Genomic Location: not available for this species
NR annotation: XP_032242612.2, DNA topoisomerase 2-alpha isoform X2 [Nematostella vectensis]
Species abbreviation CMOSA · all data for this species · gene families
| CDS |
| ENSSJYT00000013501 |
| Transcript |
| ENSSJYT00000013501 |
| Protein |
| ENSSJYP00000012932.1 |
| UniProt accession | Description |
|---|---|
| O42131 | DNA topoisomerase 2-beta OS=Gallus gallus OX=9031 GN=TOP2B PE=2 SV=1 |
| Q02880 | DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 |
| Q64511 | DNA topoisomerase 2-beta OS=Mus musculus OX=10090 GN=Top2b PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002437 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00521 all species → | DNA_topoisoIV | DNA gyrase/topoisomerase IV, subunit A | Family | Interproscan |
| PF16898 all species → | TOPRIM_C | C-terminal associated domain of TOPRIM | Family | Interproscan |
| PF01751 all species → | Toprim | Toprim domain | Family | Interproscan |
| PF00204 all species → | DNA_gyraseB | DNA gyrase B | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013758 all species → | Homologous_superfamily | DNA topoisomerase, type IIA, domain A, alpha-beta | Interproscan |
| IPR002205 all species → | Domain | DNA topoisomerase, type IIA, domain A | Interproscan |
| IPR006171 all species → | Domain | TOPRIM domain | Interproscan |
| IPR013759 all species → | Homologous_superfamily | DNA topoisomerase, type IIA, subunit B, C-terminal | Interproscan |
| IPR001154 all species → | Family | DNA topoisomerase II, eukaryotic-type | Interproscan |
| IPR034157 all species → | Domain | DNA topoisomerase 2, TOPRIM domain | Interproscan |
| IPR031660 all species → | Domain | C-terminal associated domain of TOPRIM | Interproscan |
| IPR018522 all species → | Conserved_site | DNA topoisomerase, type IIA, conserved site | Interproscan |
| IPR013760 all species → | Homologous_superfamily | DNA topoisomerase, type IIA-like domain superfamily | Interproscan |
| IPR001241 all species → | Family | DNA topoisomerase, type IIA | Interproscan |
| IPR014721 all species → | Homologous_superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Interproscan |
| IPR013506 all species → | Domain | DNA topoisomerase, type IIA, subunit B, domain 2 | Interproscan |
| IPR050634 all species → | Family | DNA Topoisomerase II Enzyme | Interproscan |
| IPR013757 all species → | Homologous_superfamily | DNA topoisomerase, type IIA, alpha-helical domain superfamily | Interproscan |
| IPR020568 all species → | Homologous_superfamily | Ribosomal protein uS5 domain 2-type superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10169 all species → | DNA TOPOISOMERASE/GYRASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0003918 all species → | Molecular Function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0006259 all species → | Biological Process | DNA metabolic process | Interproscan |
| GO:0006265 all species → | Biological Process | DNA topological change | Interproscan |
| GO:0000712 all species → | Biological Process | resolution of meiotic recombination intermediates | Interproscan |
| GO:0000819 all species → | Biological Process | sister chromatid segregation | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03164 | TOP2; DNA topoisomerase II | EC:5.6.2.2 | Chromosome and associated proteins | ko03036 | deepkoala |
