Gene detail

Detailed information of ENSQPTP00000069821.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031551093.1, focal adhesion kinase 1-like isoform X2 [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

No sequence record for ENSQPTP00000069821.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q00944	Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2
Q91738	Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2
P34152	Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003329 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21477 all species →	FERM_C_FAK1	FAK1/PYK2, FERM domain C-lobe	Domain	Interproscan
PF00373 all species →	FERM_M	FERM central domain	Domain	Interproscan
PF03623 all species →	Focal_AT	Focal adhesion targeting region	Domain	Interproscan
PF18038 all species →	FERM_N_2	FERM N-terminal domain	Domain	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR041784 all species →	Domain	FAK1/PYK2, FERM domain C-lobe	Interproscan
IPR049385 all species →	Domain	FAK1-like, FERM domain C-lobe	Interproscan
IPR000299 all species →	Domain	FERM domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR035963 all species →	Homologous_superfamily	FERM superfamily, second domain	Interproscan
IPR019748 all species →	Domain	FERM central domain	Interproscan
IPR005189 all species →	Domain	Focal adhesion kinase, targeting (FAT) domain	Interproscan
IPR036137 all species →	Homologous_superfamily	Focal adhesion kinase, targeting (FAT) domain superfamily	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR019749 all species →	Domain	Band 4.1 domain	Interproscan
IPR014352 all species →	Homologous_superfamily	FERM/acyl-CoA-binding protein superfamily	Interproscan
IPR020635 all species →	Domain	Tyrosine-protein kinase, catalytic domain	Interproscan
IPR041390 all species →	Domain	Focal adhesion kinase, N-terminal	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46221 all species →	FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan
GO:0005925 all species →	Cellular Component	focal adhesion	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0007172 all species →	Biological Process	signal complex assembly	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05725	PTK2, FAK; focal adhesion kinase 1	EC:2.7.10.2	Protein phosphatases and associated proteins	ko01009	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.