Genomic Location: not available for this species
NR annotation: XP_031553306.1, smoothened homolog [Actinia tenebrosa]
Species abbreviation AMEDI · all data for this species · gene families
ENSQPTP00000075682.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q5RH73 | Protein smoothened OS=Danio rerio OX=7955 GN=smo PE=1 SV=1 |
| O42224 | Protein smoothened (Fragment) OS=Gallus gallus OX=9031 GN=SMO PE=2 SV=1 |
| Q99835 | Protein smoothened OS=Homo sapiens OX=9606 GN=SMO PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007864 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01392 all species → | Fz | Fz domain | Domain | Interproscan |
| PF01534 all species → | Frizzled | Frizzled/Smoothened family membrane region | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015526 all species → | Family | Frizzled/secreted frizzled-related protein | Interproscan |
| IPR020067 all species → | Domain | Frizzled domain | Interproscan |
| IPR036790 all species → | Homologous_superfamily | Frizzled cysteine-rich domain superfamily | Interproscan |
| IPR000539 all species → | Domain | Frizzled/Smoothened, 7TM | Interproscan |
| IPR017981 all species → | Domain | GPCR, family 2-like, 7TM | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11309 all species → | FRIZZLED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005113 all species → | Molecular Function | patched binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0005929 all species → | Cellular Component | cilium | Interproscan |
| GO:0007224 all species → | Biological Process | smoothened signaling pathway | Interproscan |
| GO:0007389 all species → | Biological Process | pattern specification process | Interproscan |
| GO:0007417 all species → | Biological Process | central nervous system development | Interproscan |
| GO:0016021 all species → | Cellular Component | membrane | Interproscan |
| GO:0030425 all species → | Cellular Component | dendrite | Interproscan |
| GO:0071679 all species → | Biological Process | commissural neuron axon guidance | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0007166 all species → | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0004888 all species → | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06226 | SMO; smoothened | - | G protein-coupled receptors | ko04030 | deepkoala |