Genomic Location: chr7:8870345...8892188
NR annotation: XP_031575330.1, fermitin family homolog 2-like [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
ENSQPTP00000075429.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q96AC1 | Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1 |
| Q8CIB5 | Fermitin family homolog 2 OS=Mus musculus OX=10090 GN=Fermt2 PE=1 SV=1 |
| F1Q8X5 | Fermitin family homolog 2 OS=Danio rerio OX=7955 GN=fermt2 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006404 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF18124 all species → | Kindlin_2_N | Kindlin-2 N-terminal domain | Domain | Interproscan |
| PF00169 all species → | PH | PH domain | Domain | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR040790 all species → | Domain | Kindlin-2, N-terminal | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR037843 all species → | Family | Kindlin/fermitin | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR16160 all species → | FERMITIN 2-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005178 all species → | Molecular Function | integrin binding | Interproscan |
| GO:0007160 all species → | Biological Process | cell-matrix adhesion | Interproscan |
| GO:0007229 all species → | Biological Process | integrin-mediated signaling pathway | Interproscan |
| GO:0030055 all species → | Cellular Component | cell-substrate junction | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K17083 | FERMT2, KIND2; kindlin 2 | - | Domain-containing proteins not elsewhere classified | ko04990 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
