Gene detail

Detailed information of ENSQPTP00000074263.1 in Actinia mediterranea

Genomic Location: not available for this species
NR annotation: XP_031574558.1, thioredoxin reductase 2, mitochondrial-like isoform X2 [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families

Sequence

No sequence record for ENSQPTP00000074263.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9NNW7	Thioredoxin reductase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TXNRD2 PE=1 SV=3
Q9JLT4	Thioredoxin reductase 2, mitochondrial OS=Mus musculus OX=10090 GN=Txnrd2 PE=1 SV=4
Q9Z0J5	Thioredoxin reductase 2, mitochondrial OS=Rattus norvegicus OX=10116 GN=Txnrd2 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001656 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02852 all species →	Pyr_redox_dim	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	Domain	Interproscan
PF07992 all species →	Pyr_redox_2	Pyridine nucleotide-disulphide oxidoreductase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR012999 all species →	Active_site	Pyridine nucleotide-disulphide oxidoreductase, class I, active site	Interproscan
IPR016156 all species →	Homologous_superfamily	FAD/NAD-linked reductase, dimerisation domain superfamily	Interproscan
IPR004099 all species →	Domain	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	Interproscan
IPR036188 all species →	Homologous_superfamily	FAD/NAD(P)-binding domain superfamily	Interproscan
IPR046952 all species →	Family	Glutathione reductase/thioredoxin reductase-like	Interproscan
IPR023753 all species →	Domain	FAD/NAD(P)-binding domain	Interproscan
IPR006338 all species →	Family	Thioredoxin/glutathione reductase selenoprotein	Interproscan
IPR001100 all species →	Family	Pyridine nucleotide-disulphide oxidoreductase, class I	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42737 all species →	GLUTATHIONE REDUCTASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016668 all species →	Molecular Function	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0050660 all species →	Molecular Function	flavin adenine dinucleotide binding	Interproscan
GO:0004362 all species →	Molecular Function	glutathione-disulfide reductase (NADPH) activity	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006749 all species →	Biological Process	glutathione metabolic process	Interproscan
GO:0034599 all species →	Biological Process	cellular response to oxidative stress	Interproscan
GO:0045454 all species →	Biological Process	cell redox homeostasis	Interproscan
GO:0004791 all species →	Molecular Function	thioredoxin-disulfide reductase (NADPH) activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K22182	TXNRD; thioredoxin reductase (NADPH)	EC:1.8.1.9	Hepatocellular carcinoma	ko05225	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.