Gene detail

Detailed information of ENSQPTP00000078010.1 in Actinia mediterranea

Genomic Location: :...
NR annotation: XP_031557238.1, ras-specific guanine nucleotide-releasing factor 1-like [Actinia tenebrosa]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q13972	Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens OX=9606 GN=RASGRF1 PE=1 SV=2
P28818	Ras-specific guanine nucleotide-releasing factor 1 OS=Rattus norvegicus OX=10116 GN=Rasgrf1 PE=1 SV=1
P27671	Ras-specific guanine nucleotide-releasing factor 1 OS=Mus musculus OX=10090 GN=Rasgrf1 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00621	RhoGEF	RhoGEF domain	Domain	Interproscan
PF00617	RasGEF	RasGEF domain	Family	Interproscan
PF00169	PH	PH domain	Domain	Interproscan
PF00618	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000048	Binding_site	IQ motif, EF-hand binding site	Interproscan
IPR000219	Domain	Dbl homology (DH) domain	Interproscan
IPR001895	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR001849	Domain	Pleckstrin homology domain	Interproscan
IPR035899	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR019804	Conserved_site	Ras guanine-nucleotide exchange factor, conserved site	Interproscan
IPR008937	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR011993	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR000651	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR023578	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan
IPR036964	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0005085	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0007265	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547	Biological Process	positive regulation of GTPase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K04349	RASGRF1; Ras-specific guanine nucleotide-releasing factor 1	-	Focal adhesion	ko04510	deepkoala