Genomic Location: chr12:2608149...2616612
NR annotation: XP_020627164.1, LETM1 and EF-hand domain-containing protein 1, mitochondrial-like isoform X1 [Orbicella faveolata]
Species Catostylus mosaicus · all data for this species · gene families
| CDS |
| ENSSJYT00000021676 |
| Transcript |
| ENSSJYT00000021676 |
| Protein |
| ENSSJYP00000020761.1 |
| UniProt accession | Description |
|---|---|
| Q5ZK33 | Mitochondrial proton/calcium exchanger protein OS=Gallus gallus OX=9031 GN=LETM1 PE=2 SV=1 |
| Q0VCA3 | Mitochondrial proton/calcium exchanger protein OS=Bos taurus OX=9913 GN=LETM1 PE=2 SV=1 |
| O95202 | Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005018 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13202 all species → | EF-hand_5 | EF hand | Domain | Interproscan |
| PF07766 all species → | LETM1_RBD | LETM1-like, RBD | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002048 all species → | Domain | EF-hand domain | Interproscan |
| IPR033122 all species → | Domain | LETM1-like, ribosome-binding domain | Interproscan |
| IPR018247 all species → | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR044202 all species → | Family | LETM1/MDM38-like | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14009 all species → | LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0043022 all species → | Molecular Function | ribosome binding | Interproscan |
| GO:0005743 all species → | Cellular Component | mitochondrial inner membrane | Interproscan |
| GO:0006875 all species → | Biological Process | obsolete intracellular metal ion homeostasis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K17800 | LETM1, MDM38; LETM1 and EF-hand domain-containing protein 1, mitochondrial | - | Transporters | ko02000 | deepkoala |
Genes whose expression across the transcriptome samples of Catostylus mosaicus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Catostylus mosaicus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |