Detailed information of ENSQPTP00000066654.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031573677.1, E3 ubiquitin-protein ligase HUWE1-like isoform X1 [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

 Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q7Z6Z7E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3
Q7TMY8E3 ubiquitin-protein ligase HUWE1 OS=Mus musculus OX=10090 GN=Huwe1 PE=1 SV=5
P51593E3 ubiquitin-protein ligase HUWE1 OS=Rattus norvegicus OX=10116 GN=Huwe1 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002420 (this species only)
Ubiquitin familyE3|E3 activity|HECT · all ubiquitin genes in this species
Ubiquitin familyUBD|Alpha-Helix|UBA · all ubiquitin genes in this species
Ubiquitin familyUBD|Alpha-Helix|UBM · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00627
all species →		UBAUBA/TS-N domainDomainInterproscan
PF14377
all species →		UBMUbiquitin binding regionMotifInterproscan
PF06025
all species →		DUF913Domain of Unknown Function (DUF913)FamilyInterproscan
PF02825
all species →		WWEWWE domainFamilyInterproscan
PF06012
all species →		DUF908Domain of Unknown Function (DUF908)FamilyInterproscan
PF00632
all species →		HECTHECT-domain (ubiquitin-transferase)DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR015940
all species →		DomainUbiquitin-associated domainInterproscan
IPR000569
all species →		DomainHECT domainInterproscan
IPR016024
all species →		Homologous_superfamilyArmadillo-type foldInterproscan
IPR035983
all species →		Homologous_superfamilyHECT, E3 ligase catalytic domainInterproscan
IPR025527
all species →		Conserved_siteHUWE1/REV1, ubiquitin-binding motifInterproscan
IPR004170
all species →		DomainWWE domainInterproscan
IPR009060
all species →		Homologous_superfamilyUBA-like superfamilyInterproscan
IPR050409
all species →		FamilyE3 ubiquitin-protein ligaseInterproscan
IPR010314
all species →		DomainE3 ubiquitin ligase, domain of unknown function DUF913Interproscan
IPR037197
all species →		Homologous_superfamilyWWE domain superfamilyInterproscan
IPR010309
all species →		DomainE3 ubiquitin ligase, domain of unknown function DUF908Interproscan
IPR018123
all species →		DomainWWE domain, subgroupInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11254
all species →		HECT DOMAIN UBIQUITIN-PROTEIN LIGASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004842
all species →		Molecular Functionubiquitin-protein transferase activityInterproscan
GO:0005515
all species →		Molecular Functionprotein bindingInterproscan
GO:0000209
all species →		Biological Processprotein polyubiquitinationInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0016567
all species →		Biological Processprotein ubiquitinationInterproscan
GO:0061630
all species →		Molecular Functionubiquitin protein ligase activityInterproscan
GO:0008270
all species →		Molecular Functionzinc ion bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10592HUWE1, MULE, ARF-BP1, TOM1; E3 ubiquitin-protein ligase HUWE1EC:2.3.2.26
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.
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