Genomic Location: chr4:1366844...1386402
NR annotation: XP_031566509.1, histone-lysine N-methyltransferase 2A-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
| CDS |
| ENSQPTT00000079244 |
| Transcript |
| ENSQPTT00000079244 |
| Protein |
| ENSQPTP00000067532.1 |
| UniProt accession | Description |
|---|---|
| O08550 | Histone-lysine N-methyltransferase 2B OS=Mus musculus OX=10090 GN=Kmt2b PE=1 SV=3 |
| Q9UMN6 | Histone-lysine N-methyltransferase 2B OS=Homo sapiens OX=9606 GN=KMT2B PE=1 SV=1 |
| Q03164 | Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004393 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|PHD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13771 all species → | zf-HC5HC2H | PHD-like zinc-binding domain | Domain | Interproscan |
| PF05965 all species → | FYRC | F/Y rich C-terminus | Family | Interproscan |
| PF02008 all species → | zf-CXXC | CXXC zinc finger domain | Domain | Interproscan |
| PF00628 all species → | PHD | PHD-finger | Domain | Interproscan |
| PF05964 all species → | FYRN | F/Y-rich N-terminus | Family | Interproscan |
| PF00856 all species → | SET | SET domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036427 all species → | Homologous_superfamily | Bromodomain-like superfamily | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR003889 all species → | Conserved_site | FY-rich, C-terminal | Interproscan |
| IPR002857 all species → | Domain | Zinc finger, CXXC-type | Interproscan |
| IPR001214 all species → | Domain | SET domain | Interproscan |
| IPR003616 all species → | Domain | Post-SET domain | Interproscan |
| IPR019787 all species → | Domain | Zinc finger, PHD-finger | Interproscan |
| IPR003888 all species → | Conserved_site | FY-rich, N-terminal | Interproscan |
| IPR034732 all species → | Domain | Extended PHD (ePHD) domain | Interproscan |
| IPR046341 all species → | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR001965 all species → | Domain | Zinc finger, PHD-type | Interproscan |
| IPR002219 all species → | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR047219 all species → | Domain | Histone-lysine N-methyltransferase 2A/2B, SET domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45838 all species → | HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0035097 all species → | Cellular Component | histone methyltransferase complex | Interproscan |
| GO:0042800 all species → | Molecular Function | histone H3K4 methyltransferase activity | Interproscan |
| GO:0045893 all species → | Biological Process | positive regulation of DNA-templated transcription | Interproscan |
| GO:0051568 all species → | Biological Process | obsolete histone H3-K4 methylation | Interproscan |
ENSQPTP00000067532.1.Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |