Gene detail

Detailed information of ENSSJYP00000005978.1 in Catostylus mosaicus

Genomic Location: chr9:1031934...1043139
NR annotation: XP_052089412.1, dihydropyrimidine dehydrogenase [NADP(+)]-like isoform X1 [Mytilus californianus]
Species Catostylus mosaicus · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSSJYT00000006216

ATGCTGCTGTCAAAACATAATAAAGATATAGAGagcattttggcTCTGAACCCAAAGGTTCATGAAAAGGCCAGTCTTGTTCCAACTGCTAAGACACAAAGTAACAAGAAACATTGGAAAAGAAATGCTGATAAACAATGTTCCtCATGCCATGATctgacaaaaaattttgatgatgtgaAGCACACTACACTTAGTGAAAGAGCAGCATTGAAAGAGGCTGCCAGATGCCTGAAATGTGCTGATGCACCATGCCAGAAGAGCTGCCCAACTCAGCTTGACATCAAAGCTTTCATTTCCAGCATAAGCACAAAGAACTACTATGGTGCTGCCAAAGCTATTTTCAGTGACAATCCACTTGGCTTGACATGTGGGATGGTTTGTCCAACAAGTGACCTCTGCGTTGGAGGATGCAATCTTTATGCTGCTGAAGAAGGACCAATCAATATTGGTGGTTTACAGCAATTTGCAACAGAGGTGTTCAAGAACATGCGACTTCCGCAAATCAGAGATCCAAGTCTTCCGAAACATGAAGATTTACCTGAAAGCTACCGTGCCAAGATTGCTTTGATTGGTTGCGGTCCAGCTTCAATCAGTTGTGCAACATTCCTTGCAAGGCTTGGCTATAGTAACATCACCATCTTTGAGAAGGAGGAATATAATGGTGGGCTTAGCTCTTCTGAGATTCCTCAATATCGCCTTCCTTTCGATGTGGTCAAGTTTGAAGTTGAATTGATGAAGGATTTGTCTGTAaagGTTGAGCAAGGAAAACCATTGTCAGTGAATGGTGGTGTAACTATTTCCTCCTTAAAAGAAAGCGGCTACGAAGGAATCTTCCTAGGAATAGGTTTACCACAGCCCAAATTAATCCCCCAATTTGAAGGGTTAACAAAATCTCACGGATTTTGGACCTCAAAAGATTTTCTACCAGTCGTTTCCAAGGGAAGCAAACCAGGATTGTCATGCTGTGACACATCTCTTCCTGATATGAAAGGCAAAGTCATCGTTCTTGGTGCTGGTGACACAGCTTTTGATTGTTGCACTTCTGCGTTGAGATGCGGCGCCAAGCGAGTGTTTGTTGTGTTCAGGAAAGGCTTCACGAACATCCGAGCTGTGCCAGAAGAGATGGAACTTGCAAGAGAGGAAAAATGCGAATTCCTGCCATTTATGTCACCAAAGAAAGTTATTATGAAAGGAGATAGGATAACTGCCATGGAATTTTATAGAACAGAGCAGCTTGATGATGGCACATGGATTGAAGATGAGGAACAAGTGGTCAGAATCAAAAGTGATTATATCATCTCAGCATTTGGATCAACATTGCAAGATGATCAAGTTGTGAAAGCACTTGACCCAGTTAAGTTGTCCAAATGGGGAACGGCAGACATTAACAATGACACAATGGAGACGAATGTACCAGGAATCTTCTGTGGAGGAGATTTTGCTGGAGTGGCACAAACAACAGTTGAATCAGTTAATGATGGTAAAACTGCTGCTTGGTACATGCATGTTTACTTGCAAgGCCTGCACGGTATCCCTGTTATGAGTGAGCAGCCACAACTTCCTTTGTTTTACACGCCTGTTGACTTGGTTGACTTAAGTCTTGATGTTTGCGGCCTAAAATTCCCGAATCCGTTTGGATTAGCCAGTGCTCCGCCAACGACAACATCTGCAATGATGCGAAGGGCATATGAAACTGGTTGGGGCTTTGCATTGACCAAAACATTCTCTCTGGACAAGGACATTGTCACAAACGTGAGCCCAAGGATTGTCCGTGGTAGTACATCTGGTGAGGTATTTGGCCCAGGTCAAGGTTCATTCTTGAACATAGAATTGATCAGTGAGAAATCAGCCGCTTATTGGTGCAAATCAATCACTGAACTTGTCAATGACTTCCCTGATAAAGTATTAATTGCAAGTATAATGTGCGGATATTCCAAAGAGGATTGGACCGAGCTTGCTAAAATGGCCGAGGATGCTGGTGCTCATGCTCTGGAGCTGAATCTATCTTGTCCTCACGGAATGGGAGAAAGAGGAATGGGCCTTGCTTGTGGACAGGATCCGGAACTGGTGCGCAATATTTGTAGATGGGTCAGAGCTGCTGTCAAAAttccattttttgccaaactCACACCAAATGTGACAAACATTGTCACGATTGCTGGAGCTGCAAAAGAAGGTGGTGCAGACGGTTGTACTGCAACAAACACTGTATCTGGCCTGATGCATTTAAAAGGCGATGGAACAGCATGGCCTGCTGTGGGCAAAGAGAAGCGAACAACATACGGTGGTGTATCTGGTAATGCCATTAGACCAATTGCCTTACGTGCAGTCTCTGCCGTTGCTAATGCTCTGCCTGGATTTCCAATACTTGCAACTGGTGGCATTGATAGTGCTGCATCGGCATTGCAGTTCCTACATGCTGGTGCAAGTGTTGTCCAGATTTGCAGTGCGATTCAGAATCAAGATTTCACGGTCATTCAGGATTATATCACTGGCCTTAAATGCTTGCTTTATATGGAAGCTTGTGAAGATTTTGCTGCATGGAATGGACAAAGTATGCCAACACCTAAACACCAGACTGGAAAGCCCGTTGTAATTCAGGAAATCATTGGCAAGGGATTGCCAAACTTCGGCCCTTACAAAGCAAGGAGACAAAAAATCATATCTGATTATAAGAAATCGgtgaatattttaaaagatgGTCTTGACAGTGTACCAGCAAGACCAGCAGTAGAGCCGAAGAAAGATGTTCCTAAAGTTCAGgAGGTAATTGGCGTTGCGTTGTCTCGCATTGGTGCATACGGAAGACTGGATAACAGGCAGCAAGCAGTAGCATTGATTGATGAAGAGATGTGCATTAACTGTGGCAAATGTTACATGACATGCAATGATTCTGGTTACCAGGCGATTACATTTCATCCTGAAACTCATTTGCCCCACATCACCGAAGATTGCACTGGTTGCACTTTGTGTGTTAGCGTTTGCCCAATTATTGATTGCATTACAATGGTTGAACGAAAAACCCCGTACATTCCAAACAGAGGTATTCCCTTGCAAGTCAAATGA

Transcript

ENSSJYT00000006216

AGTTGTTATCAAATGGCATCAGCTTAGCCGGCGGTAGCGTGGCACTCAAACGATAACCACAACAAAAGCAACTGTTTACGCTTAATCATGCTGCTGTCAAAACATAATAAAGATATAGAGagcattttggcTCTGAACCCAAAGGTTCATGAAAAGGCCAGTCTTGTTCCAACTGCTAAGACACAAAGTAACAAGAAACATTGGAAAAGAAATGCTGATAAACAATGTTCCtCATGCCATGATctgacaaaaaattttgatgatgtgaAGCACACTACACTTAGTGAAAGAGCAGCATTGAAAGAGGCTGCCAGATGCCTGAAATGTGCTGATGCACCATGCCAGAAGAGCTGCCCAACTCAGCTTGACATCAAAGCTTTCATTTCCAGCATAAGCACAAAGAACTACTATGGTGCTGCCAAAGCTATTTTCAGTGACAATCCACTTGGCTTGACATGTGGGATGGTTTGTCCAACAAGTGACCTCTGCGTTGGAGGATGCAATCTTTATGCTGCTGAAGAAGGACCAATCAATATTGGTGGTTTACAGCAATTTGCAACAGAGGTGTTCAAGAACATGCGACTTCCGCAAATCAGAGATCCAAGTCTTCCGAAACATGAAGATTTACCTGAAAGCTACCGTGCCAAGATTGCTTTGATTGGTTGCGGTCCAGCTTCAATCAGTTGTGCAACATTCCTTGCAAGGCTTGGCTATAGTAACATCACCATCTTTGAGAAGGAGGAATATAATGGTGGGCTTAGCTCTTCTGAGATTCCTCAATATCGCCTTCCTTTCGATGTGGTCAAGTTTGAAGTTGAATTGATGAAGGATTTGTCTGTAaagGTTGAGCAAGGAAAACCATTGTCAGTGAATGGTGGTGTAACTATTTCCTCCTTAAAAGAAAGCGGCTACGAAGGAATCTTCCTAGGAATAGGTTTACCACAGCCCAAATTAATCCCCCAATTTGAAGGGTTAACAAAATCTCACGGATTTTGGACCTCAAAAGATTTTCTACCAGTCGTTTCCAAGGGAAGCAAACCAGGATTGTCATGCTGTGACACATCTCTTCCTGATATGAAAGGCAAAGTCATCGTTCTTGGTGCTGGTGACACAGCTTTTGATTGTTGCACTTCTGCGTTGAGATGCGGCGCCAAGCGAGTGTTTGTTGTGTTCAGGAAAGGCTTCACGAACATCCGAGCTGTGCCAGAAGAGATGGAACTTGCAAGAGAGGAAAAATGCGAATTCCTGCCATTTATGTCACCAAAGAAAGTTATTATGAAAGGAGATAGGATAACTGCCATGGAATTTTATAGAACAGAGCAGCTTGATGATGGCACATGGATTGAAGATGAGGAACAAGTGGTCAGAATCAAAAGTGATTATATCATCTCAGCATTTGGATCAACATTGCAAGATGATCAAGTTGTGAAAGCACTTGACCCAGTTAAGTTGTCCAAATGGGGAACGGCAGACATTAACAATGACACAATGGAGACGAATGTACCAGGAATCTTCTGTGGAGGAGATTTTGCTGGAGTGGCACAAACAACAGTTGAATCAGTTAATGATGGTAAAACTGCTGCTTGGTACATGCATGTTTACTTGCAAgGCCTGCACGGTATCCCTGTTATGAGTGAGCAGCCACAACTTCCTTTGTTTTACACGCCTGTTGACTTGGTTGACTTAAGTCTTGATGTTTGCGGCCTAAAATTCCCGAATCCGTTTGGATTAGCCAGTGCTCCGCCAACGACAACATCTGCAATGATGCGAAGGGCATATGAAACTGGTTGGGGCTTTGCATTGACCAAAACATTCTCTCTGGACAAGGACATTGTCACAAACGTGAGCCCAAGGATTGTCCGTGGTAGTACATCTGGTGAGGTATTTGGCCCAGGTCAAGGTTCATTCTTGAACATAGAATTGATCAGTGAGAAATCAGCCGCTTATTGGTGCAAATCAATCACTGAACTTGTCAATGACTTCCCTGATAAAGTATTAATTGCAAGTATAATGTGCGGATATTCCAAAGAGGATTGGACCGAGCTTGCTAAAATGGCCGAGGATGCTGGTGCTCATGCTCTGGAGCTGAATCTATCTTGTCCTCACGGAATGGGAGAAAGAGGAATGGGCCTTGCTTGTGGACAGGATCCGGAACTGGTGCGCAATATTTGTAGATGGGTCAGAGCTGCTGTCAAAAttccattttttgccaaactCACACCAAATGTGACAAACATTGTCACGATTGCTGGAGCTGCAAAAGAAGGTGGTGCAGACGGTTGTACTGCAACAAACACTGTATCTGGCCTGATGCATTTAAAAGGCGATGGAACAGCATGGCCTGCTGTGGGCAAAGAGAAGCGAACAACATACGGTGGTGTATCTGGTAATGCCATTAGACCAATTGCCTTACGTGCAGTCTCTGCCGTTGCTAATGCTCTGCCTGGATTTCCAATACTTGCAACTGGTGGCATTGATAGTGCTGCATCGGCATTGCAGTTCCTACATGCTGGTGCAAGTGTTGTCCAGATTTGCAGTGCGATTCAGAATCAAGATTTCACGGTCATTCAGGATTATATCACTGGCCTTAAATGCTTGCTTTATATGGAAGCTTGTGAAGATTTTGCTGCATGGAATGGACAAAGTATGCCAACACCTAAACACCAGACTGGAAAGCCCGTTGTAATTCAGGAAATCATTGGCAAGGGATTGCCAAACTTCGGCCCTTACAAAGCAAGGAGACAAAAAATCATATCTGATTATAAGAAATCGgtgaatattttaaaagatgGTCTTGACAGTGTACCAGCAAGACCAGCAGTAGAGCCGAAGAAAGATGTTCCTAAAGTTCAGgAGGTAATTGGCGTTGCGTTGTCTCGCATTGGTGCATACGGAAGACTGGATAACAGGCAGCAAGCAGTAGCATTGATTGATGAAGAGATGTGCATTAACTGTGGCAAATGTTACATGACATGCAATGATTCTGGTTACCAGGCGATTACATTTCATCCTGAAACTCATTTGCCCCACATCACCGAAGATTGCACTGGTTGCACTTTGTGTGTTAGCGTTTGCCCAATTATTGATTGCATTACAATGGTTGAACGAAAAACCCCGTACATTCCAAACAGAGGTATTCCCTTGCAAGTCAAATGAACATTAAATCTTGTTTGAACTTGTGACTGtgcaatctttttatttcttagtGTTTTTGGGATTGTTGTCATGTCAAATTCATATATTGCCTGAATCAAGTATTAGTTCTTATATTCATGTcgattttatatatttttagtattttatccatttttgGGGAAGGGGCTAACTTCGGGCTGGGGATCACCAATTTGCCATTCTTCACCTTCATCAGTTTAGAAATACGTTAAAATCTGAAGTAAACATtcctttcattgtttttatttaccaTTTAATATCGAAAGCAATTGGGCGTACTTGTACGTGAAAATGACGAAAATGACAATTGCACTGGGAGGTGATGATGCTTGGTGAGCCTCACTGCCCCTTTTTACTCCCGTATTTTTGCCTTTGTAAGGTAAATAGAATTCATAAAACAATGCTCATATTTCAAGCTCATTAACAAATTCTAAACATTATTGAACTATACAACTTAAGATTTTCGATTGATTATATCAGGTTTGAGGACGTGCCTTTTAGAAATGTGTAATGATTTCCATTAAgtattttgtgcttttttctacATTGTGTCTTCGTTTTTAGTGGCGGCGGGGAATCGGTAAGGCGCAGGTCTTTTAATTTCGTAACTAACCCAGTCTAATAATCATCCTTTCCGTATTCTCCCTTCCGAAATTAGTAATTACAGGCGACACAGGCCGTAGCGCAACAGGCCAACATCTAATGAATAGCTGCCAGAATCCCAGACTGTGTTAGCAAgtgaaattagaaaagaaataagtaTCATTTAAGTTGCAAAACTGCCAAGGGGTTTGAGGGTGTTGCTTAGGCTTCTACACTAGgcagtttaaaaaaatgattttcaaagagTTATTAAacgaaaaactaggagttatcaatgtttcttcaaaatgaaaatatagatAAGACTT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6NYG8	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Danio rerio OX=7955 GN=dpyd PE=2 SV=1
Q12882	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Homo sapiens OX=9606 GN=DPYD PE=1 SV=2
Q8CHR6	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Mus musculus OX=10090 GN=Dpyd PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003061 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF14691 all species →	Fer4_20	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	Domain	Interproscan
PF07992 all species →	Pyr_redox_2	Pyridine nucleotide-disulphide oxidoreductase	Domain	Interproscan
PF14697 all species →	Fer4_21	4Fe-4S dicluster domain	Domain	Interproscan
PF01180 all species →	DHO_dh	Dihydroorotate dehydrogenase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017896 all species →	Domain	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Interproscan
IPR017900 all species →	Conserved_site	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Interproscan
IPR028261 all species →	Domain	Dihydroprymidine dehydrogenase domain II	Interproscan
IPR023753 all species →	Domain	FAD/NAD(P)-binding domain	Interproscan
IPR005720 all species →	Domain	Dihydroorotate dehydrogenase, catalytic	Interproscan
IPR036188 all species →	Homologous_superfamily	FAD/NAD(P)-binding domain superfamily	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan
IPR001295 all species →	Conserved_site	Dihydroorotate dehydrogenase, conserved site	Interproscan
IPR009051 all species →	Homologous_superfamily	Alpha-helical ferredoxin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43073 all species →	DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0002058 all species →	Molecular Function	uracil binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006210 all species →	Biological Process	thymine catabolic process	Interproscan
GO:0006212 all species →	Biological Process	uracil catabolic process	Interproscan
GO:0017113 all species →	Molecular Function	dihydropyrimidine dehydrogenase (NADP+) activity	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0016627 all species →	Molecular Function	oxidoreductase activity, acting on the CH-CH group of donors	Interproscan
GO:0006207 all species →	Biological Process	'de novo' pyrimidine nucleobase biosynthetic process	Interproscan
GO:0051536 all species →	Molecular Function	iron-sulfur cluster binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00207	DPYD; dihydropyrimidine dehydrogenase (NADP+)	EC:1.3.1.2	Drug metabolism - other enzymes	ko00983	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Catostylus mosaicus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Catostylus mosaicus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →