Genomic Location: chr8:8903878...8922888
NR annotation: XP_031558664.1, probable E3 ubiquitin-protein ligase HERC4 isoform X1 [Actinia tenebrosa]
Species Actinia mediterranea · all data for this species · gene families
ENSQPTP00000079247.1 in AMEDI (the gene ID may belong to a different isoform naming scheme). Try the gene search.| UniProt accession | Description |
|---|---|
| Q5GLZ8 | Probable E3 ubiquitin-protein ligase HERC4 OS=Homo sapiens OX=9606 GN=HERC4 PE=1 SV=1 |
| Q5PQN1 | Probable E3 ubiquitin-protein ligase HERC4 OS=Rattus norvegicus OX=10116 GN=Herc4 PE=2 SV=1 |
| Q6PAV2 | Probable E3 ubiquitin-protein ligase HERC4 OS=Mus musculus OX=10090 GN=Herc4 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002924 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity|HECT · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 all species → | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00415 all species → | RCC1 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000408 all species → | Repeat | Regulator of chromosome condensation, RCC1 | Interproscan |
| IPR000569 all species → | Domain | HECT domain | Interproscan |
| IPR051210 all species → | Family | Ubiquitin ligases and GEF domain-containing protein | Interproscan |
| IPR035983 all species → | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR009091 all species → | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22870 all species → | REGULATOR OF CHROMOSOME CONDENSATION | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10615 | HERC4; E3 ubiquitin-protein ligase HERC4 | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Actinia mediterranea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Actinia mediterranea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | not in the sequence table | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | not in the sequence table | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
