGTAAATACCGCTGATCAGAACACCACAGACGCGTCTGGCTCGAATGGTGTGGATCATAATGCTTCAGGACGATCTTCACAGAGCTGGATTAATTTCTGTGAGAAAATGAAGATTCCTTCATCAGAAAATCCGCTCCCATCCTGGGAACAAGGTCACCGCTGCACATTGATAAACAAAGACCATCCGCTGACCAACATGAAACATGGCAGGCTCTACTTAACACAGAATCTTTTGTGCTTTGAGAGAAACAAGTCCTCTAAAAacatcgtaataaaactggaAAACATCTTAAGAGCTTCCAAGTGCAAACCAATCAATATGATACCAGGCACTGGAATGGCAATCGAAATTGAAGTCAAAGGATCGAATAAGCCGTACATTTTTGCAGCGTTACTTGGGCGAGACGACGTTTTTGAAAGTTTAATGCTGACTGGCAAAGCAGCAAGCTATCGATGGGCATGTTAGAGGTAGATTAGATACATGGTCTGGAAATGTTTTCGCGGAAGCCGCAAAACGAATAAAATATAGCGCGGGATCAGGGAATTTAGAAAGAAATCTTACGTGATACGGAATAATAGCATCAGCCGTGAATCGGGAATTCCCAACTTCAATGTTCGGGAAGTGGGATTTTGCTTTCTGAGTTTCGggaaaaacatgaaaacattaataaataaaataaaaattcaaacgCCTTTGAATAAGTTGAATGTGGATTGCAAAATGTCGCGCGACGAGGCATTTAGCAAAAAAATAGCCCTTAATCGATATCCGGACCCTAAAAATGGTAACAAGTATCAATATATCATTGCGTGACTTTCGTGACCACTAAATCACGTAACTCTAGTCTAAGTCACGTCTCTAGTCTAGTTTGTTTAGGTTTGTAATCAGgcaaattattttatataatgaaaccttaaataaaaattaccTTCGTATTTTCATACTAGCTCATTATGTGTGAATTGCCTTAAAATGAGATCACGCATTCATTGTCACTCAGTTCAATACTCGGGATGTACGATTAAGATCCATTTTCTCCAGTACTATCGtgatatttggtaccattttcTCCAGTACTACCgggatatttggtaccattttcTCCAGTACTACCgggatatttggtaccattttaTCC

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A2RV80	GRAM domain-containing protein 4 OS=Xenopus laevis OX=8355 GN=gramd4 PE=2 SV=1
Q8CB44	GRAM domain-containing protein 4 OS=Mus musculus OX=10090 GN=Gramd4 PE=1 SV=1
Q6IC98	GRAM domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GRAMD4 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002207 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06398 all species →	Pex24p	Integral peroxisomal membrane peroxin	Family	Interproscan
PF02893 all species →	GRAM	GRAM domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037847 all species →	Family	GRAM domain-containing protein 4	Interproscan
IPR010482 all species →	Domain	Peroxin domain	Interproscan
IPR004182 all species →	Domain	GRAM domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR37402 all species →	GRAM DOMAIN-CONTAINING PROTEIN 4	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006915 all species →	Biological Process	apoptotic process	Interproscan
GO:0034164 all species →	Biological Process	negative regulation of toll-like receptor 9 signaling pathway	Interproscan
GO:0043280 all species →	Biological Process	obsolete positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K23554	GRAMD4; GRAM domain-containing protein 4	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →