Gene detail

Detailed information of ENSQPTP00000070035.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031564459.1, apoptosis-inducing factor 1, mitochondrial-like [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

No sequence record for ENSQPTP00000070035.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O95831	Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1
Q9JM53	Apoptosis-inducing factor 1, mitochondrial OS=Rattus norvegicus OX=10116 GN=Aifm1 PE=1 SV=1
Q9Z0X1	Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005307 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07992 all species →	Pyr_redox_2	Pyridine nucleotide-disulphide oxidoreductase	Domain	Interproscan
PF14721 all species →	AIF_C	Apoptosis-inducing factor, mitochondrion-associated, C-term	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023753 all species →	Domain	FAD/NAD(P)-binding domain	Interproscan
IPR036188 all species →	Homologous_superfamily	FAD/NAD(P)-binding domain superfamily	Interproscan
IPR029324 all species →	Domain	Mitochondrial apoptosis-inducing factor, C-terminal domain	Interproscan
IPR016156 all species →	Homologous_superfamily	FAD/NAD-linked reductase, dimerisation domain superfamily	Interproscan
IPR050446 all species →	Family	FAD-dependent Oxidoreductases and Apoptosis Regulators	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43557 all species →	APOPTOSIS-INDUCING FACTOR 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0046983 all species →	Molecular Function	protein dimerization activity	Interproscan
GO:0050660 all species →	Molecular Function	flavin adenine dinucleotide binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0006915 all species →	Biological Process	apoptotic process	Interproscan
GO:0012501 all species →	Biological Process	programmed cell death	Interproscan
GO:0016174 all species →	Molecular Function	NAD(P)H oxidase H2O2-forming activity	Interproscan
GO:0016651 all species →	Molecular Function	oxidoreductase activity, acting on NAD(P)H	Interproscan
GO:0033108 all species →	Biological Process	mitochondrial respiratory chain complex assembly	Interproscan
GO:0071949 all species →	Molecular Function	FAD binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04727	AIFM1, PDCD8; apoptosis-inducing factor 1	EC:1.-.-.-	Necroptosis	ko04217	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.