Gene detail

Detailed information of ENSSJYP00000012185.1 in Catostylus mosaicus

Genomic Location: not available for this species
NR annotation: XP_020615249.1, eIF-2-alpha kinase GCN2-like [Orbicella faveolata]
Species Catostylus mosaicus · all data for this species · gene families

Sequence

CDS

ENSSJYT00000012723

GATGATAGAATGGACCAAAGCAACCAGGAACGTCAAGAGGAGGAACTCCAAGTCTTAGAGGCAATCTACATGAGTGAATTTGTTGACTTGAGAAGTGACCATCcaccaatagtatgcttgaAACTGACGCCTCTTCAGAGTATAATGAGACATGAAGTCCATGCCAAGGTGGATTTGGTCGTGAAATACACAACAAGATACCCAACAGACCCACCAATTCTTCGACTAGAAAATCCAAAAGGTCTTTCCAATGAGCAGgtagcaaaattgaaaaaagatctGGATGATCAAGCAAAAGAATTGACTGGAGagGTAATGGTCTTGCAACTTGCACAGTCTGTTCAGGCTTTCCTGCACAAACACAATGTCccaacattttcttttcacgaacaaatgttaaaaaacatgcaaaaagagaaagaaataaaggaaatgGAAAGAGAGAAGAGACTTGCAAAGGATAAAGCTCAAGCAAAggaatttgatgatgatgtggtaattatttttgtttataatcCTGTATTAAGCGCCTGTGCAAGGGCTGGAATAGATGTGGAGAGTGGGGATGTTGTTACTGTCTGTGAATGGAGTTTTAACAGAAAACGCGACAAGCAAAAGTCATCTTTTTCAATTGGAAGCAGTCTTGATTCTGATAATATTACGAAGCAGGTAGGCCAAATTCACTTTTATTTAATTGTTGTTACCTCTAATAACTGTGTATTTTTCCAGATATTAATGGATAACATTGATGGATATTGTGTATCAGACGATATCGACCCTCCTGGTTTATCATTCGATATCGTACAAGATTACGCAAAGCAACTTGTTAATGTTTTGTATCACCTTCACAATAAATCAGTTGTACACAAAGATTTAAAGgGATTGGTTGTTCTATCAATGCTGCAAGGAAAGATTCCAACAGGTTATCCAGTTGAAATACCAGCAGGCCTACCCGACGATGCGCAAGATTTCCTTTTAAAaTGTCTAAacattgatgaaaaagaaagatggaCTATCTCTCAACTTGTCAAGCATCCATTCCTTATTGCTGCCAacacaacaaaaaacaatatagCTCTTGCTGCGGCGGACAATTCTAACGGACATGATGAAGCGGACAAACAATTAGAAGAGGAAAATTTCCTACGGacattgaatgaattaaacattgcaaataaaacacGACTAATGACAGACTTTGAGATTCTTGATTCCCTTGGTCAAGGAGGTTTTGGAAGTGTTATCAAGGTAAGAAAGAAACTCGATGGTCTTCTTTATGCAATAAAAAGGATAAACTTGGACCCAAAATCTGCCCAgttgaaaaaaagaattattcGAGAAGTGAAGTTGCTGTCACGATTAAATCACGAAAATGTCGTCAGATACTACAGCTCGTGGATAGAAGCCGAAGAATGTACTAATGACGAGACGACATCATCAGAATCTTTAGGAAGGAGTGAGATTCTGCAGCGGAAGAAAACAGGTAACGATAATCAGAAAGCTGAAACTGAAAACACTGAGGACAGTTTATTAAAATACCATGATTTTGATGCACCAAGCATGGCGAGGGGCCGTGAAGGTGATGATTTTTCATGGAGTGACGACAAAGATGATGAAGACTCCAAGGGACAAAGCAGTGACAGTGATTCATCTACAGacgatgaagaagatgaagaagatgaagtagAAGAGTTtaaggtgacaagaaaacaTGGCATGAATTTcTTTCCTCTGAAACGTAGCCTTGATTTGTTCACATTACAGGAAGAATCAGAATGCGAGCTGCCAATGACGTTGGAAACTTCGGAGGAGCCTTCAGTTGAAGGGacaaggtttcaaaaatactTGTACATCCAAATGGAATATTGCGAGAAGAGCACGTTAAGGAATGTTATTGATGAAGGTCTTTACAAAAATCCAAGTCGTATGTGGAGGCTGTTTAGGGAGATTGTCGAAGGGCTTTCGCATGTCCATTCCCAGGGAATTATTCACCGTGATCTTAAACCATTTAACATCTTCATGGATTCACGTGATCAAGTCAAGATTGGCGATTTCGGATTGGCTACATCTCACACGATCAACCAAGTCACCGATCACTCATTGGCTGCTATGAGCATGACGTCAGATGGTAAATTATCTACAGACTCGTCTAACCGTATGACTGGAAAAGTCGGAACGGCTCTGTATGTGGCCCCGGAGATCGATGCCTTTGGACTGAAGGtcaaaatcactgaaaaagtTGATTTATATAGCTTGGGAGTTATTTTCTTCGAGATGTGTTATAAGCCTTTGCCAACTGGTATGGAACGAGTGAAAATACTTGGGCTCTTACGAACTGAAAGGATCGTACTCCCTGTTGATTTTGAAGATAAACCCCGTCCTGTTGAGAAGAAGATTCTTCACTGGCTGCTAAATCACAATTTCGAAGAGCGGCCAACAGCCTCGGAACTTTTAGAAAGCGGCCTTGTGCCTCCCAAGCTCGAGGATCGTCATTTTGACGAATTACTAGCATTAACATTGAAACAACCTAGTTCTACAAGATACAAGCGTTTAACTGCAGCCCTCTTTAACCAGAACACCGACCCAGTAACCGACCAAATCTATGACAAGCATCTAGATAAGAAACAGGAGGGCTTTCTTCTATCAGTGCATGCGCACGAATATGTTGAGCAAGCAATTCGGGGTATTTTTACACGTCATGGTGCTACGCATCTAGACATACCTCTCTTTATGCCAAAATGCCGGTTGTTTGAGCAGCAAGGCTGGATAACGAATGTAATGGACCCGGATGGCATCATTTTGTCGCTGCCCTTTGATTCCAGAGTCAGCCTTGCAAGATATATTTCAAGGAATAACGTCAGAAATATTAAGAGGTATAACATTGGGAATGTTTACAGAGATACAAAAATTAGTCGCACGCACCCgaaagaaattaaagagtGTACTTTCGATATTGTTAGTGATGCAGCGTCGAATTCCTTGGTGCCAGATGCAGAAGTACTTTACGCTGTAGATGAAATTGTCCAACAATTTCCATGTTTACGAAATAGAAACTTTCAAGTTCTCGTCAATCATACAAATTTGCTCAAGGCCATTTTACTGCAAGCAAACATCGATGATGCGCAACTAAACAAAGTCTTTTCGATTCTCCAATCTTCCAAAGATTCGAAAGATTGCGTTCAAAAAGTTAAACAGTATTTAACCGATGAAGGTATACCAGAACACACGGTAACGAAAACTGTTAGTCTTCTCGATTTTGAAGGTCCGATAAAGAAAGCGCGTGAAAGTCTACAAAGTGTTCGAAAATCAAGAGGTATTGTTGGTTCTCTTGCAAAGCAAGCGTTAATCGACCTgacaaacttctgcaaaagtgCTCAAGCATTTGGCCTTGAAATGCCAATAGTAATACAGACATGCCTGGCCTATAACCTCAGTGTATTCTCAGGggttgtttttcaaattgttgcTGAGAACAAACGAAAACGAAAGCTTGGAAGTGTTGACATTTTGGCTGGCGGTGGAAGATATGACAGTTTGCTTGAGAGTTTCAAGATGGCAGGCGAACAGAAAGCGCTTCCGCGTGCTGCTGGAGTCAGTATTGCGTTTGAGAAGATCGTGAATGCAATTCTTAAGGAGATAAGAGATAACGAATACATGCTATCCGATCTAAGCTGCTGCGATGTTCTTGTTGGAGTCATTGGTGAGACAACTCTACCGGAGCAAAGACTTGGAGTGGTTAGAGAATTATGGGCTCACGGTATCAGAGCAATGTTATCATCATACGAAGCACAGCAAGATTGCACTCCTGAATCACTTCAAGATCTCTGCAAAGAGGCTGGCATTAATCATTTCGTTTTGTTGAAATCATCTGAAAACGACTTTGTTCGAGTCGATCTTCCACCAATAGCAATGAGAAACCTATTCGCTCATTTAGATATAGATGCAGATGAAGAAGAGTTTGGAGCAAGCGTTTCAGATATAATCGATAAACagaagttgaagaaaatagCCTTGTACATACATAGAATTTGTTCTACCCTAAGGGAAatcaaaaaggaaagaaatattgtCATGATATATGGGTATAAAGAAGACTTTTATagaatttttgtgtaa

Transcript

ENSSJYT00000012723

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9P2K8	eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3
Q9QZ05	eIF-2-alpha kinase GCN2 OS=Mus musculus OX=10090 GN=Eif2ak4 PE=1 SV=2
D4A7V9	eIF-2-alpha kinase GCN2 OS=Rattus norvegicus OX=10116 GN=Eif2ak4 PE=3 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002825 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13393 all species →	tRNA-synt_His	Histidyl-tRNA synthetase	Domain	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF12745 all species →	HGTP_anticodon2	Anticodon binding domain of tRNAs	Domain	Interproscan
PF05773 all species →	RWD	RWD domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR041715 all species →	Domain	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR050339 all species →	Family	Cell Cycle and Stress Response Kinase	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR045864 all species →	Homologous_superfamily	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	Interproscan
IPR006575 all species →	Domain	RWD domain	Interproscan
IPR016135 all species →	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR024435 all species →	Domain	Histidyl tRNA synthetase-related domain	Interproscan
IPR036621 all species →	Homologous_superfamily	Anticodon-binding domain superfamily	Interproscan
IPR016255 all species →	Family	eIF-2-alpha kinase Gcn2	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11042 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004694 all species →	Molecular Function	eukaryotic translation initiation factor 2alpha kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0010998 all species →	Biological Process	regulation of translational initiation by eIF2 alpha phosphorylation	Interproscan
GO:1990625 all species →	Biological Process	negative regulation of cytoplasmic translational initiation in response to stress	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000077 all species →	Biological Process	DNA damage checkpoint signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K16196	EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4	EC:2.7.11.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.